Primary Site >> Colorectal Cancer
Gene >> TYR
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Ref: Tyrosinase activity in the sera of patients with malignant melanoma: method and specificity. PMID: 411760 |
Ref: Proteins phosphorylated on tyrosine as markers of human tumor cell lines. PMID: 2435663 |
Ref: Effects of epidermal growth factor and analogues of luteinizing hormone-releasing hormone and somatostatin on phosphorylation and dephosphorylation of tyrosine residues of specific protein substrates in various tumors. PMID: 1672042 Ref: Altered protein tyrosine kinase levels in human colon carcinoma. PMID: 1985753 |
Ref: Absence of tRNA-guanine transglycosylase in a human colon adenocarcinoma cell line. PMID: 1378304 Ref: Purification and characterization of an enterotoxin from Bacteroides fragilis. PMID: 1548060 |
Ref: c-Yes tyrosine kinase activity in human colon carcinoma. PMID: 7690925 Ref: Genetic variation in thymidylate synthase confers resistance to 5-fluorodeoxyuridine. PMID: 8178730 |
Ref: Regulation of the Src tyrosine kinase and Syp tyrosine phosphatase by their cellular association. PMID: 7478513 Ref: Src activity increases and Yes activity decreases during mitosis of human colon carcinoma cells. PMID: 7739521 Ref: Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha. PMID: 7797556 |
Ref: Progression of familial adenomatous polyposis (FAP) colonic cells after transfer of the src or polyoma middle T oncogenes: cooperation between src and HGF/Met in invasion. PMID: 9010033 Ref: Adhesion of HT-29 colon carcinoma cells to E-selectin results in increased tyrosine phosphorylation and decreased activity of c-src. PMID: 9178821 Ref: [Activity of cathepsin D in some neoplasms of the gastrointestinal tract]. PMID: 9377676 |
Ref: Functional genetic tests of DNA mismatch repair protein activity in Saccharomyces cerevisiae. PMID: 9630599 Ref: Enhanced ligand-induced activation of EGF-receptor and overall tyrosine kinase and phospholipase C in colonocytes isolated from azoxymethane-treated rats. PMID: 9684124 Ref: Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility. PMID: 10026993 Ref: Four new mutations in the DNA mismatch repair gene MLH1 in colorectal cancers with microsatellite instability. Mutations in brief no. 157. Online. PMID: 10627141 |
Ref: Activating SRC mutation in a subset of advanced human colon cancers. PMID: 9988270 Ref: Augmentation of melanoma-specific gene expression using a tandem melanocyte-specific enhancer results in increased cytotoxicity of the purine nucleoside phosphorylase gene in melanoma. PMID: 10223723 Ref: Interaction between haemochromatosis and transferrin receptor genes in different neoplastic disorders. PMID: 10383894 Ref: Pre-clinical evaluation of [(111)In-DTPA-Pro(1), Tyr(4)]bombesin, a new radioligand for bombesin-receptor scintigraphy. PMID: 10521803 Ref: cis-Determinants in the cytoplasmic domain of CEACAM1 responsible for its tumor inhibitory function. PMID: 10523833 Ref: Expression of genes for microphthalmia isoforms, Pax3 and MSG1, in human melanomas. PMID: 10644012 Ref: Role of the cytoskeleton in adhesion stabilization of human colorectal carcinoma cells to extracellular matrix components under dynamic conditions of laminar flow. PMID: 10919716 |
