Primary Site >> Pancreatic Cancer
Gene >> TP53
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Ref: Development of a transgenic mouse system for the analysis of stages in liver carcinogenesis using tissue-specific expression of SV40 large T-antigen controlled by regulatory elements of the human alpha-1-antitrypsin gene. PMID: 2551499 |
Ref: Growth factors and oncogenes in pancreatic cancer. PMID: 1964102 |
Ref: Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer. PMID: 1764370 |
Ref: Comparative immunohistochemical studies of p53 and proliferating cell nuclear antigen expression and argyrophilic nucleolar organizer regions in pancreatic duct cell carcinomas. PMID: 7901190 Ref: Immunohistochemical demonstration of the p53 tumour suppressor gene product in cancer of the pancreas and chronic pancreatitis. PMID: 8218996 Ref: Comparison of p53 protein expression and cellular localization in human and hamster pancreatic cancer cell lines. PMID: 8269631 Ref: p53 and K-RAS alterations in pancreatic epithelial cell lesions. PMID: 8426738 Ref: Detection of p53 overexpression in routinely paraffin-embedded tissue of human carcinomas using a novel target unmasking fluid. PMID: 8434637 Ref: Pancreatic adenocarcinomas frequently show p53 gene mutations. PMID: 8494051 Ref: p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis. PMID: 8513440 |
Ref: Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma. PMID: 7726912 Ref: Intraductal papillary-mucinous tumours represent a distinct group of pancreatic neoplasms: an investigation of tumour cell differentiation and K-ras, p53 and c-erbB-2 abnormalities in 26 patients. PMID: 7820300 Ref: Expression of p53 tumor suppressor gene, oncoprotein c-erbB-2, cellular proliferation and differentiation in malignant and benign pancreatic lesions. PMID: 7847827 Ref: p53 expression in human pancreatic cancer correlates with enhanced biological aggressiveness. PMID: 7872670 Ref: Detection of the anti-p53 antibody response in malignant and benign pancreatic disease. PMID: 7947080 Ref: [Lesions of the pancreatic duct epithelium and histogenesis of exocrine pancreatic carcinomas]. PMID: 7947629 Ref: Overexpression of heat shock protein (hsp) 70 associated with abnormal p53 expression in cancer of the pancreas. PMID: 7947633 Ref: [Establishment of a human pancreatic adenocarcinoma cell line(JF305) with p53 expression]. PMID: 7956694 Ref: Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer. PMID: 8026879 Ref: [Clinicopathological features and diagnostic points of uncommon pancreatic tumors]. PMID: 8139123 Ref: Detection of K-ras mutations in mucinous pancreatic duct hyperplasia from a patient with a family history of pancreatic carcinoma. PMID: 8178941 Ref: Allelotype analysis of esophageal squamous cell carcinoma. PMID: 8187088 Ref: p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions. PMID: 8187092 Ref: Immunohistochemical analysis of p53 expression in human pancreatic carcinomas. PMID: 8311654 Ref: Increased mdm2 expression and immunoreactivity in human pancreatic ductal adenocarcinoma. PMID: 21559710 Ref: Alterations of the p53 tumor-suppressor gene and ki-ras oncogene in human pancreatic cancer-derived cell-lines with different metastatic potential. PMID: 21607521 |
Ref: Interaction between murine germline mutations in p53 and APC predisposes to pancreatic neoplasia but not to increased intestinal malignancy. PMID: 7478622 Ref: Allelotype of pancreatic adenocarcinoma using xenograft enrichment. PMID: 7553647 Ref: Chemopreventive activity of Oltipraz against N-nitrosobis(2-oxopropyl)amine (BOP)-induced ductal pancreatic carcinoma development and effects on survival of Syrian golden hamsters. PMID: 7554069 Ref: p53-independent expression of the cyclin-dependent kinase inhibitor p21 in pancreatic carcinoma. PMID: 7573363 Ref: Can molecular markers now be used for early diagnosis of malignancy? PMID: 7586509 Ref: Familial pancreatic cancer and the genetics of pancreatic cancer. PMID: 7660249 Ref: Two different pituitary adenomas in a patient with multiple endocrine neoplasia type 1 associated with growth hormone-releasing hormone-producing pancreatic tumor: clinical