Primary Site >> Stomach Cancer
Gene >> TLR4
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Ref: Cancer registry in New Zealand. PMID: 613245 |
Ref: Epidemiological factors of cancer in California. PMID: 1464811 |
Ref: Distinct mechanism of Helicobacter pylori-mediated NF-kappa B activation between gastric cancer cells and monocytic cells. PMID: 11546774 |
Ref: Endotoxic and immunobiological activities of a chemically synthesized lipid A of Helicobacter pylori strain 206-1. PMID: 12727359 |
Ref: Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice. PMID: 15014433 Ref: Essential role of MD-2 in TLR4-dependent signaling during Helicobacter pylori-associated gastritis. PMID: 15240737 Ref: Induction of cyclooxygenase-2 overexpression in human gastric epithelial cells by Helicobacter pylori involves TLR2/TLR9 and c-Src-dependent nuclear factor-kappaB activation. PMID: 15456896 Ref: [Experimental study for a combination chemo-immunotherapy using dendritic cells]. PMID: 15553666 |
Ref: Toll-like receptors TLR4, TLR5 and TLR9 on gastric carcinoma cells: an implication for interaction with Helicobacter pylori. PMID: 16044857 Ref: Sex differences in cytokine production and surface antigen expression of peripheral blood mononuclear cells after surgery. PMID: 16105533 |
Ref: Heterozygous Thr 135 Ala polymorphism at leucine-rich repeat (LRR) in genomic DNA of toll-like receptor 4 in patients with poorly-differentiated gastric adenocarcinomas. PMID: 16786156 Ref: Human beta-defensin-3 induction in H. pylori-infected gastric mucosal tissues. PMID: 17007044 Ref: Essential requirement of toll-like receptor 4 expression on CD11c+ cells for locoregional immunotherapy of malignant ascites using a streptococcal preparation OK-432. PMID: 17094388 |
Ref: [What is the most important factor for gastric carcinogenesis in Koreans: Helicobacter pylori, host factor or environmental factor?]. PMID: 17322784 Ref: A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. PMID: 17324405 Ref: Assessment of the toll-like receptor 4 Asp299Gly, Thr399Ile and interleukin-8 -251 polymorphisms in the risk for the development of distal gastric cancer. PMID: 17462092 Ref: Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling. PMID: 17483348 Ref: Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer. PMID: 17568183 Ref: MD-2 as the target of curcumin in the inhibition of response to LPS. PMID: 17609337 Ref: Absence of Common Polymorphisms of Toll Like Receptor 4 (TLR4): Asp299Gly, Thr399Ile in Patients with Gastroduodenal Diseases in Japan. PMID: 18437214 Ref: Association of polymorphism of TLR4 and CD14 genes with gastroduodenal diseases in Japan. PMID: 19847953 |
Ref: TLR4 single-nucleotide polymorphisms alter mucosal cytokine and chemokine patterns in Mexican patients with Helicobacter pylori-associated gastroduodenal diseases. PMID: 18755634 Ref: Helicobacter pylori protein HP0175 transactivates epidermal growth factor receptor through TLR4 in gastric epithelial cells. PMID: 18806258 Ref: Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms in gastric cancer of intestinal and diffuse histotypes. PMID: 18826495 |
Ref: Toll-like receptor 4 +3725 G/C polymorphism, Helicobacter pylori seropositivity, and the risk of gastric atrophy and gastric cancer in Japanese. PMID: 19191896 Ref: Association of gastric disease with polymorphisms in the inflammatory-related genes IL-1B, IL-1RN, IL-10, TNF and TLR4. PMID: 19295440 Ref: CD14 promoter-159 polymorphism is associated with reduced risk of intestinal-type gastric cancer in a Japanese population. PMID: 19326213 |
Ref: Significant association between toll-like receptor gene polymorphisms and gallbladder cancer. PMID: 20492496 Ref: Genetic predisposition to Helicobacter pylori-induced gastric precancerous conditions. PMID: 21160888 Ref: A 5'-flanking region polymorphism in toll-like receptor 4 is associated with gastric cancer in a Chinese population. PMID: 23554619 |