Ref: Mutation of the SRC gene in endometrial carcinoma. PMID: 10804287 Ref: Increased expression of the mRNA encoding the somatostatin receptor subtype five in human colorectal adenocarcinoma. PMID: 10828833 Ref: Characterization of gastrin-releasing peptide and its receptor aberrantly expressed by human colon cancer cell lines. PMID: 10953054 Ref: Time-dependent dephosphorylation through serine/threonine phosphatases is required for stable adhesion of highly and poorly metastatic HT-29 colon carcinoma cell lines to collagen. PMID: 10953284 Ref: Development of plasmin and plasma kallikrein selective inhibitors and their effect on M1 (melanoma) and HT29 cell lines. PMID: 11012033 Ref: Interaction between haemochromatosis and transferrin receptor genes in hepatocellular carcinoma. PMID: 11096344 Ref: Expression of melanoma inhibitory activity in melanoma and nonmelanoma tissue specimens. PMID: 11112213 Ref: Failure of detection of the tyrosine to histidine substitution at the residue 33 of thymidylate synthase in human colorectal cancer. A preliminary study. PMID: 11205269 |
Ref: Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug. PMID: 11329255 Ref: Reverse transcriptase-polymerase chain reaction (RT-PCR) analysis of nonsentinel nodes following completion lymphadenectomy for melanoma. PMID: 11368537 Ref: In vivo evaluation of an 111In-labeled ST-peptide analog for specific-targeting of human colon cancers. PMID: 11711309 |
Ref: Comparison of the RNA-amplification based methods RT-PCR and NASBA for the detection of circulating tumour cells. PMID: 11857020 Ref: PTEN regulates tumor cell adhesion of colon carcinoma cells under dynamic conditions of fluid flow. PMID: 11857088 Ref: Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells. PMID: 12221076 |
Ref: Mutation analysis in the coding sequence of thymidine kinase 1 in breast and colorectal cancer. PMID: 12699056 Ref: Sodium salicylate induces apoptosis in HCT116 colorectal cancer cells through activation of p38MAPK. PMID: 12851702 |
Ref: High and low affinity receptors mediate growth effects of gastrin and gastrin-Gly on DLD-1 human colonic carcinoma cells. PMID: 14706850 Ref: Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells. PMID: 14715079 Ref: Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C. PMID: 15073169 Ref: In vitro and in vivo comparison of human Escherichia coli heat-stable peptide analogues incorporating the 111In-DOTA group and distinct linker moieties. PMID: 15264876 |
Ref: Implication of STAT3 signaling in human colonic cancer cells during intestinal trefoil factor 3 (TFF3) -- and vascular endothelial growth factor-mediated cellular invasion and tumor growth. PMID: 15665295 Ref: Microsomal epoxide hydrolase polymorphisms and risk for advanced colorectal adenoma. PMID: 15668489 Ref: Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior. PMID: 15735019 Ref: [Mutation detection of mismatch repair genes in hereditary nonpolyposis colorectal cancer by denaturing high-performance liquid chromatography]. PMID: 15842942 Ref: Transient upregulation of GRP and its receptor critically regulate colon cancer cell motility during remodeling. PMID: 15890713 Ref: [Effect of gastrin on invasiveness of human colon cancer cells]. PMID: 15949418 Ref: SKI-606, a Src/Abl inhibitor with in vivo activity in colon tumor xenograft models. PMID: 15958584 Ref: Furanoid sugar amino acids as dipeptide mimics in design of analogs of vasoactive intestinal peptide receptor binding inhibitor. PMID: 16000121 Ref: Butyrate regulates the expression of c-Src and focal adhesion kinase and inhibits cell invasion of human colon cancer cells. PMID: 16001424 Ref: Insight into the roles of tyrosine 82 and glycine 253 in the Escherichia coli adenine glycosylase MutY. PMID: 16245934 |
