Primary Site >> Liver Cancer
Gene >> TP73
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Ref: Two new p73 splice variants, gamma and delta, with different transcriptional activity. PMID: 9802988 |
Ref: Expression of p73, a novel protein related to the p53 tumour suppressor p53, and apoptosis in cholangiocellular carcinoma of the liver. PMID: 10362118 Ref: Expression of p73 and its relation to histopathology and prognosis in hepatocellular carcinoma. PMID: 10393724 Ref: Absence of mutation of the p73 gene localized at chromosome 1p36.3 in hepatocellular carcinoma. PMID: 10408709 Ref: HBV transcription repression in response to genotoxic stress is p53-dependent and abrogated by pX. PMID: 10602509 |
Ref: p73 is up-regulated in a subset of hepatocellular carcinomas. PMID: 10706549 Ref: Mutation analysis of P73 and TP53 in Merkel cell carcinoma. PMID: 10732753 Ref: Genetic alternations of p73 are infrequent but may occur in early stage hepatocellular carcinoma. PMID: 10928060 |
Ref: Correlation between p21(waf1) and p16(INK4a) expression in hepatocellular carcinoma. PMID: 11282486 Ref: Acquired expression of transcriptionally active p73 in hepatocellular carcinoma cells. PMID: 11526499 Ref: Comprehensive allelotyping of human intrahepatic cholangiocarcinoma. PMID: 11555575 |
Ref: p73 overexpression and nuclear accumulation in hepatitis C virus-associated hepatocellular carcinoma. PMID: 11991598 Ref: The prognostic molecular markers in hepatocellular carcinoma. PMID: 12046056 Ref: Overexpression but lack of mutation and methylation of p73 in hepatocellular carcinoma. PMID: 12546528 |
Ref: Deleted in liver cancer (DLC) 2 encodes a RhoGAP protein with growth suppressor function and is underexpressed in hepatocellular carcinoma. PMID: 12531887 Ref: [Determination of expression of eight p53-related genes in hepatocellular carcinoma with tissue microarrays]. PMID: 12866955 Ref: Aberrant promoter methylation profiles of tumor suppressor genes in hepatocellular carcinoma. PMID: 12937151 Ref: Methylation profiling of twenty four genes and the concordant methylation behaviours of nineteen genes that may contribute to hepatocellular carcinogenesis. PMID: 14672555 |
Ref: Clinical value of alterations in p73 gene, related to p53 at 1p36, in human hepatocellular carcinoma. PMID: 14719122 Ref: Quantitative TP73 transcript analysis in hepatocellular carcinomas. PMID: 14760085 |
Ref: Discrete breakpoint mapping and shortest region of overlap of chromosome arm 1q gain and 1p loss in human hepatocellular carcinoma detected by semiquantitative microsatellite analysis. PMID: 15495198 Ref: TAp63gamma can substitute for p53 in inducing expression of the maspin tumor suppressor. PMID: 15578720 Ref: TAp73/Delta Np73 influences apoptotic response, chemosensitivity and prognosis in hepatocellular carcinoma. PMID: 16195739 Ref: Family members p53 and p73 act together in chromatin modification and direct repression of alpha-fetoprotein transcription. PMID: 16203738 Ref: [Hypermethylation of Ras association domain family protein 1A, hypermethylated in cancer 1 and p73 genes in hepatocellular carcinoma]. PMID: 16412291 |
Ref: [Correlations of CpG island methylator phenotype and OPCML gene methylation to carcinogenesis of hepatocellular carcinoma]. PMID: 16764763 |
Ref: Autonomous growth and hepatocarcinogenesis in transgenic mice expressing the p53 family inhibitor DNp73. PMID: 17984115 Ref: Molecular mechanism of p73-mediated regulation of hepatitis B virus core promoter/enhancer II: implications for hepatocarcinogenesis. PMID: 18342333 |
Ref: Amphiregulin induces the alternative splicing of p73 into its oncogenic isoform DeltaEx2p73 in human hepatocellular tumors. PMID: 19664633 Ref: Plk1 regulates liver tumor cell death by phosphorylation of TAp63. PMID: 19668228 |
