Primary Site >> Liver Cancer

Gene >> WT1

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Ref: Wilms' tumor 1-KTS isoforms induce p53-independent apoptosis that can be partially rescued by expression of the epidermal growth factor receptor or the insulin receptor.
PMID: 9102224
Ref: Relationship between loss of heterozygosity of tumor suppressor genes and histologic differentiation in hepatocellular carcinoma.
PMID: 9307185
Ref: Characterization of six tumor suppressor genes and microsatellite instability in hepatocellular carcinoma in southern African blacks.
PMID: 11819494
Ref: Distinctive gene expression profiles associated with Hepatitis B virus x protein.
PMID: 11439330
Ref: Loss of heterozygosity of chromosome 8p and 11p in the dysplastic nodule and hepatocellular carcinoma.
PMID: 12653892
Ref: Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms.
PMID: 12807729
Ref: Methylation profiling of twenty four genes and the concordant methylation behaviours of nineteen genes that may contribute to hepatocellular carcinogenesis.
PMID: 14672555
Ref: Desmoplastic nested spindle cell tumor of liver: report of four cases of a proposed new entity.
PMID: 15613851
Ref: Inhibition of Wilms tumor xenograft progression by halofuginone is accompanied by activation of WT-1 gene expression.
PMID: 16148645
Ref: CpG island methylator phenotype association with elevated serum alpha-fetoprotein level in hepatocellular carcinoma.
PMID: 17289889
Ref: Re-expression of tumorigenicity after attenuation of human synaptotagmin 13 in a suppressed microcell hybrid cell line.
PMID: 18202767
Ref: Wilms' tumour 1 gene expression is increased in hepatocellular carcinoma and associated with poor prognosis.
PMID: 18255279
Ref: In vitro generation of cytotoxic and regulatory T cells by fusions of human dendritic cells and hepatocellular carcinoma cells.
PMID: 18793383
Ref: Wilms' tumor 1 gene expression in hepatocellular carcinoma promotes cell dedifferentiation and resistance to chemotherapy.
PMID: 19190340
Ref: [Effect of RNAi silencing of theWT1 gene on the apoptosis of human hepatocellular carcinoma cell hepG2].
PMID: 20619105
Ref: RNAa-mediated overexpression of WT1 induces apoptosis in HepG2 cells.
PMID: 22244202
Ref: Wilms' tumor 1 gene modulates Fas-related death signals and anti-apoptotic functions in hepatocellular carcinoma.
PMID: 23142971
Ref: Nested stromal epithelial tumor of the liver in Beckwith-Wiedemann syndrome.
PMID: 23570373
Ref: WT1-AS promotes cell apoptosis in hepatocellular carcinoma through down-regulating of WT1.
PMID: 26462627
Ref: Facing the enigma of the vascular network in hepatocellular carcinomas in cirrhotic and non-cirrhotic livers.
PMID: 26243063
Ref: Aberrant methylation of tumour suppressor genes WT1, GATA5 and PAX5 in hepatocellular carcinoma.
PMID: 27171388
Ref: Meta-analysis of DNA methylation biomarkers in hepatocellular carcinoma.
PMID: 27835605
Ref: Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde.
PMID: 29285297
Ref: Efficacy of ONC201 in Desmoplastic Small Round Cell Tumor.
PMID: 29626752
Ref: Repression of WT1-Mediated LEF1 Transcription by Mangiferin Governs beta-Catenin-Independent Wnt Signalling Inactivation in Hepatocellular Carcinoma.
PMID: 29953980