Primary Site >> Colorectal Cancer
Gene >> VDR
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Ref: Characterization of the vitamin D receptor from the Caco-2 human colon carcinoma cell line: effect of cellular differentiation. PMID: 1654769 Ref: Sex steroid and 1,25-dihydroxyvitamin D3 receptors in human colorectal adenocarcinoma and normal mucosa. PMID: 1847660 |
Ref: Regulation of vitamin D receptor abundance and responsiveness during differentiation of HT-29 human colon cancer cells. PMID: 8384998 |
Ref: Vitamin D receptors in breast cancer cells. PMID: 7881099 Ref: 1,25-dihydroxyvitamin D3 receptors in normal and malignant human colorectal tissues. PMID: 7954357 |
Ref: Growth control of human colon-adenocarcinoma-derived Caco-2 cells by vitamin-D compounds and extracellular calcium in vitro: relation to c-myc-oncogene and vitamin-D-receptor expression. PMID: 7558419 Ref: Growth regulation of human colon adenocarcinoma-derived cells by calcium, vitamin D and epidermal growth factor. PMID: 7602383 |
Ref: Antiproliferative responses to two human colon cancer cell lines to vitamin D3 are differently modified by 9-cis-retinoic acid. PMID: 8564982 Ref: Vitamin D receptor and cytokeratin expression may be progression indicators in human colon cancer. PMID: 8694565 |
Ref: Vitamin D receptor expression as a predictive marker of biological behavior in human colorectal cancer. PMID: 9676831 Ref: [Molecular effects of vitamin D on cell cycle and oncogenesis]. PMID: 9691832 |
Ref: Novel 19-nor-hexafluoride vitamin D3 analog (Ro 25-6760) inhibits human colon cancer in vitro via apoptosis. PMID: 10200351 Ref: The protective effect of estrogen against chemically induced murine colon carcinogenesis is associated with decreased CpG island methylation and increased mRNA and protein expression of the colonic vitamin D receptor. PMID: 10691027 |
Ref: Vitamin D receptor gene BsmI polymorphism correlates with erbB-2/HER-2 expression in human rectal cancer. PMID: 10765127 |
Ref: The Wilms' tumor gene product (WT1) modulates the response to 1,25-dihydroxyvitamin D3 by induction of the vitamin D receptor. PMID: 11050081 Ref: 25-Hydroxyvitamin D(3)-1alpha-hydroxylase and vitamin D receptor gene expression in human colonic mucosa is elevated during early cancerogenesis. PMID: 11179736 Ref: 1,25-Dihydroxycholecalciferol enhances butyrate-induced p21(Waf1/Cip1) expression. PMID: 11322770 Ref: Transcriptional regulation of the vitamin D(3) receptor gene by ZEB. PMID: 11432806 Ref: Variants of the VDR gene and risk of colon cancer (United States). PMID: 11456232 Ref: Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. PMID: 11470825 Ref: MCF-7/VD(R): a new vitamin D resistant cell line. PMID: 11500919 Ref: Oestrogen and vitamin D receptor (VDR) genotypes and the expression of ErbB-2 and EGF receptor in human rectal cancers. PMID: 11506951 Ref: Isolation, identification and biological activity of 24R,25-dihydroxy-3-epi-vitamin D3: a novel metabolite of 24R,25-dihydroxyvitamin D3 produced in rat osteosarcoma cells (UMR 106). PMID: 11508700 Ref: Characterization of a vitamin D receptor knockout mouse as a model of colorectal hyperproliferation and DNA damage. PMID: 11532865 Ref: Butyrate-induced differentiation of Caco-2 cells is mediated by vitamin D receptor. PMID: 11676498 |
Ref: Colonic epithelial cell proliferation decreases with increasing levels of serum 25-hydroxy vitamin D. PMID: 11815408 Ref: Vitamin D receptor as an intestinal bile acid sensor. PMID: 12016314 Ref: Clonal differences in expression of 25-hydroxyvitamin D(3)-1alpha-hydroxylase, of 25-hydroxyvitamin D(3)-24-hydroxylase, and of the vitamin D receptor in human colon carcinoma cells: effects of epidermal growth factor and 1alpha,25-dihydroxyvitamin D(3). PMID: 12027461 Ref: Vitamin D receptor activity and prevention of colonic hyperproliferation and oxidative stress. PMID: 12067583 Ref: Liganded VDR induces CYP3A4 in small intestinal and colon cancer cells via DR3 and ER6 vitamin D responsive elements. PMID: 12470639 |
