Primary Site >> Pancreatic Cancer

Gene >> UGT1A1

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Ref: UDP glucuronosyltransferase (UGT1A7) gene polymorphisms increase the risk of chronic pancreatitis and pancreatic cancer.
PMID: 12806614
Ref: Lack of association between UGT1A7, UGT1A9, ARP, SPINK1 and CFTR gene polymorphisms and pancreatic cancer in Italian patients.
PMID: 17072959
Ref: Pharmacogenetics in pancreatic cancer. Highlights from the 45th ASCO annual meeting. Orlando, FL, USA. May 29-June 2, 2009.
PMID: 19581734
Ref: Networking of differentially expressed genes in human cancer cells resistant to methotrexate.
PMID: 19732436
Ref: The maximum tolerated dose and biologic effects of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) in combination with irinotecan for patients with refractory solid tumors.
PMID: 20127092
Ref: Uridine diphosphate glucuronosyl transferase 1 family polypeptide A1 gene (UGT1A1) polymorphisms are associated with toxicity and efficacy in irinotecan monotherapy for refractory pancreatic cancer.
PMID: 23053265
Ref: Pharmacogenetics in pancreatic cancer.
PMID: 25076337
Ref: Increased UGT1A3 and UGT1A7 expression is associated with pancreatic cancer.
PMID: 25743847
Ref: Efficacy of Prophylactic G-CSF in Patients Receiving FOLFIRINOX: A Preliminary Retrospective Study.
PMID: 26631878
Ref: [A Case of Unresectable Advanced Rectal Cancer with a Pancreatic Tumor That Was Successfully Treated with FOLFIRINOX].
PMID: 28133357
Ref: Update on the role of nanoliposomal irinotecan in the treatment of metastatic pancreatic cancer.
PMID: 28804517
Ref: Terminating the criminal collaboration in pancreatic cancer: Nanoparticle-based synergistic therapy for overcoming fibroblast-induced drug resistance.
PMID: 28837958
Ref: Pharmacokinetic and pharmacogenetic markers of irinotecan toxicity.
PMID: 29932028