Primary Site >> Pancreatic Cancer

Gene >> TOP2A

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Ref: Multicomponent analysis of the pancreatic adenocarcinoma progression model using a pancreatic intraepithelial neoplasia tissue microarray.
PMID: 13679454
Ref: A subset of pancreatic adenocarcinomas demonstrates coamplification of topoisomerase IIalpha and HER2/neu: use of immunolabeling and multicolor FISH for potential patient screening andtreatment.
PMID: 15762277
Ref: Modulation of cell cycle and gene expression in pancreatic tumor cell lines by methionine deprivation (methionine stress): implications to the therapy of pancreatic adenocarcinoma.
PMID: 16170025
Ref: [Topoisomerase IIalpha and HER2/neu gene alterations and their correlation in pancreatic ductal adenocarcinomas].
PMID: 17493384
Ref: Gene expression analysis for predicting gemcitabine sensitivity in pancreatic cancer patients.
PMID: 18333132
Ref: Adenosquamous carcinoma of the pancreas: Molecular characterization of 23 patients along with a literature review.
PMID: 26380056
Ref: Use of molecular studies for treatment of metastatic pleomorphic large cell pancreatic cancers-a novel strategy.
PMID: 27034802
Ref: The Natural Flavonoid Fisetin Inhibits Cellular Proliferation of Hepatic, Colorectal, and Pancreatic Cancer Cells through Modulation of Multiple Signaling Pathways.
PMID: 28052097
Ref: Nanoparticle-based hyperthermia distinctly impacts production of ROS, expression of Ki-67, TOP2A, and TPX2, and induction of apoptosis in pancreatic cancer.
PMID: 28223795
Ref: Integrated clinicopathological features and gene microarray analysis of pancreatic neuroendocrine tumors.
PMID: 28479381
Ref: Topoisomerase expression and amplification in solid tumours: Analysis of 24,262 patients.
PMID: 28728050
Ref: TOP2A induces malignant character of pancreatic cancer through activating beta-catenin signaling pathway.
PMID: 29045811
Ref: The growth inhibitory effect of gambogic acid on pancreatic cancer cells.
PMID: 29546614