Primary Site >> Colorectal Cancer

Gene >> TLR7

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Ref: An oral TLR7 agonist is a potent adjuvant of DNA vaccination in transgenic mouse tumor models.
PMID: 18989354
Ref: Autophagy-mediated anti-tumoral activity of imiquimod in Caco-2 cells.
PMID: 19527683
Ref: Toll-like receptors and the tendency of normal mucous membrane to transform to polyp or colorectal cancer.
PMID: 19609015
Ref: Antitumor activity and immune response induction of a dual agonist of Toll-like receptors 7 and 8.
PMID: 20515950
Ref: Potentiation of the anti-tumor effects of imidazoquinoline immune response modifiers by cyclophosphamide.
PMID: 20519933
Ref: Toll-like receptor (TLR) 7 and TLR8 expression on CD133+ cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression.
PMID: 20728343
Ref: Inhibition and promotion of tumor growth with adeno-associated virus carcinoembryonic antigen vaccine and Toll-like receptor agonists.
PMID: 21869824
Ref: Study of the expression of toll-like receptors in different histological types of colorectal polyps and their relationship with colorectal cancer.
PMID: 22371291
Ref: Synergistical toll-like receptors activated dendritic cells induce antitumor effects against carcinoembryonic antigen-expressing colon cancer.
PMID: 22777000
Ref: Toll-like receptor-4 expression by stromal fibroblasts is associated with poor prognosis in colorectal cancer.
PMID: 23799413
Ref: A novel systemically administered Toll-like receptor 7 agonist potentiates the effect of ionizing radiation in murine solid tumor models.
PMID: 24390981
Ref: TLR7 ligand augments GM-CSF-initiated antitumor immunity through activation of plasmacytoid dendritic cells.
PMID: 24830413
Ref: Intervention on toll-like receptors in pancreatic cancer.
PMID: 24914341
Ref: The TLR7 agonist induces tumor regression both by promoting CD4(+)T cells proliferation and by reversing T regulatory cell-mediated suppression via dendritic cells.
PMID: 25593198
Ref: Intravenous administration of the selective toll-like receptor 7 agonist DSR-29133 leads to anti-tumor efficacy in murine solid tumor models which can be potentiated by combination with fractionated radiotherapy.
PMID: 26959743
Ref: Antitumor Activity of TLR7 Is Potentiated by CD200R Antibody Leading to Changes in the Tumor Microenvironment.
PMID: 30021725
Ref: Colorectal Cancer-derived Small Extracellular Vesicles Establish an Inflammatory Pre-metastatic Niche in Liver Metastasis.
PMID: 30184100