Primary Site >> Colorectal Cancer
Gene >> TRAP1
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Ref: TRAP1, a novel mitochondrial chaperone responsible for multi-drug resistance and protection from apoptotis in human colorectal carcinoma cells. PMID: 19217207 |
Ref: Mitochondrial chaperone Trap1 and the calcium binding protein Sorcin interact and protect cells against apoptosis induced by antiblastic agents. PMID: 20647321 |
Ref: Investigating neoplastic progression of ulcerative colitis with label-free comparative proteomics. PMID: 20828217 |
Ref: TRAP1 and the proteasome regulatory particle TBP7/Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins. PMID: 21979464 Ref: Correlation between mitochondrial TRAP-1 expression and lymph node metastasis in colorectal cancer. PMID: 23139614 |
Ref: Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1. PMID: 24113185 |
Ref: Combination of TRAP1 and ERCC1 Expression Predicts Clinical Outcomes in Metastatic Colorectal Cancer Treated with Oxaliplatin/5-Fluorouracil. PMID: 24520224 Ref: TRAP1-dependent regulation of p70S6K is involved in the attenuation of protein synthesis and cell migration: relevance in human colorectal tumors. PMID: 24962791 Ref: TRAP1 is involved in BRAF regulation and downstream attenuation of ERK phosphorylation and cell-cycle progression: a novel target for BRAF-mutated colorectal tumors. PMID: 25239454 Ref: Up-regulation of mitochondrial chaperone TRAP1 in ulcerative colitis associated colorectal cancer. PMID: 25493016 |
Ref: TRAP1 controls cell migration of cancer cells in metabolic stress conditions: Correlations with AKT/p70S6K pathways. PMID: 26071104 Ref: Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma. PMID: 26084290 |
Ref: TRAP1 regulates stemness through Wnt/beta-catenin pathway in human colorectal carcinoma. PMID: 27662365 |
Ref: Casticin induced apoptotic cell death and altered associated gene expression in human colon cancer colo 205 cells. PMID: 27862857 Ref: Clinicopathologic significance of TRAP1 expression in colorectal cancer: a large scale study of human colorectal adenocarcinoma tissues. PMID: 28088229 Ref: TRAP1 protein signature predicts outcome in human metastatic colorectal carcinoma. PMID: 28177905 |
Ref: Overexpression of the mitochondrial chaperone tumor necrosis factor receptor-associated protein 1 is associated with the poor prognosis of patients with colorectal cancer. PMID: 29552185 Ref: New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting. PMID: 29807796 |