Ref: Vitamin D receptor start codon polymorphism and colorectal cancer risk: effect modification by dietary calcium and fat in Singapore Chinese. PMID: 12807755 Ref: Vitamin D2 analog 19-nor-1,25-dihydroxyvitamin D2: antitumor activity against leukemia, myeloma, and colon cancer cells. PMID: 12813173 Ref: Short-chain fatty acids and colon cancer cells: the vitamin D receptor--butyrate connection. PMID: 12899527 Ref: Phytoestrogens and 17beta-estradiol influence vitamin D metabolism and receptor expression-relevance for colon cancer prevention. PMID: 12899537 Ref: Regulation of extrarenal vitamin D metabolism as a tool for colon and prostate cancer prevention. PMID: 12899539 Ref: The first locked side-chain analogues of calcitriol (1alpha,25-dihydroxyvitamin D3) induce vitamin D receptor transcriptional activity. PMID: 14572242 |
Ref: p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor. PMID: 15037631 Ref: Aspirin, NSAIDs, and colorectal cancer: possible involvement in an insulin-related pathway. PMID: 15066917 Ref: Circulating vitamin D metabolites, polymorphism in vitamin D receptor, and colorectal adenoma risk. PMID: 15066918 Ref: C-jun N-terminal kinase modulates 1,25-dihydroxyvitamin D3-induced cytochrome P450 3A4 gene expression. PMID: 15205382 Ref: Ligand modulates VDR-Ser/Thr protein phosphatase interaction and p70S6 kinase phosphorylation in a cell-context-dependent manner. PMID: 15225771 Ref: Dietary calcium, vitamin D, VDR genotypes and colorectal cancer. PMID: 15252846 Ref: The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer. PMID: 15322538 Ref: Loss of CYP3A7 gene induction by 1,25-dihydroxyvitamin D3 is caused by less binding of VDR to the proximal ER6 in CYP3A7 gene. PMID: 15358113 Ref: p38 MAPK signaling pathway is involved in butyrate-induced vitamin D receptor expression. PMID: 15504345 Ref: Associations between BMI, energy intake, energy expenditure, VDR genotype and colon and rectal cancers (United States). PMID: 15577288 |
Ref: Molecular and functional comparison of 1,25-dihydroxyvitamin D(3) and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4. PMID: 15578590 Ref: SNAIL vs vitamin D receptor expression in colon cancer: therapeutics implications. PMID: 15770204 Ref: Colon-specific regulation of vitamin D hydroxylases--a possible approach for tumor prevention. PMID: 15905206 Ref: Regulation of vitamin D receptor expression via estrogen-induced activation of the ERK 1/2 signaling pathway in colon and breast cancer cells. PMID: 15930183 Ref: Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3. PMID: 15985530 Ref: Promoter-, cell-, and ligand-specific transactivation responses of the VDRB1 isoform. PMID: 15992766 Ref: Chemoprevention of chemically-induced mammary and colon carcinogenesis by 1alpha-hydroxyvitamin D5. PMID: 16051482 Ref: Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Wnt you like to know? PMID: 16126938 Ref: Correlation between VDR expression and antiproliferative activity of vitamin D3 compounds in combination with cytostatics. PMID: 16158969 Ref: Vitamin D deficiency enhances the growth of MC-26 colon cancer xenografts in Balb/c mice. PMID: 16177194 Ref: E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer: clinicopathological correlations. PMID: 16203744 Ref: Expression of vitamin D receptor and 25-hydroxyvitamin D3-1{alpha}-hydroxylase in normal and malignant human colon. PMID: 16214919 |
Ref: Start codon polymorphisms in the vitamin D receptor and colorectal cancer risk. PMID: 16019132 Ref: Expression of VDR and CYP24A1 mRNA in human tumors. PMID: 16180015 Ref: Associations between vitamin D, vitamin D receptor gene and the androgen receptor gene with colon and rectal cancer. PMID: 16425262 Ref: PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States). PMID: 16489531 Ref: Functional role of VDR in the activation of p27Kip1 by the VDR/Sp1 complex. PMID: 16518840 Ref: Haplotype analysis of common vitamin D receptor variants and colon and rectal cancers. PMID: 16614118 Ref: Comparative genome analysis identifies the vitamin D receptor gene as a direct target of p53-mediated transcriptional activation. PMID: 16651407 Ref: The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas. PMID: 16804902 Ref: Effects of 1alpha,25-dihydroxyvitamin D3 in human colon cancer cells. PMID: 16886677 Ref: The retinoid X receptor ligand restores defective signalling by the vitamin D receptor. PMID: 16936639 Ref: Vitamin D receptor gene polymorphisms, dietary promotion of insulin resistance, and colon and rectal cancer. PMID: 16965239 Ref: Phytoestrogens regulate transcription and translation of vitamin D receptor in colon cancer cells. PMID: 17088408 |
