Primary Site >> Colorectal Cancer

Gene >> UNG

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Ref: Analysis of uracil DNA glycosylase in human colorectal cancer.
PMID: 11172609
Ref: The role of dUTPase and uracil-DNA repair in cancer chemotherapy.
PMID: 12374095
Ref: Novel aspects of macromolecular repair and relationship to human disease.
PMID: 14985856
Ref: Variance in the expression of 5-Fluorouracil pathway genes in colorectal cancer.
PMID: 15814641
Ref: Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition.
PMID: 17029639
Ref: A human cancer-associated truncation of MBD4 causes dominant negative impairment of DNA repair in colon cancer cells.
PMID: 17285135
Ref: 5-Fluorouracil is efficiently removed from DNA by the base excision and mismatch repair systems.
PMID: 18054558
Ref: Ugene, a newly identified protein that is commonly overexpressed in cancer and binds uracil DNA glycosylase.
PMID: 18676834
Ref: Aging alters folate homeostasis and DNA damage response in colon.
PMID: 22306610
Ref: Unique mutational profile associated with a loss of TDG expression in the rectal cancer of a patient with a constitutional PMS2 deficiency.
PMID: 22608206
Ref: Transcriptional regulation of thymine DNA glycosylase (TDG) by the tumor suppressor protein p53.
PMID: 23165212
Ref: Uracil-DNA glycosylase expression determines human lung cancer cell sensitivity to pemetrexed.
PMID: 23873851
Ref: Extreme assay sensitivity in molecular diagnostics further unveils intratumour heterogeneity in metastatic colorectal cancer as well as artifactual low-frequency mutations in the KRAS gene.
PMID: 28618430
Ref: Thiol-ene miniemulsion polymerization of a biobased monomer for biomedical applications.
PMID: 28843199
Ref: Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.
PMID: 29698444