Primary Site >> Stomach Cancer

Gene >> TRAF2

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Ref: H. pylori activates NF-kappaB through a signaling pathway involving IkappaB kinases, NF-kappaB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells.
PMID: 10889159
Ref: AP1- and NF-kappaB-binding sites conserved among mammalian WNT10B orthologs elucidate the TNFalpha-WNT10B signaling loop implicated in carcinogenesis and adipogenesis.
PMID: 17334647
Ref: Systems biology approach to identification of biomarkers for metastatic progression in gastric cancer.
PMID: 19649653
Ref: The essential role of TNIK gene amplification in gastric cancer growth.
PMID: 24566388
Ref: The ubiquitin ligase CHIP inactivates NF-kappaB signaling and impairs the ability of migration and invasion in gastric cancer cells.
PMID: 25672477
Ref: Methylation status of TRAF2 is associated with the diagnosis and prognosis of gastric cancer.
PMID: 26823737
Ref: DR5-Cbl-b/c-Cbl-TRAF2 complex inhibits TRAIL-induced apoptosis by promoting TRAF2-mediated polyubiquitination of caspase-8 in gastric cancer cells.
PMID: 28972304
Ref: High expression of tumor necrosis factor receptor-associated factor 2 promotes tumor metastasis and is associated with unfavorable prognosis in gastric cancer.
PMID: 28482378