Ref: Vitamin D and estrogen receptor gene polymorphisms and the risk of colorectal cancer in Bulgaria. PMID: 16788818 Ref: Synergism between vitamin D and secreted protein acidic and rich in cysteine-induced apoptosis and growth inhibition results in increased susceptibility of therapy-resistant colorectal cancer cells to chemotherapy. PMID: 17237289 Ref: Investigation of the VDR gene polymorphisms association with susceptibility to colorectal cancer. PMID: 17243190 Ref: Chemopreventive efficacy of 25-hydroxyvitamin D3 in colon cancer. PMID: 17257827 Ref: The inhibition of Wnt/beta-catenin signalling by 1alpha,25-dihydroxyvitamin D3 is abrogated by Snail1 in human colon cancer cells. PMID: 17395983 Ref: The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells. PMID: 17449905 Ref: The TGFbeta/Smad 3-signaling pathway is involved in butyrate-mediated vitamin D receptor (VDR)-expression. PMID: 17471513 Ref: Involvement of different nuclear hormone receptors in butyrate-mediated inhibition of inducible NF kappa B signalling. PMID: 17521736 Ref: Lithocholic acid can carry out in vivo functions of vitamin D. PMID: 17535892 Ref: IL6 genotypes and colon and rectal cancer. PMID: 17694420 Ref: CDX2 VDR polymorphism and colorectal cancer. PMID: 18086783 Ref: Vitamin D receptor: key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligands. PMID: 18290715 |
Ref: Association of familial colorectal cancer with variants in the E-cadherin (CDH1) and cyclin D1 (CCND1) genes. PMID: 17960397 Ref: Leptin and leptin receptor genotypes and colon cancer: gene-gene and gene-lifestyle interactions. PMID: 18059035 Ref: DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3. PMID: 18408752 Ref: Lithocholic acid down-regulation of NF-kappaB activity through vitamin D receptor in colonic cancer cells. PMID: 18515093 Ref: [Polymorphism of vitamin D receptor Fok I and colorectal cancer risk in Chinese]. PMID: 18544842 Ref: Vitamin D receptor levels in colorectal cancer. Possible role of BsmI polymorphism. PMID: 18583126 Ref: Association of vitamin D receptor gene variants, adiposity and colon cancer. PMID: 18628249 Ref: Modification of the inverse association between dietary vitamin D intake and colorectal cancer risk by a FokI variant supports a chemoprotective action of Vitamin D intake mediated through VDR binding. PMID: 18709640 Ref: A novel SNP in a vitamin D response element of the CYP24A1 promoter reduces protein binding, transactivation, and gene expression. PMID: 18824104 Ref: Genetic variation in calcium-sensing receptor and risk for colon cancer. PMID: 18843020 Ref: Superagonistic fluorinated vitamin D3 analogs stabilize helix 12 of the vitamin D receptor. PMID: 18940664 Ref: RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells. PMID: 19015318 Ref: Vitamin D and Wnt/beta-catenin pathway in colon cancer: role and regulation of DICKKOPF genes. PMID: 19035286 |
Ref: Vitamin D receptor gene polymorphisms and the risk of colorectal cancer in a Chinese population. PMID: 18618252 Ref: Medical treatment of primary sclerosing cholangitis: a role for novel bile acids and other (post-)transcriptional modulators? PMID: 18751930 Ref: Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways. PMID: 18992263 Ref: Vitamin D receptor poly(A) microsatellite and colorectal cancer risk in Caucasians. PMID: 19052755 Ref: Chemoprevention of colorectal neoplasia by estrogen: potential role of vitamin D activity. PMID: 19139017 Ref: Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer. PMID: 19502595 Ref: Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells. PMID: 19662683 