and genetic features. PMID: 7670561 Ref: Antibodies against p53 protein in serum of patients with benign or malignant pancreatic and biliary diseases. PMID: 7698709 Ref: Molecular markers for diagnostic cytology of neoplasms in the head region of the pancreas: mutation of K-ras and overexpression of the p53 protein product. PMID: 7730480 Ref: Antisense oligonucleotides directed against p53 have antiproliferative effects unrelated to effects on p53 expression. PMID: 7880719 Ref: Mixed pleomorphic-osteoclast-like tumor of the pancreas. Light microscopical, immunohistochemical, and molecular biological studies. PMID: 8530833 |
Ref: p53, Ki-ras, and DNA ploidy in human pancreatic ductal adenocarcinomas. PMID: 8569192 Ref: Prognostic value of immunohistochemical expression of p53 in patients with pancreatic cancer. PMID: 8604235 Ref: Immunocytochemical detection of p53 protein from pancreatic duct brushings in patients with pancreatic carcinoma. PMID: 8635089 Ref: Pancreatic carcinoma in perspective. A continuing challenge. PMID: 8681296 Ref: Systemic and adjuvant therapy for patients with pancreatic carcinoma. PMID: 8681308 Ref: P53 protein expression in pancreatic tumors and its relationship to clinicopathological factors and prognosis. PMID: 8691842 Ref: Sensitive detection of loss of heterozygosity in the TP53 gene in pancreatic adenocarcinoma by fluorescence-based single-strand conformation polymorphism analysis using blunt-end DNA fragments. PMID: 8721679 Ref: K-ras mutation and p53 protein accumulation in intraductal mucin-hypersecreting neoplasms of the pancreas. PMID: 8740403 Ref: Lack of p53 immunoreactivity in pancreatic endocrine tumors. PMID: 8743819 Ref: Double cancer in a 74-year-old woman: a case report with genetic findings. PMID: 8804161 Ref: The role of anti-p53-autoantibodies in pancreatic disorders. PMID: 8807362 Ref: Pancreatic cancer: the potential clinical relevance of alterations in growth factors and their receptors. PMID: 8834768 Ref: Molecular oncology in pancreatic cancer. PMID: 8862512 Ref: p53 autoantibodies in patients with pancreatitis and pancreatic carcinoma. PMID: 8884844 Ref: p53 protein expression and DNA ploidy in cystic tumors of the pancreas. PMID: 8884845 Ref: Small pancreatic tubular adenocarcinomas: clinicopathological analysis with immunohistochemical and histochemical evaluation. PMID: 8893227 Ref: Signal transduction as target of gene therapy. PMID: 8893335 Ref: Ki-ras and p53 mutations in pancreatic ductal adenocarcinoma. PMID: 8927612 Ref: Orthotopic xenografts of human pancreatic carcinomas acquire genetic aberrations during dissemination in nude mice. PMID: 8971180 Ref: Concomitant point mutation of tumor suppressor gene p53 and oncogene c-N-ras in malignant neuroendocrine pancreatic tumor. PMID: 9042254 Ref: [Studies on MDM2 oncogene expression and its effect on pancreatic carcinoma cells]. PMID: 9275659 |
Ref: Advances in molecular genetics. PMID: 9046882 Ref: Hepatobiliary and pancreatic mucinous cystadenocarcinomas with mesenchymal stroma: analysis of estrogen receptors/progesterone receptors and expression of tumor-associated antigens. PMID: 9110301 Ref: Tumor-suppressive pathways in pancreatic carcinoma. PMID: 9135016 Ref: Inability to induce the alteration of tumorigenicity and chemosensitivity of p53-null human pancreatic carcinoma cells after the transduction of wild-type p53 gene. PMID: 9137421 Ref: Overexpression of p53 protein during pancreatitis. PMID: 9166944 Ref: Immunocytochemical detection of p53 protein as an adjunct in cytologic diagnosis from pancreatic duct brushings in mucin-producing tumors of the pancreas. PMID: 9196015 Ref: Clinical significance of serum p53 antigen in patients with pancreatic carcinomas. PMID: 9203945 Ref: Weekly paclitaxel as a radiation sensitizer for locally advanced gastric and pancreatic cancers: the Brown University Oncology Group experience. PMID: 9206986 Ref: Prevalence and clinical significance of combined K-ras mutation and p53 aberration in pancreatic adenocarcinoma. PMID: 9209954 Ref: Prognostic significance of Ki-67 antigen and p53 protein expression in pancreatic duct carcinoma: a study of