Primary Site >> Colorectal Cancer
Gene >> TXNRD1
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Ref: Thioredoxin reductase 1 expression in colon cancer: discrepancy between in vitro and in vivo findings. PMID: 13679440 |
Ref: Thioredoxin reductase is required for the inactivation of tumor suppressor p53 and for apoptosis induced by endogenous electrophiles. PMID: 16777982 Ref: Isothiocyanate iberin modulates phase II enzymes, posttranslational modification of histones and inhibits growth of Caco-2 cells by inducing apoptosis. PMID: 17167713 |
Ref: A cellular and molecular investigation of the action of PMX464, a putative thioredoxin inhibitor, in normal and colorectal cancer cell lines. PMID: 17572693 Ref: Thioredoxin-like domains required for glucose regulatory protein 58 mediated reductive activation of mitomycin C leading to DNA cross-linking. PMID: 17938265 |
Ref: Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. PMID: 18483336 |
Ref: Thioredoxin reductase 1 ablation sensitizes colon cancer cells to methylseleninate-mediated cytotoxicity. PMID: 19782697 |
Ref: JS-K, a nitric oxide prodrug, has enhanced cytotoxicity in colon cancer cells with knockdown of thioredoxin reductase 1. PMID: 20098717 Ref: Selenium-enriched milk proteins and selenium yeast affect selenoprotein activity and expression differently in mouse colon. PMID: 20346189 |
Ref: Expression of selenium-containing proteins in human colon carcinoma tissue. PMID: 21868509 Ref: Enhancement of the efficacy of mitomycin C-mediated apoptosis in human colon cancer cells with RNAi-based thioredoxin reductase 1 deficiency. PMID: 22977591 |
Ref: Genetic variation in selenoprotein genes, lifestyle, and risk of colon and rectal cancer. PMID: 22615972 |
Ref: Induction of complementary function reductase enzymes in colon cancer cells by dithiole-3-thione versus sodium selenite. PMID: 25179160 Ref: The 15kDa selenoprotein and thioredoxin reductase 1 promote colon cancer by different pathways. PMID: 25886253 Ref: Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors. PMID: 26155417 |
Ref: The anticancer effect related to disturbances in redox balance on Caco-2 cells caused by an alkynyl gold(I) complex. PMID: 27842247 Ref: Cystatin SN inhibits auranofin-induced cell death by autophagic induction and ROS regulation via glutathione reductase activity in colorectal cancer. PMID: 28300829 Ref: Targeted proteome analysis with isotope-coded protein labels for monitoring the influence of dietary phytochemicals on the expression of cytoprotective proteins in primary human colon cells. PMID: 28688915 |
Ref: Costunolide specifically binds and inhibits thioredoxin reductase 1 to induce apoptosis in colon cancer. PMID: 29037867 Ref: Identification of serum proteins AHSG, FGA and APOA-I as diagnostic biomarkers for gastric cancer. PMID: 29719494 |