Ref: The relevance of vitamin D receptor (VDR) gene polymorphisms for cancer: a review of the literature. PMID: 19667145 Ref: Parallel elevation of colonic 1,25-dihydroxyvitamin D3 levels and apoptosis in female mice on a calcium-deficient diet. PMID: 19667171 Ref: Vitamin D receptor and calcium sensing receptor polymorphisms and the risk of colorectal cancer in European populations. PMID: 19706842 Ref: Vitamin D related genes, CYP24A1 and CYP27B1, and colon cancer risk. PMID: 19706847 Ref: Vitamin D receptor expression is associated with colon cancer in ulcerative colitis. PMID: 19787215 Ref: Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer. PMID: 19789368 Ref: SNAI1 expression in colon cancer related with CDH1 and VDR downregulation in normal adjacent tissue. PMID: 19802011 Ref: Control of TCF-4 expression by VDR and vitamin D in the mouse mammary gland and colorectal cancer cell lines. PMID: 19924301 |
Ref: Vitamin D receptor gene ApaI polymorphism is associated with susceptibility to colorectal cancer. PMID: 19795209 Ref: Vitamin D receptor ligands, adenomatous polyposis coli, and the vitamin D receptor FokI polymorphism collectively modulate beta-catenin activity in colon cancer cells. PMID: 20043299 Ref: Genetic variation in the vitamin D receptor (VDR) and the vitamin D-binding protein (GC) and risk for colorectal cancer: results from the Colon Cancer Family Registry. PMID: 20086113 Ref: CD-ring modified vitamin D3 analogs and their superagonistic action. PMID: 20132886 Ref: The transcription factors Snail1 and Snail2 repress vitamin D receptor during colon cancer progression. PMID: 20138990 Ref: Genetic polymorphisms in vitamin D receptor VDR/RXRA influence the likelihood of colon adenoma recurrence. PMID: 20145122 Ref: Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention. PMID: 20153625 Ref: The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging. PMID: 20227497 Ref: Calcium, vitamin D, VDR genotypes, and epigenetic and genetic changes in rectal tumors. PMID: 20432164 Ref: Genetic variation in the retinoid X receptor and calcium-sensing receptor and risk of colorectal cancer in the Colon Cancer Family Registry. PMID: 20558521 |
Ref: Variation in the vitamin D receptor gene is not associated with risk of colorectal cancer in the Czech Republic. PMID: 20585998 Ref: A randomized clinical trial of the effects of supplemental calcium and vitamin D3 on markers of their metabolism in normal mucosa of colorectal adenoma patients. PMID: 21084270 Ref: Start codon FokI and intron 8 BsmI variants in the vitamin D receptor gene and susceptibility to colorectal cancer. PMID: 21132374 Ref: Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells. PMID: 21342487 Ref: Meta-analyses of vitamin D intake, 25-hydroxyvitamin D status, vitamin D receptor polymorphisms, and colorectal cancer risk. PMID: 21378269 Ref: Approaches to neural stem cells and cancer cells based on natural products. PMID: 21467667 Ref: Phosphatidylinositol 5-phosphate 4-kinase type II beta is required for vitamin D receptor-dependent E-cadherin expression in SW480 cells. PMID: 21514270 Ref: Colonic vitamin D metabolism: implications for the pathogenesis of inflammatory bowel disease and colorectal cancer. PMID: 21801808 Ref: Case-control study for colorectal cancer genetic susceptibility in EPICOLON: previously identified variants and mucins. PMID: 21819567 Ref: Prognostic role of vitamin d status and efficacy of vitamin D supplementation in cancer patients: a systematic review. PMID: 21835895 Ref: Vitamin D receptor deficiency enhances Wnt/beta-catenin signaling and tumor burden in colon cancer. PMID: 21858154 Ref: KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells. PMID: 21890490 Ref: Pretreatment with the probiotic VSL#3 delays transition from inflammation to dysplasia in a rat model of colitis-associated cancer. PMID: 21903764 Ref: Genetic associations in the vitamin D receptor and colorectal cancer in African Americans and Caucasians. PMID: 22046258 |
