Primary Site >> Liver Cancer
Gene >> TNF
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Ref: Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression. PMID: 2429991 Ref: Antitumor effect of human necrosis factor on human hepatoma cells PLC/PRF/5. PMID: 3102817 Ref: Recombinant human tumor necrosis factor--II. Antitumor effect on murine and human tumors transplanted in mice. PMID: 3525434 |
Ref: Action of recombinant human interleukin 6, interleukin 1 beta and tumor necrosis factor alpha on the mRNA induction of acute-phase proteins. PMID: 2454192 Ref: [Favorable response of advanced hepatocellular carcinoma to proper hepatic arterial administration of cytokines and the significance of the administration]. PMID: 2458070 Ref: Inhibitory effect of human recombinant interferon gamma on synthesis of acute phase proteins in human hepatoma Hep G2 cells stimulated by leukocyte cytokines, TNF alpha and IFN-beta 2/BSF-2/IL-6. PMID: 2461199 Ref: [Effects of TNF on human hepatocellular carcinoma cell lines and their modification by hyperthermia]. PMID: 2856500 Ref: TNF induces endogenous TNF in vivo: the basis of EET therapy as a combination of rTNF together with endogenous TNF. PMID: 3216223 |
Ref: [Recent trends in cancer treatment using cytokines]. PMID: 2471455 Ref: [Transcatheter arterial embolization with hepatic arterial induction of endogenous TNF in hepatocellular carcinoma]. PMID: 2476966 Ref: [Combination therapy of hyperthermia and other methods in liver and bile tract cancers--evaluation of these methods using cancer cell lines in vitro]. PMID: 2543327 Ref: [An immunological and clinical evaluation of combined TAE-LAK adoptive immunotherapy]. PMID: 2554034 Ref: [The metastatic tumor and immunotherapy]. PMID: 2730024 Ref: Antitumor effect of systemic administration of novel recombinant tumor necrosis factor (rTNF-S) with less toxicity than conventional rTNF-alpha in vivo. PMID: 2746298 |
Ref: [Treatment of liver metastatic ovarian cancer with sequential administration of OK-432 and etoposide]. PMID: 1963633 Ref: [A basic study of cytotoxic effect of tumor necrosis factor-alpha on the hepatoma cell line, PLC/PRF/5]. PMID: 2157910 Ref: [Chemoembolization combined with hepatic arterial induction of endogenous TNF and anticancer agents for hepatocellular carcinoma--a case report]. PMID: 2167647 |
Ref: Dexamethasone prevents the growth inhibitory effects of recombinant tumor necrosis factor in a rat hepatoma cell line Reuber-RC-3: an association with the changes in the messenger RNA levels for multidrug resistance gene. PMID: 1722406 Ref: Successful treatment of a case of hepatocellular carcinoma with tumor necrosis factor and local hyperthermia. PMID: 1722471 Ref: In vivo effects of human recombinant tumor necrosis factor alone and in combination with other biological response modifiers on human digestive organ cancer xenografts transplanted in nude mice. PMID: 1786197 Ref: Effects of cytokines on in vitro growth of tumor-infiltrating lymphocytes obtained from human primary and metastatic liver tumors. PMID: 1847844 Ref: Antitumor activity of a novel chimera tumor necrosis factor (TNF-STH) constructed by connecting rTNF-S with thymosin beta 4 against murine syngeneic tumors. PMID: 2043590 |
Ref: Interaction of interferon-alpha with interleukin-1 beta or tumor necrosis factor-alpha on hepatitis B virus enhancer activity. PMID: 1312844 Ref: Antiviral activity of tumor necrosis factor is signaled through the 55-kDa type I TNF receptor [corrected]. PMID: 1331233 Ref: BRM activities of low-toxic Bordetella pertussis lipopolysaccharides. PMID: 1414607 |
Ref: Tumor necrosis factor-alpha mediates changes in tissue protein turnover in a rat cancer cachexia model. PMID: 8254032 Ref: [Immunological effects of locoregional immunochemotherapy for liver metastases of gastric cancer]. PMID: 8373205 Ref: Tumor necrosis factor-alpha induces cell type and tissue-specific expression of chemoattractant cytokines in vivo. PMID: 8456945 |