Ref: Chemotherapy-induced apoptosis in hepatocellular carcinoma involves the p53 family and is mediated via the extrinsic and the intrinsic pathway. PMID: 19711344 Ref: CpG island methylator phenotype associated with tumor recurrence in tumor-node-metastasis stage I hepatocellular carcinoma. PMID: 20112070 Ref: Nutlin-3 cooperates with doxorubicin to induce apoptosis of human hepatocellular carcinoma cells through p53 or p73 signaling pathways. PMID: 20174822 Ref: Interference with the p53 family network contributes to the gain of oncogenic function of mutant p53 in hepatocellular carcinoma. PMID: 20233581 Ref: MicroRNA-602 regulating tumor suppressive gene RASSF1A is overexpressed in hepatitis B virus-infected liver and hepatocellular carcinoma. PMID: 20364114 Ref: DeltaNp73beta is oncogenic in hepatocellular carcinoma by blocking apoptosis signaling via death receptors and mitochondria. PMID: 20581467 Ref: Prognostic significance of co-expression of nm23 and p57 protein in hepatocellular carcinoma. PMID: 20880063 |
Ref: MDM2 antagonist can inhibit tumor growth in hepatocellular carcinoma with different types of p53 in vitro. PMID: 21261729 Ref: p53-paralog DNp73 oncogene is repressed by IFNalpha/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor. PMID: 21399658 Ref: Dissection of cell context-dependent interactions between HBx and p53 family members in regulation of apoptosis: a role for HBV-induced HCC. PMID: 22030623 |
Ref: Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis. PMID: 22962577 |
Ref: Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of hepatocellular carcinoma in a Chinese population. PMID: 23065572 Ref: The sodium/iodide symporter NIS is a transcriptional target of the p53-family members in liver cancer cells. PMID: 24052075 |
Ref: A systemic approach to cancer treatment: tumor cell reprogramming focused on endocrine-related cancers. PMID: 24304275 Ref: Disease progression from chronic hepatitis C to cirrhosis and hepatocellular carcinoma is associated with increasing DNA promoter methylation. PMID: 24377595 Ref: Nutlin-3 overcomes arsenic trioxide resistance and tumor metastasis mediated by mutant p53 in Hepatocellular Carcinoma. PMID: 24884809 Ref: CHOP mediates ASPP2-induced autophagic apoptosis in hepatoma cells by releasing Beclin-1 from Bcl-2 and inducing nuclear translocation of Bcl-2. PMID: 25032846 Ref: Piper betle leaf extracts induced human hepatocellular carcinoma Hep3B cell death via MAPKs regulating the p73 pathway in vitro and in vivo. PMID: 25371988 Ref: Methylation of multiple genes in hepatitis C virus associated hepatocellular carcinoma. PMID: 25685469 |
Ref: Chronic hepatitis C virus infection triggers spontaneous differential expression of biosignatures associated with T cell exhaustion and apoptosis signaling in peripheral blood mononucleocytes. PMID: 25577277 Ref: The p53R172H mutant does not enhance hepatocellular carcinoma development and progression. PMID: 25885474 |
Ref: Autophagy-related cell death by pan-histone deacetylase inhibition in liver cancer. PMID: 27058414 Ref: Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease. PMID: 27359056 Ref: Meta-analysis of DNA methylation biomarkers in hepatocellular carcinoma. PMID: 27835605 |
Ref: Matrineinduced apoptosis in Hep3B cells via the inhibition of MDM2. PMID: 27959389 Ref: Role of p63 and p73 isoforms on the cell death in patients with hepatocellular carcinoma submitted to orthotopic liver transplantation. PMID: 28350813 Ref: TP53INP1 Downregulation Activates a p73-Dependent DUSP10/ERK Signaling Pathway to Promote Metastasis of Hepatocellular Carcinoma. PMID: 28674078 Ref: Ccdc3: A New P63 Target Involved in Regulation Of Liver Lipid Metabolism. PMID: 28827783 |
Ref: si-TP73-AS1 suppressed proliferation and increased the chemotherapeutic response of GC cells to cisplatin. PMID: 30127981 Ref: Dimetallic Ru(II) arene complexes appended on bis-salicylaldimine induce cancer cell death and suppress invasion via p53-dependent signaling. PMID: 30282320 Ref: Aberrant expression of alternative isoforms of transcription factors in hepatocellular carcinoma. PMID: 30386458 |