the monoclonal antibodies MIB-1 and DO-7 in formalin-fixed paraffin-embedded tumour material. PMID: 9218733 Ref: Molecular diagnosis of pancreas carcinoma. PMID: 9219065 Ref: The clinical significance of p21(WAF1/CIP-1) and p53 expression in pancreatic adenocarcinoma. PMID: 9241070 Ref: Nuclear accumulation of p53 correlates significantly with clinical features and inversely with the expression of the cyclin-dependent kinase inhibitor p21(WAF1/CIP1) in pancreatic cancer. PMID: 9252195 Ref: p53 protein expression as prognostic factor in human pancreatic cancer. PMID: 9252715 Ref: [Molecular diagnosis of pancreatic cancer]. PMID: 9276865 Ref: Relationship of family cancer history to the expression of p53, p21WAF-1, HER-2/neu, and K-ras mutation in pancreatic adenocarcinoma. PMID: 9322121 Ref: Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor. PMID: 9331070 Ref: The geranylgeranyltransferase-I inhibitor GGTI-298 arrests human tumor cells in G0/G1 and induces p21(WAF1/CIP1/SDI1) in a p53-independent manner. PMID: 9341167 Ref: The molecular genetics of pancreatic cancer. PMID: 9364657 Ref: Molecular advances in pancreatic cancer. PMID: 9438601 Ref: Molecular versus conventional markers in pancreatic cancer. PMID: 9438602 Ref: Advances in the early detection, diagnosis, and staging of pancreatic cancer. PMID: 9576631 |
Ref: Genetics of pancreatic cancer. From genes to families. PMID: 9443984 Ref: The plasminogen activator system in pancreas cancer: role of t-PA in the invasive potential in vitro. PMID: 9482108 Ref: Inhibition of pancreatic tumor cell growth in culture by p21WAF1 recombinant adenovirus. PMID: 9510131 Ref: Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas and periampullary region. PMID: 9529019 Ref: Genetic alterations in chronic pancreatitis: evidence for early occurrence of p53 but not K-ras mutations. PMID: 9529487 Ref: Aberrant p16INK4 expression related to clinical stage and prognosis in patients with pancreatic cancer. PMID: 9538137 Ref: The establishment of a preoperative diagnosis of pancreatic carcinoma using cell specimens from pancreatic duct brushing with special attention to p53 mutations. PMID: 9554525 Ref: An orthotopic model of human pancreatic cancer in severe combined immunodeficient mice: potential application for preclinical studies. PMID: 9563882 Ref: Clinical contribution of bcl-2, p53 and Ki-67 proteins in pancreatic ductal adenocarcinoma. PMID: 9568186 Ref: Stable reintroduction of wild-type P53 (MTmp53ts) causes the induction of apoptosis and neuroendocrine-like differentiation in human ductal pancreatic carcinoma cells. PMID: 9569027 Ref: Infrequent expression of p21 is related to altered p53 protein in pancreatic carcinoma. PMID: 9607571 Ref: Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene. PMID: 9622070 Ref: Targeting p53 for adoptive T-cell immunotherapy. PMID: 9635585 Ref: K-ras mutation in focal proliferative lesions of human pancreas. PMID: 9641496 Ref: Molecular pattern of ductal pancreatic cancer. PMID: 9641882 Ref: Prognostic significance of molecular alterations in human pancreatic carcinoma--an immunohistological study. PMID: 9641888 Ref: An immunohistochemical study of bcl-2 and p53 protein expression in pancreatic carcinomas. PMID: 9648995 Ref: Detection of Ki-ras and p53 gene mutations in tissue and pancreatic juice from pancreatic adenocarcinomas. PMID: 9658319 Ref: Analysis of p53, p21WAF1, and TGF-beta1 in human ductal adenocarcinoma of the pancreas: TGF-beta1 protein expression predicts longer survival. PMID: 9661918 Ref: Accumulation of genetic alterations and their significance in each primary human cancer and cell line. PMID: 9685701 Ref: An exogenous cdk inhibitor, butyrolactone-I, induces apoptosis with increased Bax/Bcl-2 ratio in p53-mutated pancreatic cancer cells. PMID: 9703910 Ref: Recent discoveries in cancer genetics of exocrine pancreatic neoplasia. PMID: 9705534 Ref: Gene therapy for primary and metastatic pancreatic cancer with intraperitoneal retroviral vector bearing the wild-type p53 gene. PMID: 9706132 Ref: Role of p53 tumor suppressor gene in pancreatic endocrine tumors of Chinese patients. PMID: 9707043 