Ref: [Tumor necrosis factor alpha levels in patients with chronic liver diseases and its relationship to pathogenesis]. PMID: 7712914 Ref: Dexamethasone inhibits induction of liver tumor necrosis factor-alpha mRNA and liver growth induced by lead nitrate and ethylene dibromide. PMID: 7943184 Ref: TNF-alpha effect on oxygen free radical scavenging and generating enzymes in rat liver. PMID: 8081209 Ref: Recombinant human tumor necrosis factor causes regression in patients with advanced malignancies. PMID: 8208522 Ref: Both type I and type II interferons down-regulate human tumor necrosis factor receptors in human hepatocellular carcinoma cell line Hep G2. Role of protein kinase C. PMID: 8276122 |
Ref: Dipyridamole combined with tumor necrosis factor-alpha enhances inhibition of proliferation in human tumor cell lines. PMID: 7559100 Ref: [Blood coagulation and fibrinolysis in relation to endotoxemia in liver cirrhosis and hepatocellular carcinoma]. PMID: 7563921 Ref: Experimental liver cancer: improved response after hepatic artery ligation and infusion of tumor necrosis factor-alpha and interferon-gamma. PMID: 7570335 Ref: Perturbations of triglycerides but not of cholesterol metabolism are prevented by anti-tumour necrosis factor treatment in rats bearing an ascites hepatoma (Yoshida AH-130). PMID: 7577459 Ref: [Preliminary studies on the effects of tumor necrosis factor gene transfer on the growth of human hepatocellular carcinoma cells in nude mice]. PMID: 7656817 Ref: Antitumor effects of intraarterial infusion of tumor necrosis factor/lipiodol emulsion on hepatic tumor in rabbits. PMID: 7800348 Ref: Tumour growth stimulation after partial hepatectomy can be reduced by treatment with tumour necrosis factor alpha. PMID: 7881931 Ref: Promotion of experimental liver metastasis by tumor necrosis factor. PMID: 7896459 Ref: Leukocyte activation by isolated hyperthermic liver and limb perfusion due to malignancy. PMID: 8553680 Ref: [Enhanced immune functions and antitumor activity of fibroblast-mediated interleukin-2 gene therapy]. PMID: 8556540 |
Ref: Systemic administration of a synthetic lipid A derivative, DT-5461a, reduces tumor blood flow through endogenous TNF production in hepatic cancer model of VX2 carcinoma in rabbits. PMID: 8615636 Ref: Tumor necrosis factor production in the perfused mouse liver and its pharmacological modulation by methylxanthines. PMID: 8786577 Ref: Augmented antitumor effects of killer cells induced by tumor necrosis factor gene-transduced autologous tumor cells from gastrointestinal cancer patients. PMID: 8894681 Ref: Modulation of EGF receptor by tumor necrosis factor-alpha in human hepatocellular carcinoma HepG2 cells. PMID: 8917420 Ref: Effects of antitumor activity and protection of shock symptoms by a traditional Chinese medicine (sho-saiko-to) in recombinant human tumor necrosis factor administered mice. PMID: 8951167 Ref: [Augmentation of liver immune functions by intrasplenic transplantation of IL-2 gene-modified hepatocytes]. PMID: 9275543 |
Ref: Alpha-fetoprotein as a TNF resistance factor for the human hepatocarcinoma cell line HepG2. PMID: 8989923 Ref: Complete regression of established murine hepatocellular carcinoma by in vivo tumor necrosis factor alpha gene transfer. PMID: 9024304 Ref: Tumor necrosis factor-induced apoptosis during the poisoning of mice with hepatotoxins. PMID: 9041255 Ref: Antibodies to tumor necrosis factor alpha prevent increases in cell replication in liver due to the potent peroxisome proliferator, WY-14,643. PMID: 9111198 Ref: Vesnarinone inhibits immune-mediated but not Fas (CD95) agonist-mediated hepatic injury. PMID: 9226479 Ref: Serum levels of IL-10, IL-15 and soluble tumour necrosis factor-alpha (TNF-alpha) receptors in type C chronic liver disease. PMID: 9328122 Ref: Quantitative and morphological changes in BAL-isolated cells after the administration of TNF-alpha into Morris hepatoma. PMID: 9337555 Ref: The mechanism of locally enhanced production of tumor necrosis factor-alpha in tumor tissues by the administration of a new synthetic lipid A analog, ONO-4007, in hepatoma-bearing rats. PMID: 9402316 Ref: Therapeutic effects of a new synthetic lipid A analog, ONO-4007, on rat hepatoma KDH-8 depend on tumor necrosis factor-sensitivity of the tumor cells. PMID: 9402318 Ref: Stimulation of tumor necrosis factor and interleukin-1 productivity by the oral administration of cabbage juice to rats. PMID: 9404076 |
