Primary Site >> Pancreatic Cancer

Gene >> TSC2

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Ref: Localization of putative tumor suppressor loci by genome-wide allelotyping in human pancreatic endocrine tumors.
PMID: 9721882
Ref: Malignant pancreatic endocrine tumor in a child with tuberous sclerosis.
PMID: 14508401
Ref: Expression and prognostic value of tuberous sclerosis complex 2 gene product tuberin in human pancreatic cancer.
PMID: 16213898
Ref: New insights into the role of the tuberous sclerosis genes in leukemia.
PMID: 19286253
Ref: Well-differentiated pancreatic neuroendocrine carcinoma in tuberous sclerosis--case report and review of the literature.
PMID: 22173120
Ref: Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling.
PMID: 24466367
Ref: Metabolomic evaluation of Mitomycin C and rapamycin in a personalized treatment of pancreatic cancer.
PMID: 25505613
Ref: Whole-exome characterization of pancreatic neuroendocrine tumor cell lines BON-1 and QGP-1.
PMID: 25612765
Ref: Exome-level comparison of primary well-differentiated neuroendocrine tumors and their cell lines.
PMID: 26087898
Ref: BRSK2 induced by nutrient deprivation promotes Akt activity in pancreatic cancer via downregulation of mTOR activity.
PMID: 28591720
Ref: Assessment of pancreatic neuroendocrine tumor cytologic genotype diversity to guide personalized medicine using a custom gastroenteropancreatic next-generation sequencing panel.
PMID: 29212165
Ref: Expanding the Spectrum of Colonic Manifestations in Tuberous Sclerosis: L-Cell Neuroendocrine Tumor Arising in the Background of Rectal PEComa.
PMID: 28733877
Ref: Pancreatic neuroendocrine tumor in a patient with a TSC1 variant: case report and review of the literature.
PMID: 28887784
Ref: Hotspot DAXX, PTCH2 and CYFIP2 mutations in pancreatic neuroendocrine neoplasms.
PMID: 30021865