Primary Site >> Colorectal Cancer

Gene >> TNFRSF10C

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Ref: Reversible thrombocytopenia with levamisole.
PMID: 7700172
Ref: The TRAIL decoy receptor TRUNDD (DcR2, TRAIL-R4) is induced by adenovirus-p53 overexpression and can delay TRAIL-, p53-, and KILLER/DR5-dependent colon cancer apoptosis.
PMID: 10933923
Ref: Expression and function of death receptors and their natural ligands in the intestine.
PMID: 11193573
Ref: Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis.
PMID: 11245478
Ref: TRAIL and its receptors in the colonic epithelium: a putative role in the defense of viral infections.
PMID: 11874999
Ref: Expression of TRAIL and TRAIL receptors in colon carcinoma: TRAIL-R1 is an independent prognostic parameter.
PMID: 12473583
Ref: Expression of TRAIL (TNF-related apoptosis-inducing ligand) and its receptors in normal colonic mucosa, adenomas, and carcinomas.
PMID: 12845629
Ref: Differential modulation of the TRAIL receptors and the CD95 receptor in colon carcinoma cell lines.
PMID: 12865931
Ref: Increased sensitivity to TRAIL-induced apoptosis occurs during the adenoma to carcinoma transition of colorectal carcinogenesis.
PMID: 15685228
Ref: Chemotherapy and TRAIL-mediated colon cancer cell death: the roles of p53, TRAIL receptors, and c-FLIP.
PMID: 16373718
Ref: P53-mediated upregulation of DcR1 impairs oxaliplatin/TRAIL-induced synergistic anti-tumour potential in colon cancer cells.
PMID: 18345033
Ref: Long-term results of laparoscopic colorectal cancer resection.
PMID: 18425886
Ref: Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level.
PMID: 18590575
Ref: Prognostic significance of TRAIL-R1 and TRAIL-R3 expression in metastatic colorectal carcinomas.
PMID: 18755584
Ref: Hypoxia-induced decoy receptor 2 gene expression is regulated via a hypoxia-inducible factor 1alpha-mediated mechanism.
PMID: 20018172
Ref: Identification of novel methylation markers in hepatocellular carcinoma using a methylation array.
PMID: 20676325
Ref: Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNK.
PMID: 21156789
Ref: Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins.
PMID: 21797841
Ref: Casticin, a flavonoid, potentiates TRAIL-induced apoptosis through modulation of anti-apoptotic proteins and death receptor 5 in colon cancer cells.
PMID: 23135489
Ref: Evaluation of preventive and therapeutic activity of novel non-steroidal anti-inflammatory drug, CG100649, in colon cancer: Increased expression of TNF-related apoptosis-inducing ligand receptors enhance the apoptotic response to combination treatment wit
PMID: 25672292
Ref: TNFRSF10C copy number variation is associated with metastatic colorectal cancer.
PMID: 27284460
Ref: Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer.
PMID: 28968978
Ref: Comprehensive expression analysis of TNF-related apoptosis-inducing ligand and its receptors in colorectal cancer: Correlation with MAPK alterations and clinicopathological associations.
PMID: 29731264
Ref: TNFRSF10C methylation is a new epigenetic biomarker for colorectal cancer.
PMID: 30225159