Ref: TNF-alpha inhibits liver collagen-alpha 1(I) gene expression through a tissue-specific regulatory region. PMID: 9612264 Ref: A novel human tumor necrosis factor alfa mutein, F4614, inhibits in vitro and in vivo growth of murine and human hepatoma: implication for immunotherapy of human hepatocellular carcinoma. PMID: 9657097 Ref: Proinflammatory cytokines lowering erythropoietin production. PMID: 9726435 Ref: The hepatitis B virus X protein up-regulates tumor necrosis factor alpha gene expression in hepatocytes. PMID: 9755238 Ref: Serum and liver concentrations of tumor necrosis factor alpha and interleukin-1beta following administration of carbon tetrachloride to male rats. PMID: 9776568 Ref: Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in mice. PMID: 9828225 Ref: Association of serum tumor necrosis factor levels with decrease of cholesterol during septic shock. PMID: 9840652 Ref: Isolated hypoxic hepatic perfusion with tumor necrosis factor-alpha, melphalan, and mitomycin C using balloon catheter techniques: a pharmacokinetic study in pigs. PMID: 9860475 Ref: [The clinic significance of serum hyaluronate and tumor necrosis factor alpha levels in liver diseases]. PMID: 10681811 |
Ref: Tumor necrosis factor p55 receptor (TNF-RI) mediates the in vitro inhibition of hepatic erythropoietin production. PMID: 10029160 Ref: Effects of 5'-DFUR and lentinan on cytokines and PyNPase against AH66 ascites hepatoma in rats. PMID: 10226570 Ref: Fas (APO-1, CD95) receptor expression and new options for immunotherapy in childhood medulloblastomas. PMID: 10652626 Ref: Involvement of TNF-alpha in enhancement of invasion and metastasis of colon 26-L5 carcinoma cells in mice by social isolation stress. PMID: 10850887 Ref: [Cellular immune function influence on postoperative patients with hepatocellular carcinoma and the clinical effect of TILs treatment]. PMID: 11829765 |
Ref: Anti-tumor effects of 25-hydroxycholesterol and low-dose recombinant tumor necrosis factor-alpha on rat liver tumorigenesis: modulated differentiation therapy for hepatocellular carcinoma. PMID: 10762641 Ref: Ethanol potentiates tumor necrosis factor-alpha cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition. PMID: 10796891 Ref: Tumor necrosis factor-alpha augments tumor effects in isolated hepatic perfusion with melphalan in a rat sarcoma model. PMID: 10916754 Ref: A phase I-II study of isolated hepatic perfusion using melphalan with or without tumor necrosis factor for patients with ocular melanoma metastatic to liver. PMID: 10955785 Ref: Immunomodulation of Bu-Zhong-Yi-Qi-Tang on in vitro granulocyte colony-stimulating-factor and tumor necrosis factor-alpha production by peripheral blood mononuclear cells. PMID: 11105783 Ref: A new method of antitumor therapy with a high dose of TNF perfusion for unresectable liver tumors. PMID: 11131677 Ref: [Targeting studies of humanized scFv25 fusing to TNFalpha against hepatocellular carcinoma]. PMID: 11135695 Ref: [Combined five tumor markers in detecting primary hepatic carcinoma]. PMID: 11831976 |
Ref: Effect of interferon-gamma on the susceptibility to Fas (CD95/APO-1)-mediated cell death in human hepatoma cells. PMID: 11315506 Ref: Tumor necrosis factor-alpha inhibits store-mediated Ca2+ entry in the human hepatocellular carcinoma cell line HepG2. PMID: 11350760 Ref: Role of FAK in TNF-alpha/Cycloheximide-induced Apoptosis of SMMC-7721 Cells. PMID: 12053189 Ref: [Level change of IL-10, IL-12 and TNF alpha in the serun of patients with hepatocellular carcinoma]. PMID: 12536618 |