Ref: The expression of the KAI1 gene, a tumor metastasis suppressor, is directly activated by p53. PMID: 9736732 Ref: [Adenocarcinoma of the pancreas. General characteristics]. PMID: 9767968 Ref: Growth inhibition of pancreatic tumor cells by modified antisense oligodeoxynucleotides. PMID: 9776455 Ref: Osteoclast-like giant cell tumor of the pancreas with metastases to gallbladder and lymph nodes. A case report. PMID: 9779494 Ref: The promoter of human p22/PACAP response gene 1 (PRG1) contains functional binding sites for the p53 tumor suppressor and for NFkappaB. PMID: 9781666 Ref: Comparative study of p53 expression in primary invasive ductal carcinoma of the pancreas between Chinese and Japanese. PMID: 9788535 Ref: Gene therapy and pancreatic cancer. PMID: 9792901 Ref: Paclitaxel and concurrent radiation for locally advanced pancreatic carcinoma. PMID: 9792903 Ref: Restriction digest PCR (RD-PCR) for the analysis of gene mutations. Application to Ki-ras. PMID: 9806467 Ref: The molecular and cellular biology of pancreatic cancer. PMID: 9807701 Ref: Current concepts in pancreatic cancer: symposium summary. PMID: 9821173 Ref: A novel strategy for inhibiting growth of human pancreatic cancer cells by blocking cyclin-dependent kinase activity. PMID: 9841966 Ref: Inactivation of the p53 tumor suppressor gene via a novel Alu rearrangement. PMID: 9850060 Ref: Generation of fiber-mutant recombinant adenoviruses for gene therapy of malignant glioma. PMID: 9853517 Ref: p53 expression affects the efficacy of adjuvant chemotherapy after resection of invasive ductal carcinoma of the pancreas. PMID: 9854494 Ref: Pancreatic cancer associated with granulocyte-colony stimulating factor production confirmed by immunohistochemistry. PMID: 9855271 Ref: Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer [seecomments]. PMID: 9869513 Ref: Pancreatic endocrine tumours: evidence for a tumour suppressor pathogenesis and for a tumour suppressor gene on chromosome 17p. PMID: 9875139 Ref: Molecular alterations associated with improved survival in pancreatic cancer patients treated with radiation or chemotherapy. PMID: 9880774 Ref: 9-Hydroxyellipticine inhibits telomerase activity in human pancreatic cancer cells. PMID: 9883907 Ref: Ki-ras and p53 gene mutations in pancreatic ductal carcinoma: a relationship with tumor phenotype and survival. PMID: 10076772 Ref: Pancreatic cancer and fibrinogen storage disease. PMID: 10193333 Ref: [Apoptosis induced by adenovirus-mediated wild-type p53 expression in human pancreatic cancer cells]. PMID: 11244980 Ref: Inhibiting effect of murine double minute-2 oncogene on apoptosis induced by retroviral-mediated wild-type p53. PMID: 11263374 Ref: [Murine Doube Minute 2 oncogene inhibited apoptosis induced by retroviral-mediated wild-type p53]. PMID: 11717930 Ref: [The effect of adenovirus-mediated wild-type p53 expression on the growth of human pancreatic carcinoma cell line cells]. PMID: 11717990 Ref: [Prognostic value of molecular biologogy and immunologic parameters in human pancreatic carcinoma]. PMID: 14518215 |
Ref: Clinical significance of circulating anti-p53 antibodies in European patients with hepatocellular carcinoma. PMID: 10027337 Ref: Immunohistochemical evaluation of K-ras, p53, and HER-2/neu expression in hyperplastic, dysplastic, and carcinomatous lesions of the pancreas: evidence for multistep carcinogenesis. PMID: 10029438 Ref: Utility of fluorescence in situ hybridization in pancreatic ductal adenocarcinoma. PMID: 10090407 Ref: Comparative significance of p53 and WAF/1-p21 expression on the efficacy of adjuvant chemotherapy for resectable invasive ductal carcinoma of the pancreas. PMID: 10090408 Ref: Characterization of six cell lines established from human pancreatic adenocarcinomas. PMID: 10091760 Ref: Immunohistochemical and molecular analysis of giant cell carcinoma of the pancreas: a report of three cases. PMID: 10206490 Ref: Role of p53 and p16 gene alterations in determining response to concurrent paclitaxel and radiation in solid tumor. PMID: 10210535 Ref: Paclitaxel and concurrent radiation therapy for locally advanced adenocarcinomas of the pancreas, stomach, and