Ref: A growth-suppressive function for the c-fes protein-tyrosine kinase in colorectal cancer. PMID: 16455651 Ref: Integrin alpha2-mediated ERK and calpain activation play a critical role in cell adhesion and motility via focal adhesion kinase signaling: identification of a novel signaling pathway. PMID: 16461767 Ref: Checkpoint kinase 1-mediated phosphorylation of Cdc25C and bad proteins are involved in antitumor effects of loratadine-induced G2/M phase cell-cycle arrest and apoptosis. PMID: 16649252 Ref: Tumor-cell-targeted methionine-enkephalin analogues containing unnatural amino acids: design, synthesis, and in vitro antitumor activity. PMID: 16722632 Ref: Vaccination with melanoma lysate-pulsed dendritic cells, of patients with advanced colorectal carcinoma: report from a phase I study. PMID: 16918131 Ref: Deoxycholic acid differentially regulates focal adhesion kinase phosphorylation: role of tyrosine phosphatase ShP2. PMID: 16920701 Ref: Investigation of anti-tumor mechanisms of K2154: characterization of tubulin isotypes, mitotic arrest and apoptotic machinery. PMID: 17102938 Ref: Identification of potential biomarkers for measuring inhibition of Src kinase activity in colon cancer cells following treatment with dasatinib. PMID: 17148760 |
Ref: PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition. PMID: 17409395 Ref: Eps8 facilitates cellular growth and motility of colon cancer cells by increasing the expression and activity of focal adhesion kinase. PMID: 17496330 Ref: Antiapoptotic effects of progastrin on pancreatic cancer cells are mediated by sustained activation of nuclear factor-{kappa}B. PMID: 17671195 Ref: Development of albumin-binding camptothecin prodrugs using a Peptide positional scanning library. PMID: 17915955 Ref: Protein kinase C delta is phosphorylated on five novel Ser/Thr sites following inducible overexpression in human colorectal cancer cells. PMID: 17965192 Ref: Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas. PMID: 18093316 |
Ref: Cathepsin D and carcino-embryonic antigen in serum, urine and tissues of colon adenocarcinoma patients. PMID: 18613372 Ref: Antiproliferative effect of sulindac in colonic neoplasia prevention: role of COOH-terminal Src kinase. PMID: 18644992 |
Ref: Macrophage-derived interleukin-6 up-regulates MUC1, but down-regulates MUC2 expression in the human colon cancer HT-29 cell line. PMID: 19201396 |
Ref: Restoration of absent in melanoma 2 (AIM2) induces G2/M cell cycle arrest and promotes invasion of colorectal cancer cells. PMID: 19795419 Ref: Prognostic effect of activated EGFR expression in human colon carcinomas: comparison with EGFR status. PMID: 19997103 Ref: Affinity of synthetic peptide fragments of MyoD for Id1 protein and their biological effects in several cancer cells. PMID: 20235117 Ref: Neutralization of interleukin (IL)-10 released by monocytes/macrophages enhances the up-regulatory effect of monocyte/macrophage-derived IL-6 on expressions of IL-6 and MUC1, and migration in HT-29 colon cancer cells. PMID: 20851386 Ref: Inhibitory effect of somatostatin Peptide analogues on DNA polymerase activity and human cancer cell proliferation. PMID: 21187461 |
Ref: The death receptor CD95 activates the cofilin pathway to stimulate tumour cell invasion. PMID: 21760611 Ref: Cellular settings mediating Src Substrate switching between focal adhesion kinase tyrosine 861 and CUB-domain-containing protein 1 (CDCP1) tyrosine 734. PMID: 21994943 Ref: [A case of amelanotic anorectal malignant melanoma mimicking gastrointestinal stromal tumor]. PMID: 22189238 |
Ref: Roles of STAT3 and ZEB1 proteins in E-cadherin down-regulation and human colorectal cancer epithelial-mesenchymal transition. PMID: 22205702 Ref: New lyophilized kit for rapid radiofluorination of peptides. PMID: 22273147 Ref: Src tyrosine kinase phosphorylation of nuclear receptor HNF4alpha correlates with isoform-specific loss of HNF4alpha in human colon cancer. PMID: 22308320 Ref: Structural stability of human protein tyrosine phosphatase rho catalytic domain: effect of point mutations. PMID: 22389709 Ref: Anti-melanogenic property of geoditin A in murine B16 melanoma cells. PMID: 22412813 Ref: A novel angiogenesis inhibitor impairs lovo cell survival via targeting against human VEGFR and its signaling pathway of phosphorylation. PMID: 23059825 |
