Primary Site >> Colorectal Cancer
Gene >> VEGFC
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Ref: Vegf, Vegf-B, Vegf-C and their receptors KDR, FLT-1 and FLT-4 during the neoplastic progression of human colonic mucosa. PMID: 10738243 Ref: Vascular endothelial growth factor-C (VEGF-C) expression in human colorectal cancer tissues. PMID: 10970690 |
Ref: VEGF-A, VEGF-C, and VEGF-D in colorectal cancer progression. PMID: 11687953 |
Ref: Clinical significance of vascular endothelial growth factor C expression and angiogenesis at the deepest invasive site of advanced colorectal carcinoma. PMID: 11914602 Ref: Expression of the vascular endothelial growth factor receptor-3 (VEGFR-3) and its ligand VEGF-C in human colorectal adenocarcinoma. PMID: 12168824 |
Ref: Clinical significance of angiogenic factor expression at the deepest invasive site of advanced colorectal carcinoma. PMID: 12457033 Ref: Immunodetection and molecular forms of plasma vascular endothelial growth factor-C. PMID: 12527932 Ref: Quantification of vascular endothelial growth factor-C and its receptor-3 messenger RNA with real-time quantitative polymerase chain reaction as a predictor of lymph node metastasis in human colorectal cancer. PMID: 12660643 Ref: c-MET expression level in primary colon cancer: a predictor of tumor invasion and lymph node metastases. PMID: 12684423 Ref: The angiogenic switch for vascular endothelial growth factor (VEGF)-A, VEGF-B, VEGF-C, and VEGF-D in the adenoma-carcinoma sequence during colorectal cancer progression. PMID: 12754739 Ref: The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis. PMID: 12782675 Ref: Lymphagenesis correlates with expression of vascular endothelial growth factor-C in colorectal cancer. PMID: 12792749 Ref: Quantitative analysis of lymphangiogenic markers in human colorectal cancer. PMID: 12851706 Ref: Expression analysis of vascular endothelial growth factors and their relationships to lymph node metastasis in human colorectal cancer. PMID: 12866573 Ref: Vascular endothelial growth factors C and D and lymphangiogenesis in gastrointestinal tract malignancy. PMID: 12888807 Ref: Correlation between vascular endothelial growth factor C expression and lymph node metastasis in T1 carcinoma of the colon and rectum. PMID: 14513319 |
Ref: Expression of VEGF-C and VEGF-D at the invasive edge correlates with lymph node metastasis and prognosis of patients with colorectal carcinoma. PMID: 14720324 Ref: Expression pattern of vascular endothelial growth factor-C in human colorectal normal mucosa and neoplastic mucosa. PMID: 15086167 Ref: Regulation of vascular endothelial growth factor (VEGF)-C and VEGF-D expression by the organ microenvironment in human colon carcinoma. PMID: 15196547 Ref: Expression of vascular endothelial growth factor-C and the relationship between lymphangiogenesis and lymphatic metastasis in colorectal cancer. PMID: 15484296 Ref: Expression of vascular endothelial growth factor C and its correlation with lymph node metastasis in colorectal carcinoma. PMID: 15791852 Ref: (86)Y-CHX-A''-Diethylenetriamine pentaacetic acid-bevacizumab PMID: 21433411 Ref: (64)Cu-1,4,7-Triazacyclononane-1,4,7-triacetic acid-p-isothiocyanatobenzyl-bevacizumab-IRDye 800CW PMID: 23534080 |
Ref: The lymphangiogenic vascular endothelial growth factors VEGF-C and -D are ligands for the integrin alpha9beta1. PMID: 15590642 Ref: Vascular endothelial growth factor C promotes lymph node metastasis in a rectal cancer orthotopic model. PMID: 15674494 Ref: Clinical significance of nuclear morphometry at the invasive front of T1 colorectal cancer and relation to expression of VEGF-A and VEGF-C. PMID: 16015039 Ref: Pre-operative plasma levels of vascular endothelial growth factor A, C and D in patients with colorectal cancer. PMID: 16097569 Ref: [Correlation of lymphangiogenesis to progression of colorectal cancer]. PMID: 16219148 Ref: [Relationship of vascular endothelial growth factor-C and lymphangiogenesis with the development and prognosis of colon cancer]. PMID: 16299655 |