Ref: Development and application of an isolated perfused rat liver model to study the stimulation and inhibition of tumor necrosis factor-alpha production ex vivo. PMID: 11837700 Ref: Hepatitis C virus NS5A protein impairs TNF-mediated hepatic apoptosis, but not by an anti-FAS antibody, in transgenic mice. PMID: 11886269 Ref: Locoregional immuno(bio)therapy for liver metastases. PMID: 11951214 Ref: Improved survival of TNF-deficient mice during the zymosan-induced multiple organ dysfunction syndrome. PMID: 12069182 Ref: Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin. PMID: 12085986 Ref: [Immune responses of dendritic cells after loaded with cytotoxicity T lymphocyte epitope based peptide of human alpha-fetoprotein (hAFP)]. PMID: 12113671 Ref: Antitumor effects of isolated hypoxic hepatic perfusion (IHHP) with high-dose TNF against colonic liver metastases in a rat model. PMID: 12174943 Ref: Inhibition of erythropoietin gene expression signaling involves the transcription factors GATA-2 and NF-kappaB. PMID: 12223449 Ref: Large volume hepatic freezing: association with significant release of the cytokines interleukin-6 and tumor necrosis factor a in a rat model. PMID: 12297923 Ref: Essential roles of tumor necrosis factor receptor p55 in liver metastasis of intrasplenic administration of colon 26 cells. PMID: 12438267 |
Ref: TNF-alpha downregulates vascular endothelial Flk-1 expression in human melanoma xenograft model. PMID: 12388254 Ref: Degree of tumour vascularity correlates with drug accumulation and tumour response upon TNF-alpha-based isolated hepatic perfusion. PMID: 12610519 Ref: Tumor necrosis factor alpha (TNF-alpha)-induced RANTES chemokine expression via activation of NF-kappaB and p38 MAP kinase: roles of TNF-alpha in alcoholic liver diseases. PMID: 12663241 Ref: Interleukin 10 haplotype associated with increased risk of hepatocellular carcinoma. PMID: 12668613 Ref: Selective up-regulation of tumor necrosis factor receptor I in tumor-bearing rats with cancer-related cachexia. PMID: 12851692 Ref: Tumor-targeted gene therapy: strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes. PMID: 12932649 Ref: Induction of human methionine adenosyltransferase 2A expression by tumor necrosis factor alpha. Role of NF-kappa B and AP-1. PMID: 14530285 Ref: 15-deoxy-delta-12-14-PGJ2 regulates apoptosis induction and nuclear factor-kappaB activation via a peroxisome proliferator-activated receptor-gamma-independent mechanism in hepatocellular carcinoma. PMID: 14563954 Ref: TNF-alpha induced DNA damage in primary murine hepatocytes. PMID: 14612962 Ref: Increased serum concentrations of tumor necrosis factor-alpha are associated with disease progression and malnutrition in hepatocellular carcinoma. PMID: 14703276 |
Ref: Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis. PMID: 15067322 Ref: Overexpression of regucalcin suppresses cell death in cloned rat hepatoma H4-II-E cells induced by tumor necrosis factor-alpha or thapsigargin. PMID: 15108356 Ref: Functional expression of TWEAK in human hepatocellular carcinoma: possible implication in cell proliferation and tumor angiogenesis. PMID: 15144899 Ref: Alpha-fetoprotein impairs APC function and induces their apoptosis. PMID: 15265907 Ref: Increased risk of developing hepatocellular carcinoma associated with carriage of the TNF2 allele of the -308 tumor necrosis factor-alpha promoter gene. PMID: 15280623 Ref: Glutamate-cysteine ligase attenuates TNF-induced mitochondrial injury and apoptosis. PMID: 15288121 Ref: Ethanol increases tumor necrosis factor-alpha receptor-1 (TNF-R1) levels in hepatic, intestinal, and cardiac cells. PMID: 15353169 Ref: Up-regulation of the high-affinity pyrimidine-preferring nucleoside transporter concentrative nucleoside transporter 1 by tumor necrosis factor-alpha and interleukin-6 in liver parenchymal cells. PMID: 15464233 |
