Primary Site >> Esophagus Cancer

Gene >> UGT1A1

  • 2010
  • 2012
  • 2013
Ref: Phase I study of NK012, a novel SN-38-incorporating micellar nanoparticle, in adult patients with solid tumors.
PMID: 20943763
 Ref: High enzyme activity UGT1A1 or low activity UGT1A8 and UGT2B4 genotypes increase esophageal cancer risk.
PMID: 22367021
 Ref: Associations between UGT1A1*6/*28 polymorphisms and irinotecan-induced severe toxicity in Chinese gastric or esophageal cancer patients.
PMID: 23783485