Ref: Inactivation of the vitamin D receptor in APC(min/+) mice reveals a critical role for the vitamin D receptor in intestinal tumor growth. PMID: 21328347 Ref: Mechanism of action of vitamin D and the vitamin D receptor in colorectal cancer prevention and treatment. PMID: 21861107 Ref: Regulation of CYP24 splicing by 1,25-dihydroxyvitamin D(3) in human colon cancer cells. PMID: 22068926 Ref: VDR/RXR and TCF4/beta-catenin cistromes in colonic cells of colorectal tumor origin: impact on c-FOS and c-MYC gene expression. PMID: 22108803 Ref: The -4817 G>A (rs2238136) variant of the vitamin D receptor gene: a probable risk factor for colorectal cancer. PMID: 22167329 Ref: Prediagnostic 25-hydroxyvitamin D, VDR and CASR polymorphisms, and survival in patients with colorectal cancer in western European ppulations. PMID: 22278364 Ref: MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells. PMID: 22328083 Ref: Vitamin D receptor gene polymorphisms and colorectal cancer risk: a systematic meta-analysis. PMID: 22529698 Ref: Clinicopathologic correlation of vitamin D receptor expression with retinoid X receptor and MIB-1 expression in primary and metastatic osteosarcoma. PMID: 22542077 Ref: Vitamin D receptor polymorphisms in colorectal cancer in New Zealand: an association study. PMID: 22729058 Ref: Association of vitamin D receptor gene polymorphisms with colon cancer. PMID: 22852885 Ref: Using components of the vitamin D pathway to prevent and treat colon cancer. PMID: 23206285 Ref: The Vitamin D Receptor, Inflammatory Bowel Diseases, and Colon Cancer. PMID: 23814529 Ref: Relative Expression of Vitamin D Hydroxylases, CYP27B1 and CYP24A1, and of Cyclooxygenase-2 and Heterogeneity of Human Colorectal Cancer in Relation to Age, Gender, Tumor Location, and Malignancy: Results from Factor and Cluster Analysis. PMID: 24213465 |
Ref: Inhibition of cancer growth and induction of apoptosis by BGP-13 and BGP-15, new calcipotriene-derived vitamin D3 analogs, in-vitro and in-vivo studies. PMID: 22661288 Ref: Curcumin induces human cathelicidin antimicrobial peptide gene expression through a vitamin D receptor-independent pathway. PMID: 22841393 Ref: Epigenetic regulation of the 1,25-dihydroxyvitamin D3 24-hydroxylase (CYP24A1) in colon cancer cells. PMID: 22940288 Ref: Corepressors (NCoR and SMRT) as well as coactivators are recruited to positively regulated 1alpha,25-dihydroxyvitamin D3-responsive genes. PMID: 22944139 Ref: Vitamin D and breast cancer: emerging concepts. PMID: 23142286 Ref: Systematic review: diet-gene interactions and the risk of colorectal cancer. PMID: 23216531 Ref: Synthesis and biological evaluation of halogenated curcumin analogs as potential nuclear receptor selective agonists. PMID: 23276449 Ref: Calcium nutrition and extracellular calcium sensing: relevance for the pathogenesis of osteoporosis, cancer and cardiovascular diseases. PMID: 23340319 Ref: Combined colonic cancer treatment with vitamin D analogs and irinotecan or oxaliplatin. PMID: 23393334 Ref: CYP24A1 and CYP27B1 polymorphisms modulate vitamin D metabolism in colon cancer cells. PMID: 23423976 Ref: Role of STAT3 and vitamin D receptor in EZH2-mediated invasion of human colorectal cancer. PMID: 23424038 Ref: Serum vitamin D metabolites in colorectal cancer patients receiving cholecalciferol supplementation: correlation with polymorphisms in the vitamin D genes. PMID: 23456391 Ref: Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer. PMID: 23463632 Ref: Vitamin D receptor and retinoid X receptor alpha status and vitamin D insufficiency in models of murine colitis. PMID: 23585425 Ref: Evaluation of a possible direct effect by casein phosphopeptides on paracellular and vitamin D controlled transcellular calcium transport mechanisms in intestinal human HT-29 and Caco2 cell lines. PMID: 23681196 Ref: Vitamin D: beyond bone. PMID: 23682710 Ref: Vitamin D3 insufficiency and colorectal cancer. PMID: 23941729 Ref: Vitamin D receptor polymorphism and colorectal cancer-specific and all-cause mortality. PMID: 24075799 Ref: Genes and SNPs associated with non-hereditary and hereditary colorectal cancer. PMID: 24289550 Ref: Association of a VDR gene polymorphism with risk of colorectal cancer in Kashmir. PMID: 24289585 |