Ref: Tyrosine phosphorylation of the Rho guanine nucleotide exchange factor Trio regulates netrin-1/DCC-mediated cortical axon outgrowth. PMID: 23230270 Ref: Inhibitory effect of novel somatostatin peptide analogues on human cancer cell growth based on the selective inhibition of DNA polymerase beta. PMID: 23266186 Ref: Sepiapterin ameliorates chemically induced murine colitis and azoxymethane-induced colon cancer. PMID: 23912334 Ref: Improvement of pharmacokinetic and antitumor activity of PEGylated liposomal doxorubicin by targeting with N-methylated cyclic RGD peptide in mice bearing C-26 colon carcinomas. PMID: 24148663 |
Ref: In vitro studies on the cytotoxicity, and elastase and tyrosinase inhibitory activities of marigold (Tagetes erecta L.) flower extracts. PMID: 24348799 Ref: Ruthenium-nitrosyl complexes with glycine, L-alanine, L-valine, L-proline, D-proline, L-serine, L-threonine, and L-tyrosine: synthesis, X-ray diffraction structures, spectroscopic and electrochemical properties, and antiproliferative activity. PMID: 24555845 Ref: Membrane androgen receptor down-regulates c-src-activity and beta-catenin transcription and triggers GSK-3beta-phosphorylation in colon tumor cells. PMID: 25301365 |
Ref: Promotion of colorectal cancer invasion and metastasis through activation of NOTCH-DAB1-ABL-RHOGEF protein TRIO. PMID: 25432929 Ref: Human enhancer of filamentation 1-induced colorectal cancer cell migration: Role of serine phosphorylation and interaction with the breast cancer anti-estrogen resistance 3 protein. PMID: 25817040 Ref: Gastrin-stimulated Galpha13 Activation of Rgnef Protein (ArhGEF28) in DLD-1 Colon Carcinoma Cells. PMID: 25922072 Ref: The relevance of cell type- and tumor zone-specific VEGFR-2 activation in locally advanced colon cancer. PMID: 25967108 Ref: The Mutant KRAS Gene Up-regulates BCL-XL Protein via STAT3 to Confer Apoptosis Resistance That Is Reversed by BIM Protein Induction and BCL-XL Antagonism. PMID: 26245900 Ref: Dynamic monitoring of plasma amino acids and carnitine during chemotherapy of patients with alimentary canal malignancies and its clinical value. PMID: 26300648 |
Ref: Antiproliferative activity of Humulus lupulus extracts on human hepatoma (Hep3B), colon (HT-29) cancer cells and proteases, tyrosinase, beta-lactamase enzyme inhibition studies. PMID: 25683080 Ref: STAT3-dependent TXNDC17 expression mediates Taxol resistance through inducing autophagy in human colorectal cancer cells. PMID: 26976343 Ref: Blockage of Autophagy Rescues the Dual PI3K/mTOR Inhibitor BEZ235-induced Growth Inhibition of Colorectal Cancer Cells. PMID: 27294206 |
Ref: Highly Increased 125I-JR11 Antagonist Binding In Vitro Reveals Novel Indications for sst2 Targeting in Human Cancers. PMID: 27561878 Ref: Rapid differentiating colorectal cancer and colorectal polyp using dried blood spot mass spectrometry metabolomic approach. PMID: 28322027 |
Ref: A novel in-cell ELISA method for screening of compounds inhibiting TRKA phosphorylation, using KM12cell line harboring TRKA rearrangement. PMID: 29360440 Ref: Synthesis, Cytotoxicity And Antioxidant Activity Of New Analogues Of Rc-121 Synthetic Derivatives Of Somatostatin. PMID: 29667555 Ref: NDRG3 facilitates colorectal cancer metastasis through activating Src phosphorylation. PMID: 29844682 Ref: Extracellular gamma-synuclein promotes tumor cell motility by activating beta1 integrin-focal adhesion kinase signaling pathway and increasing matrix metalloproteinase-24, -2 protein secretion. PMID: 29903032 Ref: Lycorine Displays Potent Antitumor Efficacy in Colon Carcinoma by Targeting STAT3. PMID: 30135654 Ref: Retinoic Acid Receptor alpha Knockdown Suppresses the Tumorigenicity of Esophageal Carcinoma via Wnt/beta-catenin Pathway. PMID: 30155836 |