Ref: Impact of laparotomy and liver resection on the peritoneal concentrations of fibroblast growth factor 2, vascular endothelial growth factor and hepatocyte growth factor. PMID: 16249905 Ref: Vascular endothelial growth factors and receptors in colorectal cancer: implications for anti-angiogenic therapy. PMID: 16321517 Ref: Coexpression of VEGF-C and Cox-2 in human colorectal cancer and its association with lymph node metastasis. PMID: 16474989 Ref: The relationship between MSI status and vessel density in colorectal carcinoma. PMID: 16739879 Ref: Serum vascular endothelial growth factor-C and vascular endothelial growth factor level in patients with colorectal carcinoma and clinical significance. PMID: 16961284 Ref: [Clinical significance of detection on lymphatic microvessel, lymphatic microvessel density and vascular endothelial growth factor-C in patients with colorectal carcinoma]. PMID: 17143789 Ref: Association between expression of vascular endothelial growth factor C, chemokine receptor CXCR4 and lymph node metastasis in colorectal cancer. PMID: 17641542 |
Ref: Vascular endothelial growth factor-C (VEGF-C) is a more specific risk factor for lymph node metastasis than VEGF-D in submucosal colorectal cancer. PMID: 17419234 Ref: Vascular endothelial growth factors C and D represent novel prognostic markers in colorectal carcinoma using quantitative image analysis. PMID: 17446709 Ref: Predictive value of vascular endothelial growth factor-C expression for local recurrence of rectal carcinoma. PMID: 17487386 Ref: A novel in vitro model of lymphatic metastasis from colorectal cancer. PMID: 17640671 Ref: Clinical impact of matrix metalloproteinase-7 mRNA expression in the invasive front and inner surface of tumor tissues in patients with colorectal cancer. PMID: 17676380 Ref: [The role of immune system in colon metastasis. Lymphangiogenesis or lymphedema in cancer tissue]. PMID: 17679395 Ref: [The expression of vascular endothelial growth factor C, ETS-1, microvessal density, and microlymphaticdensity and their clinicopathologic in colorectal carcinoma]. PMID: 17706142 Ref: Correlations between cyclooxygenase-2 expression and angiogenic factors in primary tumors and liver metastases in colorectal cancer. PMID: 17846040 Ref: Lymphatic vessel density, microvessel density and lymphangiogenic growth factor expression in colorectal cancer. PMID: 17931169 |
Ref: Distributions of angiogenesis and lymphangiogenesis in gastrointestinal intramucosal tumors. PMID: 18202892 Ref: Hypoxia-induced epithelial VEGF-C/VEGFR-3 upregulation in carcinoma cell lines. PMID: 18292935 Ref: Vector-based RNA interference against vascular endothelial growth factor-C inhibits tumor lymphangiogenesis and growth of colorectal cancer in vivo in mice. PMID: 18364118 Ref: Circulating lymphangiogenic growth factors in gastrointestinal solid tumors, could they be of any clinical significance? PMID: 18461654 Ref: Modification of the primary tumor microenvironment by transforming growth factor alpha-epidermal growth factor receptor signaling promotes metastasis in an orthotopic colon cancer model. PMID: 18583324 Ref: VEGF-D expression correlates with colorectal cancer aggressiveness and is downregulated by cetuximab. PMID: 18636661 Ref: Effect of chemotherapeutic stress on induction of vascular endothelial growth factor family members and receptors in human colorectal cancer cells. PMID: 18790786 Ref: Clinical significance of plasma level of vascular endothelial growth factor-C in patients with colorectal cancer. PMID: 18923001 Ref: Sialyl Lewis X expression and lymphatic microvessel density in primary tumors of node-negative colorectal cancer patients predict disease recurrence. PMID: 19308692 |
Ref: Association between EGF, TGF-beta1, VEGF gene polymorphism and colorectal cancer. PMID: 19011936 Ref: Preoperative serum levels of serum VEGF-C is associated with distant metastasis in colorectal cancer patients. PMID: 19084972 Ref: Mechanisms of lymphatic metastasis in human colorectal adenocarcinoma. PMID: 19253334 Ref: Expression of Tiam1 and VEGF-C correlates with lymphangiogenesis in human colorectal carcinoma. PMID: 19276682 Ref: Vascular endothelial growth factor-C siRNA delivered via calcium carbonate nanoparticle effectively inhibits lymphangiogenesis and growth of colorectal cancer in vivo. PMID: 19409048 |
Ref: Irinotecan and colorectal cancer: the role of p53, VEGF-C and alpha-B-crystallin expression. PMID: 20012297 Ref: Role of the VEGF ligand to receptor ratio in the progression of mismatch repair-proficient colorectal cancer. PMID: 20222950 Ref: Elevated IGFIR expression regulating VEGF and VEGF-C predicts lymph node metastasis in human colorectal cancer. PMID: 20459642 Ref: [Expression and significance of RECK, metalloproteinase-9 and vascular endothelial growth factor-C in colorectal cancer]. PMID: 20878580 Ref: The relationship among acute-phase response proteins, cytokines and hormones in cachectic patients with colon cancer. PMID: 20920199 |