Ref: Vitamin D receptor FokI gene polymorphisms may be associated with colorectal cancer among African American and Hispanic participants. PMID: 24510435 Ref: Genetic variation in vitamin D-related genes and risk of colorectal cancer in African Americans. PMID: 24562971 Ref: Lack of associations between Vitamin D metabolism-related gene variants and risk of colorectal cancer. PMID: 24568525 Ref: Joint effects of colorectal cancer susceptibility loci, circulating 25-hydroxyvitamin D and risk of colorectal cancer. PMID: 24670869 Ref: Genome-wide (over)view on the actions of vitamin D. PMID: 24808867 Ref: Role of the VDR Bsm I and Apa I polymorphisms in the risk of colorectal cancer in Kashmir. PMID: 24903766 Ref: Vitamin D analogs combined with 5-fluorouracil in human HT-29 colon cancer treatment. PMID: 24919507 Ref: Predicted 25(OH)D score and colorectal cancer risk according to vitamin D receptor expression. PMID: 24920642 Ref: Vitamin D receptor BsmI polymorphism and colorectal cancer risk: an updated analysis. PMID: 24998544 Ref: Plasma vitamin D concentration influences survival outcome after a diagnosis of colorectal cancer. PMID: 25002714 Ref: MicroRNA-346 mediates tumor necrosis factor alpha-induced downregulation of gut epithelial vitamin D receptor in inflammatory bowel diseases. PMID: 25192497 Ref: Vitamin D receptor gene polymorphisms in relation to the risk of colorectal cancer in the Polish population. PMID: 25195132 Ref: The renin-angiotensin system mediates EGF receptor-vitamin d receptor cross-talk in colitis-associated colon cancer. PMID: 25212605 Ref: Association between circulating vitamin D, the Taq1 vitamin D receptor gene polymorphism and colorectal cancer risk among Jordanians. PMID: 25227839 Ref: The influence of the CHIEF pathway on colorectal cancer-specific mortality. PMID: 25541970 Ref: BsmI polymorphism of vitamin D receptor gene and cancer risk: a comprehensive meta-analysis. PMID: 25771722 |
Ref: The effect of 1,25 dihydroxyvitamin D3 treatment on the mRNA levels of beta catenin target genes in mice with colonic inactivation of both APC alleles. PMID: 25597951 Ref: Immunohistochemical expression of SP-NK-1R-EGFR pathway and VDR in colonic inflammation and neoplasia. PMID: 25684939 Ref: Associations between vitamin D receptor (VDR) gene polymorphisms and colorectal cancer risk and effect modifications of dietary calcium and vitamin D in a Japanese population. PMID: 25773805 Ref: Restoration of the anti-proliferative and anti-migratory effects of 1,25-dihydroxyvitamin D by silibinin in vitamin D-resistant colon cancer cells. PMID: 25846868 Ref: [Vitamin D, determinant of bone and extrabone health. Importance of vitamin D supplementation in milk and dairy products]. PMID: 25862325 Ref: Regulation of VDR Expression in Apc-Mutant Mice, Human Colon Cancers and Adenomas. PMID: 25873367 Ref: Associations of Probiotics with Vitamin D and Leptin Receptors and their Effects on Colon Cancer. PMID: 25987012 Ref: High prevalence of vitamin D deficiency and cancer in Saudi Arabian populations: Can we hypothesize a link? PMID: 26025591 Ref: p53 directly activates cystatin D/CST5 to mediate mesenchymal-epithelial transition: a possible link to tumor suppression by vitamin D3. PMID: 26158294 Ref: No Association Between Vitamin D Intake, VDR Polymorphisms, and Colorectal Cancer in a Population-Based Case-Control Study. PMID: 26224799 Ref: Differential antitumor effects of vitamin D analogues on colorectal carcinoma in culture. PMID: 26260259 Ref: Vitamin D, Cancer Risk, and Mortality. PMID: 26319903 |