gastroesophageal junction. PMID: 10210540 Ref: Patterns of genetic alterations in pancreatic cancer: a pooled analysis. PMID: 10217065 Ref: Infrequent somatic mutations of the p73 gene in various human cancers. PMID: 10218465 Ref: Clinical and biological features of t1 ductal adenocarcinoma of the pancreas. PMID: 10228850 Ref: Induction of growth inhibition and apoptosis in pancreatic cancer cells by auristatin-PE and gemcitabine. PMID: 10341297 Ref: Detection of mutations of p53 tumor suppressor gene in pancreatic juice and its application to diagnosis of patients with pancreatic cancer: comparison with K-ras mutation. PMID: 10353750 Ref: Malignant fibrous histiocytoma of the pancreas: a case report with genetic analysis. PMID: 10357405 Ref: Bcl-2 expression related to altered p53 protein and its impact on the progression of human pancreatic carcinoma. PMID: 10362119 Ref: Prognosis of human pancreatic adenocarcinoma: review of clinical and histopathological variables and possible uses of new molecular methods. PMID: 10365829 Ref: Molecular pathology of invasive carcinoma. PMID: 10415852 Ref: Orthotopic models of human pancreatic cancer. PMID: 10415855 Ref: Growth factors and cytokines in pancreatic carcinogenesis. PMID: 10415856 Ref: p53 in relation to therapeutic outcome of locoregional chemotherapy in pancreatic cancer. PMID: 10415873 Ref: The gene for multiple endocrine neoplasia type 1: recent findings. PMID: 10423035 Ref: Progress in cancer genetics: lessons from pancreatic cancer. PMID: 10436774 Ref: Pathology of incipient pancreatic cancer. PMID: 10436775 Ref: Role of tumor markers and mutations in cells and pancreatic juice in the diagnosis of pancreatic cancer. PMID: 10436798 Ref: Diagnosis of pancreatico-biliary malignancy: detection of gene mutations in plasma and stool. PMID: 10436800 Ref: Role of tumour markers, cytogenetics. PMID: 10436809 Ref: Biliopancreatic malignancy: screening the at risk patient with molecular markers. PMID: 10436811 Ref: The future of surgery for pancreatic cancer. PMID: 10436842 Ref: Biliopancreatic malignancy: future prospects for progress. PMID: 10436845 Ref: Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus. PMID: 10445844 Ref: Molecular aspects of pancreatic cancer and future perspectives. PMID: 10449972 Ref: Implication of vascular endothelial growth factor in the development and metastasis of human cancers. PMID: 10457902 Ref: Ras mutation, irrespective of cell type and p53 status, determines a cell's destiny to undergo apoptosis by okadaic acid, an inhibitor of protein phosphatase 1 and 2A. PMID: 10462539 Ref: Adenovirus-mediated p53 gene transduction inhibits telomerase activity independent of its effects on cell cycle arrest and apoptosis in human pancreatic cancer cells. PMID: 10473098 Ref: An orthotopic in vivo model of human pancreatic cancer. PMID: 10486610 Ref: Genetic background determines the response to adenovirus-mediated wild-type p53 expression in pancreatic tumor cells. PMID: 10505853 Ref: Pancreatic solid-cystic-papillary tumor: clinicopathologic features in eight patients from Hong Kong and review of the literature. PMID: 10512945 Ref: Ki-ras codon 12 point mutation and p53 mutation in pancreatic diseases. PMID: 10522044 Ref: Sequential accumulation of K-ras mutations and p53 overexpression in the progression of pancreatic mucinous cystic neoplasms to malignancy. PMID: 10522720 Ref: Molecular effects of taxol and caffeine on pancreatic cancer cells. PMID: 10534572 Ref: Diagnostic p53 immunostaining of endobiliary brush cytology: preoperative cytology compared with the surgical specimen. PMID: 10536357 Ref: Clonal preservation of human pancreatic cell line derived from primary pancreatic adenocarcinoma. PMID: 10547195 Ref: Molecular mechanism involved in increased expression of sialyl Lewis antigens in ductal carcinoma of the pancreas. PMID: 10606190 Ref: CD44 isoforms expression in intraductal and invasive pancreatic cancer and its correlation to p53 gene mutations. PMID: 10624116 Ref: Angiogenesis and p53 and H-ras mutations in pancreatic ductal adenocarcinoma. PMID: 10626015 Ref: Role of Bcl-2 family proteins (Bax, Bcl-2 and Bcl-X) on cellular susceptibility to radiation in pancreatic cancer cells. PMID: 10658530 Ref: An immunohistochemical study of the expression of bcl-2 and p53 oncoproteins in pancreatic intraepithelial neoplasia and pancreatic cancer. PMID: 10732293 Ref: Molecular genetics and related developments in pancreatic cancer. PMID: 17023981 |
