Primary Site >> Colorectal Cancer

Gene >> TRPV1

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Ref: Capsaicin, a spicy component of hot pepper, induces apoptosis by activation of the peroxisome proliferator-activated receptor gamma in HT-29 human colon cancer cells.
PMID: 15383218
Ref: Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P.
PMID: 16423891
Ref: Role of acylethanolamides in the gastrointestinal tract with special reference to food intake and energy balance.
PMID: 19285259
Ref: Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer.
PMID: 22231745
Ref: Vanilloid receptor-1 regulates neurogenic inflammation in colon and protects mice from colon cancer.
PMID: 22396497
Ref: Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors.
PMID: 22922338
Ref: Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid.
PMID: 25269802
Ref: Extravirgin olive oil up-regulates CB(1) tumor suppressor gene in human colon cancer cells and in rat colon via epigenetic mechanisms.
PMID: 25533906
Ref: Calcium-related neurotoxicity of oxaliplatin: understanding the mechanisms to drive therapy.
PMID: 26423088
Ref: Netrin-1 Contributes to Myelinated Afferent Fiber Sprouting and Neuropathic Pain.
PMID: 26482371
Ref: The gastrointestinal tract - a central organ of cannabinoid signaling in health and disease.
PMID: 27561826
Ref: Fatty acid amide hydrolase (FAAH) inhibitor PF-3845 reduces viability, migration and invasiveness of human colon adenocarcinoma Colo-205 cell line: an in vitro study.
PMID: 28850633
Ref: Determining the Crystal Structure of TRPV6
PMID: 30299652