Ref: Down-regulation of aryl hydrocarbon receptor-regulated genes by tumor necrosis factor-alpha and lipopolysaccharide in murine hepatoma Hepa 1c1c7 cells. PMID: 15627257 Ref: Molecular profiling of early stage liver fibrosis in patients with chronic hepatitis C virus infection. PMID: 15661146 Ref: Modulation of apoptosis as a target for liver disease. PMID: 15757484 Ref: Enhancement of leukocyte adhesion after percutaneous irradiation in rats with hepatocellular carcinoma. PMID: 15800992 Ref: [Anticarcinogenic effect of 20(R)-ginsenoside Rg3 on induced hepatocellular carcinoma in rats]. PMID: 15807271 Ref: IKKbeta phosphorylates p65 at S468 in transactivaton domain 2. PMID: 16046471 Ref: Cancer cachexia results in an increase in TNF-alpha receptor gene expression in both skeletal muscle and adipose tissue. PMID: 16077938 Ref: Kupffer cell-expressed membrane-bound TNF mediates melphalan hepatotoxicity via activation of both TNF receptors. PMID: 16148157 Ref: Synergistic effect of bromocriptine and tumor necrosis factor-alpha on reversing hepatocellular carcinoma multidrug resistance in nude mouse MDR1 model of liver neoplasm. PMID: 16237754 Ref: [Synergistic effect of bromocriptine combining tumor necrosis factor-alpha on reversing multidrug resistance in a nude mouse model of liver neoplasm]. PMID: 16271222 Ref: Tumor necrosis factor gene polymorphisms and clearance or progression of hepatitis B virus infection. PMID: 16343069 Ref: Augmentation of tumor necrosis factor family-induced apoptosis by E3330 in human hepatocellular carcinoma cell lines via inhibition of NF kappa B. PMID: 16419152 Ref: Cytokine profile in Egyptian hepatitis C virus genotype-4 in relation to liver disease progression. PMID: 16425355 |
Ref: Safety limit of large-volume hepatic radiofrequency ablation in a rat model. PMID: 16549690 Ref: Anti-inflammatory effect of pitavastatin on NF-kappaB activated by TNF-alpha in hepatocellular carcinoma cells. PMID: 16595893 Ref: COX-2 inhibitors sensitize human hepatocellular carcinoma cells to TRAIL-induced apoptosis. PMID: 16786154 Ref: Clinical monitoring of innate cellular immunity of monocytes/macrophages by tumor necrosis factor alpha productivity in whole blood stimulated by lipopolysaccharide in patients with pancreatic cancer. PMID: 16804410 Ref: The cyclin-dependent kinase inhibitor flavopiridol sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis. PMID: 16820931 Ref: Evaluation of tumour necrosis factor-alpha, soluble P-selectin, gamma-glutamyl transferase, glutathione S-transferase-pi and alpha-fetoprotein in patients with hepatocellular carcinoma before and during chemotherapy. PMID: 16871999 Ref: Cachexia--induced cerebellar degeneration: involvement of serum TNF and MCP-1 in the course of experimental neoplastic disease. PMID: 16886721 Ref: Different protection mechanisms after pretreatment with glycine or alpha-lipoic acid in a rat model of warm hepatic ischemia. PMID: 17028433 Ref: The levels of ghrelin, leptin, TNF-alpha, and IL-6 in liver cirrhosis and hepatocellular carcinoma due to HBV and HDV infection. PMID: 17047295 Ref: [Study on sensitivity to chemotherapy by combination therapy with tumor necrosis factor-alpha and bromocriptine in the multidrug resistant subcell line of HepG2]. PMID: 17359700 |
Ref: Unmasking of alpha-fetoprotein-specific CD4(+) T cell responses in hepatocellular carcinoma patients undergoing embolization. PMID: 17237442 Ref: Gene expression pattern in apoptotic QGY-7703 cells induced by homoharringtonine. PMID: 17506945 Ref: Nutritional treatment of cancer cachexia in rats. Use of a diet formulated with a crayfish enzymatic extract. PMID: 17676424 Ref: Tumor necrosis factor-alpha 308.2 polymorphism is associated with advanced hepatic fibrosis and higher risk for hepatocellular carcinoma. PMID: 18030367 Ref: Association of HLA-DRB1*13 and TNF-alpha gene polymorphisms with clearance of chronic hepatitis B infection and risk of hepatocellular carcinoma in Thai population. PMID: 18070287 |
