Primary Site >> Stomach Cancer

Gene >> WNT5A

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Ref: Molecular cloning and characterization of human WNT5B on chromosome 12p13.3 region.
PMID: 11445850
 Ref: Frequent up-regulation of WNT5A mRNA in primary gastric cancer.
PMID: 11956659
Ref: Expression and regulation of WNT5A and WNT5B in human cancer: up-regulation of WNT5A by TNFalpha in MKN45 cells and up-regulation of WNT5B by beta-estradiol in MCF-7 cells.
PMID: 12165812
 Ref: Comparative genomics on ROR1 and ROR2 orthologs.
PMID: 16211313
Ref: WNT/PCP signaling pathway and human cancer (review).
PMID: 16273260
 Ref: Comparative integromics on FAT1, FAT2, FAT3 and FAT4.
PMID: 16865240
 Ref: Conserved POU-binding site linked to SP1-binding site within FZD5 promoter: Transcriptional mechanisms of FZD5 in undifferentiated human ES cells, fetal liver/spleen, adult colon, pancreatic islet, and diffuse-type gastric cancer.
PMID: 17273778
Ref: Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer.
PMID: 17568183
 Ref: Cross talk between hedgehog and epithelial-mesenchymal transition pathways in gastric pit cells and in diffuse-type gastric cancers.
PMID: 19107131
Ref: Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades.
PMID: 19424602
Ref: Laminin gamma2 mediates Wnt5a-induced invasion of gastric cancer cells.
PMID: 19582886
Ref: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.
PMID: 19860666
 Ref: beta-Catenin-independent noncanonical Wnt pathway might be induced in gastric cancers.
PMID: 20931424
 Ref: An anti-Wnt5a antibody suppresses metastasis of gastric cancer cells in vivo by inhibiting receptor-mediated endocytosis.
PMID: 22101459
Ref: Gastric cancer development after Helicobacter pylori eradication therapy: a new form of gastric neoplasia.
PMID: 22223100
Ref: Mesenchymal stem cells provide an advantageous tumor microenvironment for the restoration of cancer stem cells.
PMID: 22688186
Ref: Methylation of the WNT5A gene is frequently detected in early gastric carcinoma.
PMID: 23178630
 Ref: Epigenetic silencing of WNT5A in Epstein-Barr virus-associated gastric carcinoma.
PMID: 23001722
Ref: SFRP5 inhibits gastric epithelial cell migration induced by macrophage-derived Wnt5a.
PMID: 23054609
Ref: PI3K/Akt-dependent phosphorylation of GSK3beta and activation of RhoA regulate Wnt5a-induced gastric cancer cell migration.
PMID: 23123500
Ref: WNT5A is a key regulator of the epithelial-mesenchymal transition and cancer stem cell properties in human gastric carcinoma cells.
PMID: 23615002
Ref: WNT5A encodes two isoforms with distinct functions in cancers.
PMID: 24260410
 Ref: PATHOME: an algorithm for accurately detecting differentially expressed subpathways.
PMID: 24681952
Ref: IL-1beta mediates MCP-1 induction by Wnt5a in gastric cancer cells.
PMID: 24993819
 Ref: Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively.
PMID: 25622531
Ref: EGF-reduced Wnt5a transcription induces epithelial-mesenchymal transition via Arf6-ERK signaling in gastric cancer cells.
PMID: 25779663
 Ref: HNF4alpha is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer.
PMID: 25410163
Ref: Role for Daple in non-canonical Wnt signaling during gastric cancer invasion and metastasis.
PMID: 26577606
Ref: Wnt5a-Ror2 signaling in mesenchymal stem cells promotes proliferation of gastric cancer cells by activating CXCL16-CXCR6 axis.
PMID: 26708384
Ref: Lifting the Mist on Gastric Stem Cells.
PMID: 26748749
Ref: Distinct miRNA profiles in normal and gastric cancer myofibroblasts and significance in Wnt signaling.
PMID: 26939869
Ref: ROR2 inhibits the proliferation of gastric carcinoma cells via activation of non-canonical Wnt signaling.
PMID: 28101190
 Ref: COL11A1 is overexpressed in gastric cancer tissues and regulates proliferation, migration and invasion of HGC-27 gastric cancer cells in vitro.
PMID: 28004111
Ref: MeCP2 Promotes Gastric Cancer Progression Through Regulating FOXF1/Wnt5a/beta-Catenin and MYOD1/Caspase-3 Signaling Pathways.
PMID: 28131747
Ref: WNT5A Correlates with Clinicopathological Characteristics in Gastric Cancer: a Meta-Analysis.
PMID: 28135710
Ref: FBXO50 Enhances the Malignant Behavior of Gastric Cancer Cells.
PMID: 28560594
 Ref: Genomic predictors of chemotherapy efficacy in advanced or recurrent gastric cancer in the GC0301/TOP002 phase III clinical trial.
PMID: 29061504
Ref: The clinicopathological and prognostic significances of Dkk3 expression in cancers: A bioinformatics analysis.
PMID: 29843219
Ref: Characteristics and predictors of gastric cancer after Helicobacter pylori eradication.
PMID: 29853734