Primary Site >> Colorectal Cancer
Gene >> TMPRSS4
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Ref: TMPRSS4 promotes invasion, migration and metastasis of human tumor cells by facilitating an epithelial-mesenchymal transition. PMID: 17968309 Ref: IL-4/Stat6 activities correlate with apoptosis and metastasis in colon cancer cells. PMID: 18294957 |
Ref: TMPRSS4 induces invasion and epithelial-mesenchymal transition through upregulation of integrin alpha5 and its signaling pathways. PMID: 20118200 |
Ref: Discovery of novel 2-hydroxydiarylamide derivatives as TMPRSS4 inhibitors. PMID: 23414802 Ref: High expression level of TMPRSS4 predicts adverse outcomes of colorectal cancer patients. PMID: 24072509 |
Ref: TMPRSS4 correlates with colorectal cancer pathological stage and regulates cell proliferation and self-renewal ability. PMID: 24335200 Ref: TMPRSS4 induces cancer cell invasion through pro-uPA processing. PMID: 24434139 |