Ref: Tumor necrosis factor-like weak inducer of apoptosis attenuates the action of insulin in hepatocytes. PMID: 18174283 Ref: Suppression of FasL expression in tumor cells and preventing TNF-induced apoptosis was better for immune cells survival. PMID: 18461366 Ref: TNF: a moonlighting protein at the interface between cancer and infection. PMID: 18508593 Ref: Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon. PMID: 18574467 Ref: Interaction between interleukin-1beta -31T/C gene polymorphism and drinking and smoking habits on the risk of hepatocellular carcinoma among Japanese. PMID: 18603357 Ref: Genetic profile of Egyptian hepatocellular-carcinoma associated with hepatitis C virus Genotype 4 by 15 K cDNA microarray: preliminary study. PMID: 18959789 Ref: Innate immune reactivity of the liver in rats fed a choline-deficient L-amino-acid-defined diet. PMID: 19034968 Ref: Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats. PMID: 19061005 |
Ref: Down-regulation of the de-ubiquitinating enzyme ubiquitin-specific protease 2 contributes to tumor necrosis factor-alpha-induced hepatocyte survival. PMID: 19001362 Ref: Expression of pro- and anti-inflammatory cytokines in relation to apoptotic genes in Egyptian liver disease patients associated with HCV-genotype-4. PMID: 19054267 Ref: Reduction of liver tumor necrosis factor-alpha expression by targeting delivery of antisense oligonucleotides into Kupffer cells protects rats from fulminant hepatitis. PMID: 19189285 Ref: TNF-based isolated hepatic perfusion. PMID: 19273161 Ref: Inhibition of UV-C light-induced apoptosis in liver cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin. PMID: 19520675 Ref: [Analysis of differential gene expression in rat hepatic stellate cells activated by culture or hepatocellular carcinoma cell induction]. PMID: 19615251 Ref: G-308A TNF-alpha polymorphism is associated with an increased risk of hepatocellular carcinoma in the Turkish population: case-control study. PMID: 19683483 Ref: [Diagnosis and therapy in NASH]. PMID: 19860210 Ref: Independent and additive interactive effects among tumor necrosis factor-alpha polymorphisms, substance use habits, and chronic hepatitis B and hepatitis C virus infection on risk for hepatocellular carcinoma. PMID: 19910749 |
Ref: Elevated serum tumor necrosis factor-alpha and soluble tumor necrosis factor receptors correlate with aberrant energy metabolism in liver cirrhosis. PMID: 19695831 Ref: Chemotherapy-induced apoptosis in hepatocellular carcinoma involves the p53 family and is mediated via the extrinsic and the intrinsic pathway. PMID: 19711344 Ref: Inflammatory tumour microenvironment is associated with superior survival in hepatocellular carcinoma patients. PMID: 19720422 Ref: Interaction of adipokines and hepatitis B virus on histological liver injury in the Chinese. PMID: 19809411 Ref: Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression. PMID: 20034026 Ref: Xanthohumol, a prenylated chalcone derived from hops, inhibits proliferation, migration and interleukin-8 expression of hepatocellular carcinoma cells. PMID: 20043079 Ref: Single nucleotide polymorphisms of 8 inflammation-related genes and their associations with smoking-related cancers. PMID: 20112337 Ref: Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. PMID: 20141834 Ref: Obesity, inflammatory signaling, and hepatocellular carcinoma-an enlarging link. PMID: 20159605 Ref: Soluble angiogenesis factors in sera of Egyptian patients with hepatitis C virus infection: correlation with disease severity. PMID: 20373995 Ref: DeltaNp73beta is oncogenic in hepatocellular carcinoma by blocking apoptosis signaling via death receptors and mitochondria. PMID: 20581467 Ref: Gastrin-releasing peptide promotes the growth of HepG2 cells via EGFR-independent ERK1/2 activation. PMID: 20596631 Ref: Effects of sulfur amino acids, L: -methionine, L: -cystine and L: -cysteine on lipoprotein lipase and hormone-sensitive lipase in differentiated mouse 3T3-L1 adipocytes. PMID: 20628900 Ref: Role of IL-6 activated STAT3 and TNF expression in obesity-associated hepatocellular carcinoma. PMID: 20636625 Ref: Malignant but not naive hepatocytes