Primary Site >> Colorectal Cancer

Gene >> UNC5A

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Ref: Cloning of three mouse Unc5 genes and their expression patterns at mid-gestation.
PMID: 12351186
Ref: The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment.
PMID: 12655055
Ref: Netrin-1 is a chemorepellent for oligodendrocyte precursor cells in the embryonic spinal cord.
PMID: 12736344
Ref: Surface expression of the netrin receptor UNC5H1 is regulated through a protein kinase C-interacting protein/protein kinase-dependent mechanism.
PMID: 14672991
Ref: Netrin-1 and its receptors in tumorigenesis.
PMID: 15573119
Ref: Protein interacting with C-kinase 1/protein kinase Calpha-mediated endocytosis converts netrin-1-mediated repulsion to attraction.
PMID: 16554470
Ref: Characterization of the receptors for axon guidance factor netrin-4 and identification of the binding domains.
PMID: 17174565
Ref: Netrin inhibits regenerative axon growth of adult dorsal root ganglion neurons in vitro.
PMID: 17728502
Ref: Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies.
PMID: 17967459
Ref: Netrins and their receptors.
PMID: 18269208
Ref: NF-kappaB regulates netrin-1 expression and affects the conditional tumor suppressive activity of the netrin-1 receptors.
PMID: 18692059
Ref: Netrin-4 enhances angiogenesis and neurologic outcome after cerebral ischemia.
PMID: 18985053
Ref: Netrin-1 increases proliferation and migration of renal proximal tubular epithelial cells via the UNC5B receptor.
PMID: 19211685
Ref: The netrin protein family.
PMID: 19785719
Ref: The ratio of 'deleted in colorectal cancer' to 'uncoordinated-5A' netrin-1 receptors on the growth cone regulates mossy fibre directionality.
PMID: 19858080
Ref: Identification of UNC5A as a novel transcriptional target of tumor suppressor p53 and a regulator of apoptosis.
PMID: 20372800
Ref: Netrin-1 regulates Th1/Th2/Th17 cytokine production and inflammation through UNC5B receptor and protects kidney against ischemia-reperfusion injury.
PMID: 20693423
Ref: Netrin-1 simultaneously suppresses corneal inflammation and neovascularization.
PMID: 22323486
Ref: Prenatal activation of maternal TLR3 receptors by viral-mimetic poly(I:C) modifies GluN2B expression in embryos and sonic hedgehog in offspring in the absence of kynurenine pathway activation.
PMID: 23981041
Ref: The crystal structure of netrin-1 in complex with DCC reveals the bifunctionality of netrin-1 as a guidance cue.
PMID: 25123307
Ref: Netrin-1-Regulated Distribution of UNC5B and DCC in Live Cells Revealed by TICCS.
PMID: 26840727