Primary Site >> Colorectal Cancer
Gene >> USP22
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Ref: Increased expression of ubiquitin-specific protease 22 can promote cancer progression and predict therapy failure in human colorectal cancer. PMID: 21039844 |
Ref: Aberrant expression of USP22 is associated with liver metastasis and poor prognosis of colorectal cancer. PMID: 21337558 |
Ref: Knock-down of ubiquitin-specific protease 22 by micro-RNA interference inhibits colorectal cancer growth. PMID: 21773699 Ref: USP22 acts as an oncogene by the activation of BMI-1-mediated INK4a/ARF pathway and Akt pathway. PMID: 21928107 Ref: Expression patterns of USP22 and potential targets BMI-1, PTEN, p-AKT in non-small-cell lung cancer. PMID: 22717106 |
Ref: Ubiquitin-specific peptidase USP22 negatively regulates the STAT signaling pathway by deubiquitinating SIRT1. PMID: 24969755 |
Ref: Ubiquitin-specific peptidase 22 inhibits colon cancer cell invasion by suppressing the signal transducer and activator of transcription 3/matrix metalloproteinase 9 pathway. PMID: 25902005 Ref: Decreased H2B monoubiquitination and overexpression of ubiquitin-specific protease enzyme 22 in malignant colon carcinoma. PMID: 25971547 Ref: Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1. PMID: 27030811 |
Ref: USP22 drives colorectal cancer invasion and metastasis via epithelial-mesenchymal transition by activating AP4. PMID: 28427243 |
Ref: Ubiquitin-Specific Peptidase 22 Contributes to Colorectal Cancer Stemness and Chemoresistance via Wnt/beta-Catenin Pathway. PMID: 29689565 Ref: Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells. PMID: 30224477 Ref: MiR-30-5p suppresses cell chemoresistance and stemness in colorectal cancer through USP22/Wnt/beta-catenin signaling axis. PMID: 30338942 |