Primary Site >> Colorectal Cancer

Gene >> TNFRSF12A

  • 2004
  • 2012
  • 2014
  • 2016
  • 2017
Ref: Soluble tumor necrosis factor-like weak inducer of apoptosis overexpression in HEK293 cells promotes tumor growth and angiogenesis in athymic nude mice.
PMID: 15604260
 Ref: The anti-Fn14 antibody BIIB036 inhibits tumor growth in xenografts and patient derived primary tumor models and enhances efficacy of chemotherapeutic agents in multiple xenograft models.
PMID: 22669574
 Ref: A novel llama antibody targeting Fn14 exhibits anti-metastatic activity in vivo.
PMID: 24135629
 Ref: Protective Role for TWEAK/Fn14 in Regulating Acute Intestinal Inflammation and Colitis-Associated Tumorigenesis.
PMID: 27634763
 Ref: Immunotherapy for the treatment of colorectal tumors: focus on approved and in-clinical-trial monoclonal antibodies.
PMID: 28138221
Ref: Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice.
PMID: 28428709
Ref: [Prediction Value of TWEAK/Fn14 in Crohn's Disease with Intestinal Fibrosis].
PMID: 29130664