Primary Site >> Colorectal Cancer

Gene >> TNFRSF9

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Ref: Immunomodulatory gene therapy with interleukin 12 and 4-1BB ligand: long- term remission of liver metastases in a mouse model.
PMID: 10841829
Ref: Rejection of disseminated metastases of colon carcinoma by synergism of IL-12 gene therapy and 4-1BB costimulation.
PMID: 10899826
Ref: Improving efficacy of interleukin-12-transfected dendritic cells injected into murine colon cancer with anti-CD137 monoclonal antibodies and alloantigens.
PMID: 15054868
Ref: Assessment expression of the adhesion molecules, CD134 and CD137, in patients with colorectal cancer by flow cytometry.
PMID: 15638367
Ref: Expression of CD137 and CD137 ligand in colorectal cancer patients.
PMID: 16596186
Ref: Targeted and untargeted CD137L fusion proteins for the immunotherapy of experimental solid tumors.
PMID: 17460060
Ref: Immunotherapy and immunoescape in colorectal cancer.
PMID: 17990348
Ref: Analysis of CD137 and CD137L expression in human primary tumor tissues.
PMID: 18461674
Ref: CD1d-based combination therapy eradicates established tumors in mice.
PMID: 19620318
Ref: Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2.
PMID: 20179677
Ref: Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ.
PMID: 20336294
Ref: Delivery of immunostimulatory monoclonal antibodies by encapsulated hybridoma cells.
PMID: 20607237
Ref: Intratumoral injection of interferon-alpha and systemic delivery of agonist anti-CD137 monoclonal antibodies synergize for immunotherapy.
PMID: 20309938
Ref: Determination of the activity of CD134 (OX-40) and CD137 (4-1BB) adhesive molecules by means of flow cytometry in patients with colorectal cancer metastases to the liver.
PMID: 22166715
Ref: Assessment of activity of an adhesion molecule CD134 and CD137 in colorectal cancer patients.
PMID: 22343199
Ref: The HIF-1alpha hypoxia response in tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy.
PMID: 22719018
Ref: PET imaging to non-invasively study immune activation leading to antitumor responses with a 4-1BB agonistic antibody.
PMID: 24829750
Ref: Routes of delivery for CpG and anti-CD137 for the treatment of orthotopic kidney tumors in mice.
PMID: 24788789
Ref: Targeting CD137 enhances the efficacy of cetuximab.
PMID: 24837434
Ref: Endothelial CD276 (B7-H3) expression is increased in human malignancies and distinguishes between normal and tumour-derived circulating endothelial cells.
PMID: 24892449
Ref: Combination anti-CD137 and anti-CD40 antibody therapy in murine myc-driven hematological cancers.
PMID: 24934848
Ref: Intermittent chemotherapy can retain the therapeutic potential of anti-CD137 antibody during the late tumor-bearing state.
PMID: 25363339
Ref: Immunotherapy of Colorectal Cancer.
PMID: 27259331
Ref: Abscopal Effects of Radiotherapy Are Enhanced by Combined Immunostimulatory mAbs and Are Dependent on CD8 T Cells and Crosspriming.
PMID: 27550452
Ref: Brachytherapy attains abscopal effects when combined with immunostimulatory monoclonal antibodies.
PMID: 28838649
Ref: Cetuximab Enhanced the Cytotoxic Activity of Immune Cells during Treatment of Colorectal Cancer.
PMID: 29179214
Ref: Deregulated Mucosal Immune Surveillance through Gut-Associated Regulatory T Cells and PD-1(+) T Cells in Human Colorectal Cancer.
PMID: 29581358