Ref: Meta-analysis on vitamin D receptor and cancer risk: focus on the role of TaqI, ApaI, and Cdx2 polymorphisms. PMID: 25738688 Ref: Synthesis and evaluation of vitamin D receptor-mediated activities of cholesterol and vitamin D metabolites. PMID: 26774929 Ref: LRG1 modulates epithelial-mesenchymal transition and angiogenesis in colorectal cancer via HIF-1alpha activation. PMID: 26856989 Ref: Vitamin D Receptor Polymorphisms Relate to Risk of Adenomatous Polyps in a Sex-Specific Manner. PMID: 26904920 Ref: Computational Identification of Key Regulators in Two Different Colorectal Cancer Cell Lines. PMID: 27092172 Ref: c-Jun NH2-teminal kinase 1 interacts with vitamin D receptor and affects vitamin D-mediated inhibition of cancer cell proliferation. PMID: 27174721 Ref: The UVB1 Vitamin D analogue inhibits colorectal carcinoma progression. PMID: 27208626 Ref: Vitamin D and colorectal cancer: molecular, epidemiological and clinical evidence. PMID: 27245104 Ref: Association of Vitamin D Receptor Gene Polymorphisms with Colorectal Cancer in a Saudi Arabian Population. PMID: 27309378 Ref: Vitamin D Receptor Gene Polymorphism and the Risk of Colorectal Cancer: A Nested Case-Control Study. PMID: 27736940 Ref: A role for the vitamin D pathway in non-intestinal lesions in genetic and carcinogen models of colorectal cancer and in familial adenomatous polyposis. PMID: 27768599 Ref: Cross Talk between the Calcium-Sensing Receptor and the Vitamin D System in Prevention of Cancer. PMID: 27803671 |
Ref: Vitamin D receptor expression and associated gene signature in tumour stromal fibroblasts predict clinical outcome in colorectal cancer. PMID: 27053631 Ref: Vitamin D receptor is a novel transcriptional regulator for Axin1. PMID: 27601169 Ref: Vitamin D and the Epigenetic Machinery in Colon Cancer. PMID: 27855629 Ref: Control of Inflammatory Bowel Disease and Colorectal Cancer by Synthetic Vitamin D Receptor Ligands. PMID: 27915991 Ref: Genetic polymorphisms of vitamin D receptor (VDR), CYP27B1 and CYP24A1 genes and the risk of colorectal cancer. PMID: 28009432 Ref: Integrative genomic approaches to dissect clinically-significant relationships between the VDR cistrome and gene expression in primary colon cancer. PMID: 28027912 Ref: Vitamin D Reduces Colitis- and Inflammation-Associated Colorectal Cancer in Mice Independent of NOD2. PMID: 28045548 Ref: Constitutively active RAS signaling reduces 1,25 dihydroxyvitamin D-mediated gene transcription in intestinal epithelial cells by reducing vitamin D receptor expression. PMID: 28104492 Ref: H19 Overexpression Induces Resistance to 1,25(OH)2D3 by Targeting VDR Through miR-675-5p in Colon Cancer Cells. PMID: 28189050 Ref: Immune Modulation by Vitamin D: Special Emphasis on Its Role in Prevention and Treatment of Cancer. PMID: 28431765 Ref: Genetic polymorphisms of vitamin D metabolism genes and serum level of vitamin D in colorectal cancer. PMID: 28665452 Ref: Vitamin D receptor and calcium-sensing receptor polymorphisms and colorectal cancer survival in the Newfoundland population. PMID: 28765616 Ref: Investigation of Vitamin D Receptor Gene Polymorphism in Pediatric Patients with Brain Cancer. PMID: 28900319 Ref: Apolipoprotein M increases the expression of vitamin D receptor mRNA in colorectal cancer cells detected with duplex fluorescence reverse transcription-quantitative polymerase chain reaction. PMID: 29067439 Ref: Immunohystochemical Expression of Vitamin D Receptor in Development Stages of Colorectal Carcinoma. PMID: 29278636 |
Ref: Vitamin D in esophageal cancer: Is there a role for chemoprevention? PMID: 29375745 Ref: Associations between VDR gene polymorphisms and colorectal cancer susceptibility: an updated meta-analysis based on 39 case-control studies. PMID: 29560132 Ref: MEG3 Activated by Vitamin D Inhibits Colorectal Cancer Cells Proliferation and Migration via Regulating Clusterin. PMID: 29628342 Ref: The burgeoning role of cytochrome P450-mediated vitamin D metabolites against colorectal cancer. PMID: 29719203 Ref: Adipose tissue inflammation and VDR expression and methylation in colorectal cancer. PMID: 29719581 Ref: Mechanisms of action of vitamin D in colon cancer. PMID: 29981368 Ref: Vitamin D receptor FokI polymorphism and the risks of colorectal cancer, inflammatory bowel disease, and colorectal adenoma. PMID: 30150667 Ref: miR-372 and miR-373 enhance the stemness of colorectal cancer cells by repressing differentiation signaling pathways. PMID: 30171794 Ref: [Bone and calcium metabolism associated with malignancy. Vitamin D and cancer.] PMID: 30374002 |