Ref: Molecular biology of pancreatic cancer; oncogenes, tumour suppressor genes, growth factors, and their receptors from a clinical perspective. PMID: 10660490 Ref: [General rules for the study of pancreatic cancer by molecular biological aspect]. PMID: 10734643 Ref: Diverse effects of 9-hydroxyellipticine on the chemosensitivity of human pancreatic cancer cells harboring p53 mutations. PMID: 10737712 Ref: Ki-ras point mutation and p53 expression in human pancreatic cancer: a comparative study among Chinese, Japanese, and Western patients. PMID: 10750666 Ref: Foamy gland pattern of pancreatic ductal adenocarcinoma: a deceptively benign-appearing variant. PMID: 10757396 Ref: Actinomycin D induces apoptosis and inhibits growth of pancreatic cancer cells. PMID: 10760829 Ref: Pancreatic cancer cell proliferation is phosphatidylinositol 3-kinase dependent. PMID: 10781373 Ref: Modulation of drug cytotoxicity by reintroduction of wild-type p53 gene (Ad5CMV-p53) in human pancreatic cancer. PMID: 10811472 Ref: Characterization of a newly established human pancreatic carcinoma cell line, UK Pan-1. PMID: 10813711 Ref: Current approaches and future strategies for pancreatic carcinoma. PMID: 10830140 Ref: Overexpression and localization of heat shock proteins mRNA in pancreatic carcinoma. PMID: 10851351 Ref: Ductal lesions in patients with chronic pancreatitis show K-ras mutations in a frequency similar to that in the normal pancreas and lack nuclear immunoreactivity for p53. PMID: 10861425 Ref: Molecular analysis of microdissected tumors and preneoplastic intraductal lesions in pancreatic carcinoma. PMID: 10880379 Ref: Treatment of ras-induced cancers by the F-actin-bundling drug MKT-077. PMID: 10882332 Ref: K-ras gene mutations and loss of heterozygosity at the p53 gene locus relative to histological characteristics of mucin-producing tumors of the pancreas. PMID: 10923915 Ref: Noninvasive and minimally invasive papillary carcinomas of the extrahepatic bile ducts. PMID: 10931449 Ref: Ki-ras codon 12 point and P53 mutations: a molecular examination of the main tumor, liver, portal vein, peripheral arterial blood and para-aortic lymph node in pancreatic cancer. PMID: 10950039 Ref: Association of poor prognosis with loss of 12q, 17p, and 18q, and concordant loss of 6q/17p and 12q/18q in human pancreatic ductal adenocarcinoma. PMID: 10950061 Ref: p21WAF1 expression is associated with improved survival after adjuvant chemoradiation for pancreatic cancer. PMID: 11015084 Ref: p53 protein expression in intraductal papillary mucinous tumors (IPMT) of the pancreas as an indicator of tumor malignancy. PMID: 11020860 Ref: Multiple primary tumors as an indicator for p16INK4a germline mutations in pancreatic cancer patients? PMID: 11075991 Ref: Pancreatic cancer--new aspects of molecular biology research. PMID: 11077487 Ref: K-ras and p53 in pancreatic cancer: association with medical history, histopathology, and environmental exposures in a population-based study. PMID: 11097231 Ref: Intraductal papillary mucinous tumors: a case report and review of literature. PMID: 11125631 Ref: Tumor angiogenesis as a prognostic predictor in pancreatic cancer. PMID: 11180876 Ref: The physiology of p16(INK4A)-mediated G1 proliferative arrest. PMID: 11325039 Ref: [Somatostatin receptor subtype 2 mRNA expression in human gastric immortalized cell line and tumor cell lines]. PMID: 12903435 Ref: Molecular genetics of ductal pancreatic neoplasia. PMID: 17031113 |
