Primary Site >> Colorectal Cancer

Gene >> UPP1

  • 1998
  • 2002
  • 2011
  • 2013
  • 2017
  • 2018
Ref: Expression, characterization, and detection of human uridine phosphorylase and identification of variant uridine phosphorolytic activity in selected human tumors.
PMID: 9850074
Ref: Uridine phosphorylase (-/-) murine embryonic stem cells clarify the key role of this enzyme in the regulation of the pyrimidine salvage pathway and in the activation of fluoropyrimidines.
PMID: 11956089
Ref: Differential expression of uridine phosphorylase in tumors contributes to an improved fluoropyrimidine therapeutic activity.
PMID: 21954436
Ref: Design of novel potent inhibitors of human uridine phosphorylase-1: synthesis, inhibition studies, thermodynamics, and in vitro influence on 5-fluorouracil cytotoxicity.
PMID: 24131420
Ref: Colonic transcriptional response to 1alpha,25(OH)2 vitamin D3 in African- and European-Americans.
PMID: 28163244
Ref:
PMID: 28510243
Ref: Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer.
PMID: 29382334
Ref: Vitamin D Regulation of the Uridine Phosphorylase 1 Gene and Uridine-Induced DNA Damage in Colon in African Americans and European Americans.
PMID: 29964038