Primary Site >> Colorectal Cancer
Gene >> TNS4
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Ref: C-terminal Tensin-like (CTEN) is an oncogene which alters cell motility possibly through repression of E-cadherin in colorectal cancer. PMID: 19214987 Ref: Up-regulation of C-terminal tensin-like molecule promotes the tumorigenicity of colon cancer through beta-catenin. PMID: 19487278 |
Ref: Cten signals through integrin-linked kinase (ILK) and may promote metastasis in colorectal cancer. PMID: 21339732 Ref: Cten is targeted by Kras signalling to regulate cell motility in the colon and pancreas. PMID: 21698197 |
Ref: Tensin-4-dependent MET stabilization is essential for survival and proliferation in carcinoma cells. PMID: 24814316 Ref: A mechanically-induced colon cancer cell population shows increased metastatic potential. PMID: 24884630 Ref: Nuclear expression of phosphorylated focal adhesion kinase is associated with poor prognosis in human colorectal cancer. PMID: 25075018 |
Ref: Multiple pathways regulate Cten in colorectal cancer without a Tensin switch. PMID: 26852686 |
Ref: Cten promotes epithelial-mesenchymal transition through the post-transcriptional stabilization of Snail. PMID: 28691764 |