Ref: Characterization of the mutations of the K-ras, p53, p16, and SMAD4 genes in 15 human pancreatic cancer cell lines. PMID: 11115575 Ref: Growth factors and their receptors in pancreatic cancer. PMID: 11135319 Ref: Colloid (mucinous noncystic) carcinoma of the pancreas. PMID: 11145249 Ref: Pancreatic tumours: molecular pathways implicated in ductal cancer are involved in ampullary but not in exocrine nonductal or endocrine tumorigenesis. PMID: 11161385 Ref: [Development of gene therapy for pancreatic cancer]. PMID: 11197871 Ref: Combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and actinomycin D induces apoptosis even in TRAIL-resistant human pancreatic cancer cells. PMID: 11234897 Ref: Deregulated expression of cell cycle-associated proteins in solid pseudopapillary tumor of the pancreas. PMID: 11235905 Ref: Low frequency of p53 and ras mutations in bile of patients with hepato-biliary disease: a prospective study in more than 100 patients. PMID: 11264652 Ref: Neoplasms of the ampulla of vater with concurrent pancreatic intraductal neoplasia: a histological and molecular study. PMID: 11266517 Ref: Caspase-3 activation downstream from reactive oxygen species in heat-induced apoptosis of pancreatic carcinoma cells carrying a mutant p53 gene. PMID: 11291926 Ref: Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability. PMID: 11306499 Ref: Treatment based on a combination of the CYP2B1/cyclophosphamide system and p53 delivery enhances tumour regression in human pancreatic cancer. PMID: 11332152 Ref: CD95-related apoptotic machinery is functional in pancreatic cancer cells. PMID: 11345135 Ref: An immunostaining panel for diagnosis of malignancy in mucinous tumors of the pancreas. PMID: 11371228 Ref: p53 and K-ras mutations in pancreatic juice samples from patients with chronic pancreatitis. PMID: 11375580 Ref: Carcinogenesis of cancer of the papilla and ampulla: pathophysiological facts and molecular biological mechanisms. PMID: 11382316 Ref: Copy number of cancer genes predict tumor grade and survival of pancreatic cancer patients. PMID: 11396207 Ref: Immunohistochemical study of genetic alterations in intraductal and invasive ductal tumors of the pancreas. PMID: 11462947 Ref: Tumor suppressor genes in the 9p21 gene cluster are selective targets of inactivation in neuroendocrine gastroenteropancreatic tumors. PMID: 11479232 Ref: Molecular diagnosis of pancreatic cancer. PMID: 11490843 Ref: Mechanism of growth-inhibitory effect of cisplatin on human pancreatic cancer cells and status of p53 gene. PMID: 11497278 Ref: Antineoplastic activity of novel N-1-sulfonypyrimidine derivatives. PMID: 11497287 Ref: Relative frequency and morphology of cancers in carriers of germline TP53 mutations. PMID: 11498785 Ref: Molecular biology of pancreatic cancer: potential clinical implications. PMID: 11520255 Ref: Bcl-2 expression in pancreas development and pancreatic cancer progression. PMID: 11523052 Ref: Molecular pathology of pancreatic cancer. PMID: 11561601 Ref: Molecular epidemiology of pancreatic cancer. PMID: 11561602 Ref: Novel therapies for pancreatic cancer. PMID: 11561610 Ref: Distinctive molecular genetic alterations in sporadic and familial adenomatous polyposis-associated pancreatoblastomas : frequent alterations in the APC/beta-catenin pathway and chromosome 11p. PMID: 11696422 Ref: Angiogenesis in pancreatic carcinoma: thymidine phosphorylase expression in stromal cells and intratumoral microvessel density as independent predictors of overall and relapse-free survival. PMID: 11745251 Ref: Overexpression of p21(WAF1/CIP1) is an early event in the development of pancreatic intraepithelial neoplasia. PMID: 11751405 Ref: [An application value of detecting K-ras and p53 gene mutation in the stool and pure pancreatic juice for diagnosis of early pancreatic cancer]. PMID: 11758254 Ref: Oncogenes, growth factors, receptor expression and proliferation markers in digestive neuroendocrine tumours. A critical reappraisal. PMID: 11762339 Ref: Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4. PMID: 11787853 Ref: ONYX-015. Onyx Pharmaceuticals. PMID: 11892945 Ref: An Epidemiological Overview of Environmental and Genetic Risk Factors of Pancreatic Cancer. PMID: 12718618 |
