Primary Site >> Colorectal Cancer

Gene >> UBE2M

  • 2014
  • 2015
  • 2017
Ref: The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis.
PMID: 24821572
 Ref: Polymorphisms in Genes Involved in EGFR Turnover Are Predictive for Cetuximab Efficacy in Colorectal Cancer.
PMID: 26206335
 Ref: Discovery of benzothiazole derivatives as novel non-sulfamide NEDD8 activating enzyme inhibitors by target-based virtual screening.
PMID: 28388520