Ref: Vascular endothelial growth factor-A and -C: expression and correlations with lymphatic metastasis and prognosis in colorectal cancer. PMID: 20107934 Ref: Immunohistochemical analysis of vascular density and area in colorectal carcinoma using different markers and comparison with clinicopathologic prognostic factors. PMID: 21222066 Ref: Metastasis-associated protein 1 induces VEGF-C and facilitates lymphangiogenesis in colorectal cancer. PMID: 21448429 Ref: Roles of VEGF-C and Smad4 in the lymphangiogenesis, lymphatic metastasis, and prognosis in colon cancer. PMID: 21786062 Ref: Comparison of lymphangiogenesis between primary colorectal cancer and corresponding liver metastases. PMID: 22199337 Ref: Serum vascular endothelial growth factor-C and lymphoangiogenesis are associated with the lymph node metastasis and prognosis of patients with colorectal cancer. PMID: 22295309 Ref: Cellular signal transduction pathways by leptin in colorectal cancer tissue: preliminary results. PMID: 22363883 |
Ref: The relationship among acute-phase responce proteins, cytokines, and hormones in various gastrointestinal cancer types patients with cachectic. PMID: 21803781 Ref: Downregulation of VEGF-C expression in lung and colon cancer cells decelerates tumor growth and inhibits metastasis via multiple mechanisms. PMID: 21804602 Ref: Recombinant canstatin inhibits angiopoietin-1-induced angiogenesis and lymphangiogenesis. PMID: 21823121 Ref: Correlations between SUVmax and expression of GLUT1 and growth factors inducing lymphangiogenesis. PMID: 22444673 Ref: The extra domain A of fibronectin increases VEGF-C expression in colorectal carcinoma involving the PI3K/AKT signaling pathway. PMID: 22496919 Ref: Negative regulation of cell motile and invasive activities by lysophosphatidic acid receptor-3 in colon cancer HCT116 cells. PMID: 22763559 Ref: Clinical procedure for colon carcinoma tissue sampling directly affects the cancer marker-capacity of VEGF family members. PMID: 23148666 Ref: Relationship between expression and prognostic ability of PTEN, STAT3 and VEGF-C in colorectal cancer. PMID: 23170117 |
Ref: Tropomyosin receptor kinases B and C are tumor progressive and metastatic marker in colorectal carcinoma. PMID: 23332094 Ref: Expression of GLI1 correlates with expression of lymphangiogenesis proteins, vascular endothelial growth factor C and vascular endothelial growth factor receptor 3, in colorectal cancer. PMID: 23336661 Ref: miRNA-27b targets vascular endothelial growth factor C to inhibit tumor progression and angiogenesis in colorectal cancer. PMID: 23593282 Ref: Clinicopathological correlation and prognostic significance of VEGF-A, VEGF-C, VEGFR-2 and VEGFR-3 expression in colorectal cancer. PMID: 23603341 Ref: [Effect of vascular endothelial growth factor C and collagen triple helix repeat containing 1 expression on prognosis of rectal carcinoma patients]. PMID: 23888454 Ref: New molecular staging with G-factors (VEGF-C and Reg IV) by supplementing TNM classification in colorectal cancers. PMID: 24101199 Ref: [Expression and clinical significance of vascular endothelial growth factor-C and nm23-H1 in stage II and III colorectal carcinomas]. PMID: 24119904 |
Ref: VEGF-C and VEGF-D overexpression is more common in left-sided and well-differentiated colon adenocarcinoma. PMID: 24173916 Ref: Epithelial membrane protein 1 negatively regulates cell growth and metastasis in colorectal carcinoma. PMID: 24744589 Ref: Effect of thoracic epidural anaesthesia on serum vascular endothelial growth factor C and cytokines in patients undergoing anaesthesia and surgery for colon cancer. PMID: 24966150 Ref: Possible involvement of tumor-producing VEGF-A in the recruitment of lymphatic endothelial progenitor cells from bone marrow. PMID: 25242215 Ref: MMP-11 and VEGF-C expression correlate with clinical features of colorectal adenocarcinoma. PMID: 25356153 |
