Primary Site >> Colorectal Cancer
Gene >> TMEFF2
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Ref: The gene for a novel transmembrane protein containing epidermal growth factor and follistatin domains is frequently hypermethylated in human tumor cells. PMID: 10987305 Ref: Hyperplastic polyps and DNA microsatellite unstable cancers of the colorectum. PMID: 11012735 |
Ref: HPP1: a transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancers. PMID: 11120884 |
Ref: Aberrant methylation of the HPP1 gene in ulcerative colitis-associated colorectal carcinoma. PMID: 12460892 Ref: Mutation searching in colorectal cancer studies: experience with a denaturing high-pressure liquid chromatography system for exon-by-exon scanning of tumour suppressor genes. PMID: 12555990 |
Ref: Multigene methylation analysis of gastrointestinal tumors: TPEF emerges as a frequent tumor-specific aberrantly methylated marker that can be detected in peripheral blood. PMID: 15068392 |
Ref: Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer. PMID: 15016754 Ref: Promoter hypermethylation frequency and BRAF mutations distinguish hereditary non-polyposis colon cancer from sporadic MSI-H colon cancer. PMID: 15340260 Ref: Use of DNA from human stools to detect aberrant CpG island methylation of genes implicated in colorectal cancer. PMID: 15342451 |
Ref: Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers. PMID: 16207479 |
Ref: DNA methylation patterns in adenomas from FAP, multiple adenoma and sporadic colorectal carcinoma patients. PMID: 16152625 Ref: Methylation of serum DNA is an independent prognostic marker in colorectal cancer. PMID: 17189406 |
Ref: Detection of aberrant methylation in fecal DNA as a molecular screening tool for colorectal cancer and precancerous lesions. PMID: 17352030 Ref: Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasias. PMID: 17408633 |
Ref: HPP1-mediated tumor suppression requires activation of STAT1 pathways. PMID: 18059030 Ref: DNA methylation biomarkers for blood-based colorectal cancer screening. PMID: 18089654 Ref: Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa. PMID: 18542073 |
Ref: Methylation of helicase-like transcription factor in serum of patients with colorectal cancer is an independent predictor of disease recurrence. PMID: 19282772 |
Ref: Aberrant gene promoter methylation associated with sporadic multiple colorectal cancer. PMID: 20098741 Ref: Methylation status of genes in non-neoplastic mucosa from patients with ulcerative colitis-associated colorectal cancer. PMID: 20160714 Ref: A combined HM-PCR/SNuPE method for high sensitive detection of rare DNA methylation. PMID: 20525169 Ref: Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas. PMID: 20572039 Ref: Development of a multiplex MethyLight assay for the detection of multigene methylation in human colorectal cancer. PMID: 20804913 Ref: DNA methylation in patients with colorectal cancer--correlation with some clinical and morphological features and with local tumour invasion. PMID: 20836393 |
Ref: Methylation of NEUROG1 in serum is a sensitive marker for the detection of early colorectal cancer. PMID: 21326223 Ref: DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis. PMID: 22132162 |
Ref: [Multi-gene methylation detection increases positive methylation rate in colorectal cancer]. PMID: 22736139 |
Ref: Novel methylation panel for the early detection of neoplasia in high-risk ulcerative colitis and Crohn's colitis patients. PMID: 22532293 Ref: Label-free imaging characteristics of colonic mucinous adenocarcinoma using multiphoton microscopy. PMID: 23168617 |
Ref: A panel of genes methylated with high frequency in colorectal cancer. PMID: 24485021 Ref: The interplay between histone deacetylases and c-Myc in the transcriptional suppression of HPP1 in colon cancer. PMID: 24919179 |
Ref: The identification of specific methylation patterns across different cancers. PMID: 25774687 Ref: Multiphoton microscopy for tumor regression grading after neoadjuvant treatment for colorectal carcinoma. PMID: 25892870 Ref: The Tumor Suppressive Effects of HPP1 Are Mediated Through JAK-STAT-Interferon Signaling Pathways. PMID: 26061044 Ref: Comprehensive DNA Methylation Analysis Reveals a Common Ten-Gene Methylation Signature in Colorectal Adenomas and Carcinomas. PMID: 26291085 Ref: Phytochemical Indicaxanthin Inhibits Colon Cancer Cell Growth and Affects the DNA Methylation Status by Influencing Epigenetically Modifying Enzyme Expression and Activity. PMID: 26439130 |
Ref: Hypermethylated DNA as a biomarker for colorectal cancer: a systematic review. PMID: 26998585 Ref: DNA methylation based biomarkers in colorectal cancer: A systematic review. PMID: 27385266 |
Ref: Identification of differentially expressed genes and their upstream regulators in colorectal cancer. PMID: 28409560 |