Ref: Restoration of transforming growth factor-beta signaling enhances radiosensitivity by altering the Bcl-2/Bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2. PMID: 11694525 Ref: p16INK4a is a prognostic marker in resected ductal pancreatic cancer: an analysis of p16INK4a, p53, MDM2, an Rb. PMID: 11753042 Ref: Paucity of dendritic cells in pancreatic cancer. PMID: 11854690 Ref: Genetic and immunohistochemical analysis of pancreatic acinar cell carcinoma: frequent allelic loss on chromosome 11p and alterations in the APC/beta-catenin pathway. PMID: 11891193 Ref: The mucin profile of noninvasive and invasive mucinous cystic neoplasms of the pancreas. PMID: 11914624 Ref: Solid-pseudopapillary tumors of the pancreas are genetically distinct from pancreatic ductal adenocarcinomas and almost always harbor beta-catenin mutations. PMID: 11943721 Ref: Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma. PMID: 11953819 Ref: Aberrant p16(INK4A) and DPC4/Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma. PMID: 12010891 Ref: Influence of p53 status on radiation and 5-flourouracil synergy in pancreatic cancer cells. PMID: 12014658 Ref: Molecular prognostic markers in pancreatic cancer. PMID: 12021893 Ref: Gene therapy for pancreatic cancer based on genetic characterization of the disease. PMID: 12021895 Ref: Genetic diagnosis of pancreatic cancer. PMID: 12021896 Ref: Establishment and characterization of four human pancreatic carcinoma cell lines. Genetic alterations in the TGFBR2 gene but not in the MADH4 gene. PMID: 12037578 Ref: Molecular pathogenesis of pancreatic cancer. PMID: 12063826 Ref: Regional chemotherapy. PMID: 12063827 Ref: E2F-1 gene therapy induces apoptosis and increases chemosensitivity in human pancreatic carcinoma cells. PMID: 12065845 Ref: Association of matrilysin expression with progression and poor prognosis in human pancreatic adenocarcinoma. PMID: 12066203 Ref: Genetic basis of pancreatic cancer. PMID: 12079267 Ref: [Genetics of pancreatic cancer: recent advances in molecular diagnosis]. PMID: 12094699 Ref: Monitoring daunorubicin-induced alterations in protein expression in pancreas carcinoma cells by two-dimensional gel electrophoresis. PMID: 12112851 Ref: Mixed ductal-pancreatic polypeptide-cell carcinoma of the pancreas. PMID: 12147089 Ref: Clinicopathological significance of abnormalities in Gadd45 expression and its relationship to p53 in human pancreatic cancer. PMID: 12171884 Ref: Papillary solid and cystic pancreatic tumor. Genetic prediction factors for malignancy: report of three cases. PMID: 12174924 Ref: Chemosensitization by fibroblast growth factor-2 is not dependent upon proliferation, S-phase accumulation, or p53 status. PMID: 12234614 Ref: Expression of vascular endothelial growth factor and p53 in pancreatic carcinomas. PMID: 12298426 Ref: Fas and Fas ligand expression in pancreatic adenocarcinoma. PMID: 12370548 Ref: The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK. PMID: 12384795 Ref: DPC4/Smad4 expression and outcome in pancreatic ductal adenocarcinoma. PMID: 12454109 Ref: [Molecular pathways of pancreatic carcinogenesis]. PMID: 12483152 Ref: Differential mechanisms of constitutive Akt/PKB activation and its influence on gene expression in pancreatic cancer cells. PMID: 12495471 Ref: Detecting K-ras and p53 gene mutation from stool and pancreatic juice for diagnosis of early pancreatic cancer. PMID: 12609076 Ref: Regulation of epithelial cell growth by ZBP-89: potential relevance in pancreatic cancer. PMID: 12622418 Ref: Clinical implication of anti-p53 antibodies and p53-protein in pancreatic disease. PMID: 12622424 Ref: Minute invasive ductal carcinoma of the residual pancreas after distal pancreatectomy for intraductal papillary-mucinous tumor. PMID: 12622431 Ref: Biological factors and therapeutic modulation in pancreatic carcinoma radiotherapy. PMID: 12696252 Ref: Gene therapy for pancreatic cancer targeting the genomic alterations of tumor suppressor genes using replication-selective oncolytic adenovirus. PMID: 12703544 Ref: Histopathological study of intraductal papillary mucinous tumor of the pancreas: special reference to the roles of Survivin and p53 in tumorigenesis of IPMT. PMID: 12794243 Ref: Clinical significance of expression of p21 and p53 proteins and proliferating cell nuclear antigen in pancreatic cancer. PMID: 14612290 |
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