Primary Site >> Colorectal Cancer

Gene >> TNFSF12

  • 2002
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  • 2017
  • 2018
Ref: Death of HT29 adenocarcinoma cells induced by TNF family receptor activation is caspase-independent and displays features of both apoptosis and necrosis.
PMID: 12478469
Ref: Soluble tumor necrosis factor-like weak inducer of apoptosis overexpression in HEK293 cells promotes tumor growth and angiogenesis in athymic nude mice.
PMID: 15604260
Ref: PPARgamma ligand 15-deoxy-delta 12,14-prostaglandin J2 sensitizes human colon carcinoma cells to TWEAK-induced apoptosis.
PMID: 20150631
Ref: Prognostic significance of TWEAK expression in colorectal cancer and effect of its inhibition on invasion.
PMID: 21681381
Ref: Interleukin-32 enhances cytotoxic effect of natural killer cells to cancer cells via activation of death receptor 3.
PMID: 22043900
Ref: The anti-Fn14 antibody BIIB036 inhibits tumor growth in xenografts and patient derived primary tumor models and enhances efficacy of chemotherapeutic agents in multiple xenograft models.
PMID: 22669574
Ref: Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-Mediated Destruction of Intestinal Epithelial Cells.
PMID: 27889570
Ref: Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice.
PMID: 28428709
Ref: [Prediction Value of TWEAK/Fn14 in Crohn's Disease with Intestinal Fibrosis].
PMID: 29130664
Ref: Differential Roles of Tumor Necrosis Factor Ligand Superfamily Members as Biomarkers in Pancreatic Cancer.
PMID: 30011858