of human and rodent origin are killed by TNF after metabolic depletion of ATP by fructose. PMID: 20800309 Ref: Tumour necrosis factor-alpha polymorphisms and hepatocellular carcinoma: a meta-analysis. PMID: 20819413 Ref: An integrated genomic and epigenomic approach predicts therapeutic response to zebularine in human liver cancer. PMID: 20962331 Ref: Tumour necrosis factor 308 polymorphisms and hepatocellular carcinoma risk: a meta-analysis. PMID: 21033253 Ref: A study of TNF-alpha-238 and -308 polymorphisms with different outcomes of persistent hepatitis B virus infection in China. PMID: 21080879 Ref: Prognostic value of TNF a mRNA and VEGF mRNA expression in patients with chronic hepatitis C genotype-4, with and without cirrhosis and hepatocellular carcinoma to predict disease outcome. PMID: 21246958 |
Ref: Cellular inhibitor of apoptosis 1 (cIAP-1) degradation by caspase 8 during TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. PMID: 20951133 Ref: The TNF-alpha, IL-1B and IL-10 polymorphisms and risk for hepatocellular carcinoma: a meta-analysis. PMID: 21107607 Ref: Predictive value of serum biomarkers in patients after portal vein embolization (PVE): a pilot study. PMID: 21273621 Ref: Concomitant apoptosis and regeneration of liver cells as a mechanism of liver-tumor promotion by beta-naphthoflavone involving TNFalpha-signaling due to oxidative cellular stress in rats. PMID: 21295105 Ref: Association between single nucleotide polymorphisms in the cyclooxygenase-2, tumor necrosis factor-alpha, and vascular endothelial growth factor-A genes, and susceptibility to hepatocellular carcinoma. PMID: 21319995 Ref: Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation. PMID: 21327457 Ref: Polymorphisms of tumor necrosis factor-alpha and hepatocellular carcinoma risk: a HuGE systematic review and meta-analysis. PMID: 21336601 Ref: Tumor necrosis factor alpha 308 G/A polymorphism and hepatocellular carcinoma risk in a Chinese population. PMID: 21401328 Ref: Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF-alpha. PMID: 21421544 Ref: Use of three-dimensional spheroids of hepatocyte-derived reporter cells to study the effects of intracellular fat accumulation and subsequent cytokine exposure. PMID: 21449029 Ref: Targeting cell death and survival receptors in hepatocellular carcinoma. PMID: 21554206 Ref: Association of TNF-alpha genetic polymorphisms with hepatocellular carcinoma susceptibility: a case-control study in a Han Chinese population. PMID: 21928250 Ref: Antitumor immunity produced by the liver Kupffer cells, NK cells, NKT cells, and CD8 CD122 T cells. PMID: 22190974 |
Ref: Cytokines as important playmakers of experimental hepatocarcinogenesis confounded by diabetes. PMID: 22166570 Ref: Tumor necrosis factor-alpha -308G/A polymorphism and risk of hepatocellular carcinoma in hepatitis C virus-infected patients. PMID: 22200181 Ref: Production of bioactive, SUMO-modified, and native-like TNF-alpha of the rhesus monkey, Macaca mulatta, in Escherichia coli. PMID: 22207214 Ref: Association of a TANK gene polymorphism with outcomes of hepatitis B virus infection in a Chinese Han population. PMID: 22225470 Ref: Hepatitis C virus induced insulin resistance impairs response to anti viral therapy. PMID: 22294824 Ref: Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace. PMID: 22326465 Ref: Quercetin attenuates TNF-induced inflammation in hepatic cells by inhibiting the NF-kappaB pathway. PMID: 22452660 Ref: Growth inhibition and apoptosis induced by osthole, a natural coumarin, in hepatocellular carcinoma. PMID: 22662241 Ref: Influence of transforming growth factor-beta1 and tumor necrosis factor-alpha genes polymorphisms on the development of cirrhosis and hepatocellular carcinoma in chronic hepatitis C patients. PMID: 22682513 Ref: Association of TNF-alpha promoter polymorphisms with the outcome of persistent HBV infection in a northeast Chinese Han population. PMID: 22695741 Ref: The proinflammatory myeloid cell receptor TREM-1 