Primary Site >> Colorectal Cancer

Gene >> VANGL1

  • 2005
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Ref: Suppression of progression and metastasis of established colon tumors in mice by intravenous delivery of short interfering RNA targeting KITENIN, a metastasis-enhancing protein.
PMID: 16204073
 Ref: Vangl1 protein acts as a downstream effector of intestinal trefoil factor (ITF)/TFF3 signaling and regulates wound healing of intestinal epithelium.
PMID: 16410243
Ref: Expression of KITENIN, a KAI1/CD82 binding protein and metastasis enhancer, in bladder cancer cell lines: relationship to KAI1/CD82 levels and invasive behaviour.
PMID: 17089048
 Ref: KITENIN recruits Dishevelled/PKC delta to form a functional complex and controls the migration and invasiveness of colorectal cancer cells.
PMID: 18653728
 Ref: MicroRNA-145 targets YES and STAT1 in colon cancer cells.
PMID: 20098684
Ref: Intratumoral administration of anti-KITENIN shRNA-loaded PEI-alt-PEG nanoparticles suppressed colon carcinoma established subcutaneously in mice.
PMID: 20358939
 Ref: Expression of KITENIN in human colorectal cancer and its relation to tumor behavior and progression.
PMID: 21418393
Ref: Gene therapy for head and neck squamous cell carcinoma using KITENIN (KAI1 COOH-Terminal Interacting Tetraspanin)-antisense therapy.
PMID: 21488189
Ref: Intravenous KITENIN shRNA injection suppresses hepatic metastasis and recurrence of colon cancer in an orthotopic mouse model.
PMID: 22065899
 Ref: An unconventional KITENIN/ErbB4-mediated downstream signal of EGF upregulates c-Jun and the invasiveness of colorectal cancer cells.
PMID: 24893630
Ref: KITENIN-targeting microRNA-124 suppresses colorectal cancer cell motility and tumorigenesis.
PMID: 24909917
 Ref: Elevated Coexpression of KITENIN and the ErbB4 CYT-2 Isoform Promotes the Transition from Colon Adenoma to Carcinoma Following APC loss.
PMID: 26527747
Ref: Aberrant DNA methylation of WNT pathway genes in the development and progression of CIMP-negative colorectal cancer.
PMID: 27245242
 Ref: KITENIN functions as a fine regulator of ErbB4 expression level in colorectal cancer via protection of ErbB4 from E3-ligase Nrdp1-mediated degradation.
PMID: 27648936