Ref: Metastasis-associated in colon cancer-1 upregulates vascular endothelial growth factor-C/D to promote lymphangiogenesis in human gastric cancer. PMID: 25444928 Ref: Neuropilin-2 mediates lymphangiogenesis of colorectal carcinoma via a VEGFC/VEGFR3 independent signaling. PMID: 25543087 Ref: Smad4 acts as tumor suppressor by antagonizing lymphangiogenesis in colorectal cancer. PMID: 25680269 Ref: Vascular endothelial growth factor C disrupts the endothelial lymphatic barrier to promote colorectal cancer invasion. PMID: 25754161 Ref: The relevance of cell type- and tumor zone-specific VEGFR-2 activation in locally advanced colon cancer. PMID: 25967108 Ref: High-mobility group box 1 protein activating nuclear factor-kappaB to upregulate vascular endothelial growth factor C is involved in lymphangiogenesis and lymphatic node metastasis in colon cancer. PMID: 26001393 Ref: Paracrine factors from adipose-mesenchymal stem cells enhance metastatic capacity through Wnt signaling pathway in a colon cancer cell co-culture model. PMID: 26060426 Ref: Vascular endothelial growth factor D expression is a potential biomarker of bevacizumab benefit in colorectal cancer. PMID: 26125443 Ref: MTA1 Is Up-regulated in Colorectal Cancer and Is Inversely Correlated with Lymphatic Metastasis. PMID: 26543080 Ref: Impact of prospero homeobox-1 on tumor cell behavior and prognosis in colorectal cancer. PMID: 26807311 Ref: VEGF-C expression is not a prognostic factor in locally advanced colon adenocarcinoma. PMID: 26843840 |
Ref: Comparison of (18)F-fluorodeoxyglucose PET/CT findings with vascular endothelial growth factors and receptors in colorectal cancer. PMID: 26476536 Ref: Impact of KITENIN on tumor angiogenesis and lymphangiogenesis in colorectal cancer. PMID: 26496979 Ref: Integrin alpha4 Induces Lymphangiogenesis and Metastasis via Upregulation of VEGF-C in Human Colon Cancer. PMID: 26917449 Ref: Novel anti-angiogenic therapeutic strategies in colorectal cancer. PMID: 26938715 Ref: Effect of Recepteur d'Origine Nantais expression on chemosensitivity and tumor cell behavior in colorectal cancer. PMID: 27035413 Ref: Angiogenesis genotyping and clinical outcome during regorafenib treatment in metastatic colorectal cancer patients. PMID: 27117754 Ref: BRG1 targeting STAT3/VEGFC signaling regulates lymphangiogenesis in colorectal cancer. PMID: 27145366 Ref: Prognostic significance of VEGF-C immunohistochemical expression in colorectal cancer: A meta-analysis. PMID: 27155587 Ref: High expression of WISP1 in colon cancer is associated with apoptosis, invasion and poor prognosis. PMID: 27409174 Ref: Metastasis-associated in colon cancer-1 in gastric cancer: Beyond metastasis. PMID: 27547006 Ref: Pien Tze Huang suppresses VEGF-C-mediated lymphangiogenesis in colorectal cancer. PMID: 27779683 Ref: Expression analysis and clinical significance of eIF4E, VEGF-C, E-cadherin and MMP-2 in colorectal adenocarcinoma. PMID: 27907907 |
Ref: TBL1XR1 predicts isolated tumor cells and micrometastasis in patients with TNM stage I/II colorectal cancer. PMID: 28127799 Ref: Immunotherapy for the treatment of colorectal tumors: focus on approved and in-clinical-trial monoclonal antibodies. PMID: 28138221 Ref: Colorectal polypoid lesions and expression of vascular endothelial growth factor in a consecutive series of endoscopic and surgical patients. PMID: 28347226 Ref: Smad4 Inhibits VEGF-A and VEGF-C Expressions via Enhancing Smad3 Phosphorylation in Colon Cancer. PMID: 28445620 Ref: Next-generation sequencing reveals lymph node metastasis associated genetic markers in colorectal cancer. PMID: 28672935 Ref: Lymphangiogenic Gene Expression Is Associated With Lymph Node Recurrence and Poor Prognosis After Partial Hepatectomy for Colorectal Liver Metastasis. PMID: 28742689 |
Ref: miR-144 inhibits growth and metastasis of cervical cancer cells by targeting VEGFA and VEGFC. PMID: 29387205 Ref: VEGF pathway-targeting drugs induce evasive adaptation by activation of neuropilin-1/cMet in colon cancer cells. PMID: 29532881 Ref: VEGF-C in rectal cancer tissues promotes tumor invasion and metastasis. PMID: 29552758 Ref: Prognostic Value of ACVRL1 Expression in Metastatic Colorectal Cancer Patients Receiving First-line Chemotherapy With Bevacizumab: Results From the Triplet Plus Bevacizumab (TRIBE) Study. PMID: 29636300 Ref: Association Between c-Met and Lymphangiogenic Factors in Patients With Colorectal Cancer. PMID: 29742856 Ref: Association Between Hypoxia-Inducible Factor-2alpha (HIF-2alpha) Expression and Colorectal Cancer and Its Prognostic Role: a Systematic Analysis. PMID: 30021192 Ref: Analyzing the molecular mechanism of the tissue specificity of gastrointestinal stromal tumors by using bioinformatics approaches. PMID: 30358224 |