Ref: Combined effect of miR-146a rs2910164 G/C polymorphism and Toll-like receptor 4 +3725 G/C polymorphism on the risk of severe gastric atrophy in Japanese. PMID: 20721625 Ref: Impact of Toll-like receptor 4 polymorphisms on risk of cancer. PMID: 21081146 Ref: Neutrophils promote motility of cancer cells via a hyaluronan-mediated TLR4/PI3K activation loop. PMID: 21826665 |
Ref: Polymorphisms of the TLR2 and TLR4 genes are associated with risk of gastric cancer in a Brazilian population. PMID: 22468087 Ref: Impaired dendritic cell maturation and IL-10 production following H. pylori stimulation in gastric cancer patients. PMID: 22526791 Ref: CD74 and macrophage migration inhibitory factor as therapeutic targets in gastric cancer. PMID: 22611320 |
Ref: The TLR4 gene polymorphisms and susceptibility to cancer: a systematic review and meta-analysis. PMID: 23084080 Ref: Profiles of gene polymorphisms in cytokines and Toll-like receptors with higher risk for gastric cancer. PMID: 23086128 Ref: The role of TLR2, TLR4 and CD14 genetic polymorphisms in gastric carcinogenesis: a case-control study and meta-analysis. PMID: 23565226 Ref: Positive association between Toll-like receptor 4 gene +896A/G polymorphism and susceptibility to gastric carcinogenesis: a meta-analysis. PMID: 23592020 Ref: TLR9 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis. PMID: 23776537 Ref: Toll-like receptors and cytokines are upregulated during Helicobacter pylori infection in children. PMID: 23869400 Ref: CD14 regulates gastric cancer cell epithelialmesenchymal transition and invasion in vitro. PMID: 24064911 Ref: Effects of polymorphisms of innate immunity genes and environmental factors on the risk of noncardia gastric cancer. PMID: 24454004 |
Ref: Differential role of MyD88 and Mal/TIRAP in TLR2-mediated gastric tumourigenesis. PMID: 23728346 Ref: Polymorphisms of Helicobacter pylori signaling pathway genes and gastric cancer risk in the European Prospective Investigation into Cancer-Eurgast cohort. PMID: 23824692 Ref: Host genetic factors respond to pathogenic step-specific virulence factors of Helicobacter pylori in gastric carcinogenesis. PMID: 24076409 Ref: TLR4 polymorphisms associated with developing gastric pre-cancer lesions in a Chinese Han population. PMID: 24269697 Ref: Study of TLR4 and IL-8 gene polymorphisms in H.pylori-induced inflammation in gastric cancer in an ethnic Kashmiri population. PMID: 24295404 Ref: Polymorphisms of the TLR4 gene and risk of gastric cancer. PMID: 24365597 Ref: The mannose-sensitive hemagglutination pilus strain of Pseudomonas aeruginosa shift peritoneal milky spot macrophages towards an M1 phenotype to dampen peritoneal dissemination. PMID: 24385384 Ref: Correlation between genetic polymorphisms within IL-1B and TLR4 genes and cancer risk in a Russian population: a case-control study. PMID: 24446182 Ref: Clinical significance of toll-like receptor 3, 4, and 9 in gastric cancer. PMID: 24509170 Ref: Novel role of toll-like receptors in Helicobacter pylori - induced gastric malignancy. PMID: 24833854 Ref: Genetic polymorphisms in the Toll-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer. PMID: 24929142 Ref: Resistin-induced stromal cell-derived factor-1 expression through Toll-like receptor 4 and activation of p38 MAPK/ NFkappaB signaling pathway in gastric cancer cells. PMID: 24929539 Ref: High Mobility Group Box1 (HMGB1) released from cancer cells induces the expression of pro-inflammatory cytokines in peritoneal fibroblasts. PMID: 24965109 Ref: Effect of the -2081G/A polymorphism of the TLR4 gene and its interaction with Helicobacter pylori infection on the risk of gastric cancer in Chinese individuals. PMID: 25084512 Ref: Uncontrolled inflammation induced by AEG-1 promotes gastric cancer and poor prognosis. PMID: 25092897 Ref: Pattern-recognition receptors and gastric cancer. PMID: 25101079 Ref: Mycoplasma hyorhinis induces epithelial-mesenchymal transition in gastric cancer cell MGC803 via TLR4-NF-kappaB signaling. PMID: 25149064 Ref: Association between TLR4 (+896A/G and +1196C/T) polymorphisms and gastric cancer risk: an updated meta-analysis. PMID: 25290654 Ref: Astragalus mongholicus regulate the Toll-like-receptor 4 meditated signal transduction of dendritic cells to restrain stomach cancer cells. PMID: 25371568 Ref: Helicobacter pylori regulates TLR4 and TLR9 during gastric carcinogenesis. PMID: 25400780 |
