Primary Site >> Colorectal Cancer

Gene >> UHRF1

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Ref: Intake of grape-derived polyphenols reduces C26 tumor growth by inhibiting angiogenesis and inducing apoptosis.
PMID: 20442318
Ref: DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination.
PMID: 21045206
Ref: NIRF is frequently upregulated in colorectal cancer and its oncogenicity can be suppressed by let-7a microRNA.
PMID: 22018986
Ref: UHRF1 promotes cell growth and metastasis through repression of p16(ink(4)a) in colorectal cancer.
PMID: 22219067
Ref: UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and mediates colorectal cancer progression.
PMID: 22286757
Ref: UHRF1 expression is upregulated and associated with cellular proliferation in colorectal cancer.
PMID: 23023523
Ref: Green tea polyphenol epigallocatechin 3-gallate, contributes to the degradation of DNMT3A and HDAC3 in HCT 116 human colon cancer cells.
PMID: 24324066
Ref: Luteolin induces apoptosis in BE colorectal cancer cells by downregulating calpain, UHRF1, and DNMT1 expressions.
PMID: 25207720
Ref: Regulation of UHRF1 by microRNA-9 modulates colorectal cancer cell proliferation and apoptosis.
PMID: 25940709
Ref: Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1.
PMID: 26768845
Ref: Hinokitiol induces DNA demethylation via DNMT1 and UHRF1 inhibition in colon cancer cells.
PMID: 28241740
Ref: Targeting the SET and RING-associated (SRA) domain of ubiquitin-like, PHD and ring finger-containing 1 (UHRF1) for anti-cancer drug development.
PMID: 29899856