Primary Site >> Colorectal Cancer
Gene >> TRPM8
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Ref: L type Ca(2)+ channel blockers prevent oxaliplatin-induced cold hyperalgesia and TRPM8 overexpression in rats. PMID: 22292988 Ref: Oxaliplatin-induced neurotoxicity involves TRPM8 in the mechanism of acute hypersensitivity to cold sensation. PMID: 22574275 |
Ref: Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid. PMID: 25269802 |
Ref: Calcium-related neurotoxicity of oxaliplatin: understanding the mechanisms to drive therapy. PMID: 26423088 |
Ref: TRPM8: a potential target for cancer treatment. PMID: 26803314 |