Ref: Toll-like receptor gene polymorphisms and susceptibility to Epstein-Barr virus-associated and -negative gastric carcinoma in Northern China. PMID: 25843196 Ref: SNP interactions of Helicobacter pylori-related host genes PGC, PTPN11, IL1B, and TLR4 in susceptibility to gastric carcinogenesis. PMID: 26158864 Ref: Toll-Like Receptor 4 Wild Type Homozygozity of Polymorphisms +896 and +1196 Is Associated with High Gastrin Serum Levels and Peptic Ulcer Risk. PMID: 26161647 Ref: The influence of cytokine gene polymorphisms on the risk of developing gastric cancer in patients with Helicobacter pylori infection. PMID: 26401131 Ref: The function of miR-199a-5p/Klotho regulating TLR4/NF-kappaB p65/NGAL pathways in rat mesangial cells cultured with high glucose and the mechanism. PMID: 26419931 Ref: [Effect of Toll-like receptor 4 signaling activation on the biological behavior of gastric cancer cell lines]. PMID: 26710875 Ref: Pooled analysis of association between a genetic variant in the 3'-untranslated region of Toll-like receptor 4 and cancer risk. PMID: 26782430 |
Ref: Epigenetic modification of TLR4 promotes activation of NF-kappaB by regulating methyl-CpG-binding domain protein 2 and Sp1 in gastric cancer. PMID: 26675260 Ref: Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therapy Using the Bifidobacterium-Mediated Recombinant HSV-1 Thymidine Kinase and Ganciclovir. PMID: 27275821 Ref: Biglycan stimulates VEGF expression in endothelial cells by activating the TLR signaling pathway. PMID: 27590684 Ref: Importance of the C-terminal histidine residues of Helicobacter pylori GroES for Toll-like receptor 4 binding and interleukin-8 cytokine production. PMID: 27869178 |
Ref: Genetic variants of TLR4 and TLR9 are risk factors for chronic Helicobacter pylori infection in South Indian Tamils. PMID: 27993530 Ref: Antioxidant, antitumor and immunostimulatory activities of the polypeptide from Pleurotus eryngii mycelium. PMID: 28093329 Ref: Dysregulation of mRNA profile in cisplatin-resistant gastric cancer cell line SGC7901. PMID: 28275299 Ref: High mobility group box 1/toll-like receptor 4/myeloid differentiation factor 88 signaling promotes progression of gastric cancer. PMID: 28347236 Ref: Host Determinants of Expression of the Helicobacter pylori BabA Adhesin. PMID: 28418004 Ref: Low-dose paclitaxel suppresses the induction of M2 macrophages in gastric cancer. PMID: 28440494 Ref: KDM3A promotes inhibitory cytokines secretion by participating in TLR4 regulation of Foxp3 transcription in lung adenocarcinoma cells. PMID: 28521455 |
Ref: Polyene phosphatidylcholine overcomes oxaliplatin resistance in human gastric cancer BGC823 cells. PMID: 29421658 Ref: miR-198 regulated the tumorigenesis of gastric cancer by targeting Toll-like receptor 4 (TLR4). PMID: 29762851 Ref: Induction of Pro-Inflammatory Response via Activated Macrophage-Mediated NF-kappaB and STAT3 Pathways in Gastric Cancer Cells. PMID: 29929193 Ref: Toll-like receptors TLR-2, TLR-4, TLR-7, and TLR-9 in tumor tissue and serum of the patients with esophageal squamous cell carcinoma and gastro-esophageal junction cancer. PMID: 29968427 Ref: Leading causes of death of women of reproductive age in the Republic of Georgia: findings from the National Reproductive Age Mortality Survey (2014). PMID: 30147381 Ref: Minor allele of rs1057317 polymorphism in TLR4 is associated with increased risk of Helicobacter pylori -induced gastric cancer. PMID: 30242897 Ref: Tumor-derived exosomes induce N2 polarization of neutrophils to promote gastric cancer cell migration. PMID: 30292233 Ref: Toll-like receptor 2 and 4 polymorphisms associated with Helicobacter pylori susceptibility and gastric cancer. PMID: 30301709 |