Primary Site >> Esophagus Cancer

Gene >> TYMS

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Ref: [Inhibition of thymidylate synthetase and antiproliferative effect by 1-hexylcarbamoyl-5-fluorouracil].
PMID: 3190249
 Ref: Biopsy specimen microvessel density is a useful prognostic marker in patients with T(2-4)M(0) esophageal cancer treated with chemoradiotherapy.
PMID: 11801548
 Ref: A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA.
PMID: 15289858
 Ref: Downregulation of TS, DPD, ERCC1, GST-Pi, EGFR, and HER2 gene expression after neoadjuvant three-modality treatment in patients with esophageal cancer.
PMID: 15737843
 Ref: Genomic imbalances in esophageal carcinoma cell lines involve Wnt pathway genes.
PMID: 21734802
Ref: Thymidylate synthetase and dihydropyrimidine dehydrogenase mRNA levels in esophageal cancer.
PMID: 22866080
 Ref: Multidrug resistance in primary tumors and metastases in patients with esophageal squamous cell carcinoma.
PMID: 23508648
 Ref: Stem cell-like side populations in esophageal cancer: a source of chemotherapy resistance and metastases.
PMID: 24021093
Ref: Expression of ERCC1, TYMS, TUBB3, RRM1 and TOP2A in patients with esophageal squamous cell carcinoma: A hierarchical clustering analysis.
PMID: 24926347
Ref: MicroRNA signatures in chemotherapy resistant esophageal cancer cell lines.
PMID: 25356050
 Ref: A systematic review and meta-analysis of somatic and germline DNA sequence biomarkers of esophageal cancer survival, therapy response and stage.
PMID: 25214541
 Ref: Germline and somatic genetic predictors of pathological response in neoadjuvant settings of rectal and esophageal cancers: systematic review and meta-analysis.
PMID: 26122021
Ref: Competitive Binding Between Id1 and E2F1 to Cdc20 Regulates E2F1 Degradation and Thymidylate Synthase Expression to Promote Esophageal Cancer Chemoresistance.
PMID: 26475334
Ref: Tumor profiling of co-regulated receptor tyrosine kinase and chemoresistant genes reveal different targeting options for lung and gastroesophageal cancers.
PMID: 28078044