Primary Site >> Pancreatic Cancer

Gene >> VAV1

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Ref: Cell growth and metastasis in pancreatic cancer: is Vav the Rho'd to activation?
PMID: 12622410
Ref: Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis.
PMID: 15652748
Ref: VAV1: a new target in pancreatic cancer?
PMID: 15970675
Ref: Flesh and blood: the story of Vav1, a gene that signals in hematopoietic cells but can be transforming in human malignancies.
PMID: 17590270
Ref: Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity.
PMID: 20457609
Ref: Dynamin 2 potentiates invasive migration of pancreatic tumor cells through stabilization of the Rac1 GEF Vav1.
PMID: 23537630
Ref: Vav1 as a central regulator of invadopodia assembly.
PMID: 24332539
Ref: Targeting Pancreatic Cancer Metastasis by Inhibition of Vav1, a Driver of Tumor Cell Invasion.
PMID: 25977335
Ref: TGFbeta promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1.
PMID: 27893715