Primary Site >> Liver Cancer
Gene >> TTK
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Ref: Identification of prognostic biomarkers in hepatitis B virus-related hepatocellular carcinoma and stratification by integrative multi-omics analysis. PMID: 24859455 Ref: Expression and function analysis of mitotic checkpoint genes identifies TTK as a potential therapeutic target for human hepatocellular carcinoma. PMID: 24905462 Ref: Viral expression and molecular profiling in liver tissue versus microdissected hepatocytes in hepatitis B virus-associated hepatocellular carcinoma. PMID: 25141867 |
Ref: Multifocal hepatocellular carcinoma: intrahepatic metastasis or multicentric carcinogenesis? PMID: 25705636 Ref: Decoding multifocal hepatocellular carcinoma: an opportune pursuit. PMID: 26151061 Ref: Wading through the noise of "multi-omics" to identify prognostic biomarkers in hepatocellular carcinoma. PMID: 26312246 Ref: TTK activates Akt and promotes proliferation and migration of hepatocellular carcinoma cells. PMID: 26418879 |
Ref: Utility of the dual-specificity protein kinase TTK as a therapeutic target for intrahepatic spread of liver cancer. PMID: 27618777 |
Ref: TC Mps1 12, a novel Mps1 inhibitor, suppresses the growth of hepatocellular carcinoma cells via the accumulation of chromosomal instability. PMID: 28299790 Ref: TTK Inhibitors as a Targeted Therapy for CTNNB1 (beta-catenin) Mutant Cancers. PMID: 28751540 Ref: Gene expression profiling, pathway analysis and subtype classification reveal molecular heterogeneity in hepatocellular carcinoma and suggest subtype specific therapeutic targets. PMID: 29025594 |
Ref: Insights into Resistance Mechanisms of Inhibitors to Mps1 C604Y Mutation via a Comprehensive Molecular Modeling Study. PMID: 29925769 |