controls Kupffer cell activation and development of hepatocellular carcinoma. PMID: 22719066 Ref: Pentoxifylline improves liver regeneration through down-regulation of TNF-alpha synthesis and TGF-beta1 gene expression. PMID: 22816029 Ref: Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. PMID: 22820288 Ref: Mitochondrial DNA maintenance is regulated in human hepatoma cells by glycogen synthase kinase 3beta and p53 in response to tumor necrosis factor alpha. PMID: 22911714 Ref: TNF-alpha -863 polymorphisms and the risk of hepatocellular carcinoma. PMID: 22969921 Ref: APRIL binding to BCMA activates a JNK2-FOXO3-GADD45 pathway and induces a G2/M cell growth arrest in liver cells. PMID: 23071284 Ref: [Analysis of the dynamic changes of blood hormone levels in H22 liver cancer mice of poisonous pathogenic factors syndromes to different degrees]. PMID: 23163147 Ref: Selective protection of human liver tissue in TNF-targeting of cancers of the liver by transient depletion of adenosine triphosphate. PMID: 23272249 Ref: Association between EGF, TGF-beta1 and TNF-alpha gene polymorphisms and hepatocellular carcinoma. PMID: 23464434 Ref: Apigenin Sensitizes Huh-7 Human Hepatocellular Carcinoma Cells to TRAIL-induced Apoptosis. PMID: 24116276 |
Ref: Genetic predisposition of hand-foot skin reaction after sorafenib therapy in patients with hepatocellular carcinoma. PMID: 22736425 Ref: Obesity and hepatocellular carcinoma: targeting obesity-related inflammation for chemoprevention of liver carcinogenesis. PMID: 22945457 Ref: Alleles and genotypes of polymorphisms of IL-18, TNF-alpha and IFN-gamma are associated with a higher risk and severity of hepatocellular carcinoma (HCC) in Brazil. PMID: 23632060 Ref: Bufalin induces G2/M phase arrest and triggers autophagy via the TNF, JNK, BECN-1 and ATG8 pathway in human hepatoma cells. PMID: 23677253 Ref: Measurement of transporter associated with antigen processing 1 and tumor necrosis factor alpha expression in hepatitis B virus-related hepatocellular carcinoma and peritumor cirrhosis tissues using tissue chip technology. PMID: 23682387 Ref: JNK activation is required for TNFalpha-induced apoptosis in human hepatocarcinoma cells. PMID: 23751896 Ref: Tumor necrosis factor-alpha 238 G/A polymorphism and risk of hepatocellular carcinoma: evidence from a meta-analysis. PMID: 23803115 Ref: Evaluation of potential reference genes for qRT-PCR studies in human hepatoma cell lines treated with TNF-alpha. PMID: 23811755 Ref: Diabetic liver injury from streptozotocin is regulated through the caspase-8 homolog cFLIP involving activation of JNK2 and intrahepatic immunocompetent cells. PMID: 23828575 Ref: Magnetic resonance imaging biomarkers in hepatocellular carcinoma: association with response and circulating biomarkers after sunitinib therapy. PMID: 23842041 Ref: TNFR1 determines progression of chronic liver injury in the IKKgamma/Nemo genetic model. PMID: 23933814 Ref: Inhibition of nuclear factor-kappaB enhances the antitumor effect of tumor necrosis factor-alpha gene therapy for hepatocellular carcinoma in mice. PMID: 23972653 Ref: TNF-alpha, HGF and macrophage in peritumoural liver tissue relate to major risk factors of HCC Recurrence. PMID: 24018067 Ref: A Possible Role for TNF-alpha in Coordinating Inflammation and Angiogenesis in Chronic Liver Disease and Hepatocellular Carcinoma. PMID: 24147158 Ref: iSubgraph: integrative genomics for subgroup discovery in hepatocellular carcinoma using graph mining and mixture models. PMID: 24223834 Ref: Human tumor necrosis factor (TNF)-alpha-induced protein 8-like 2 suppresses hepatocellular carcinoma metastasis through inhibiting Rac1. PMID: 24274578 Ref: The Inhibitory Effect of 3 beta -Hydroxy-12-oleanen-27-oic Acid on Growth and Motility of Human Hepatoma HepG2 Cells through JNK and Akt Signaling Pathway. PMID: 24379889 Ref: TNF-alpha-308 polymorphism and risk of digestive system cancers: a meta-analysis. PMID: 24409077 |
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