Primary Site >> Biliary tract Cancer

Gene >> TLR4

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Ref: Epidemiological factors of cancer in California.
PMID: 1464811
Ref: Lipopolysaccharide activates nuclear factor-kappaB through toll-like receptors and related molecules in cultured biliary epithelial cells.
PMID: 14615419
Ref: Opisthorchis viverrini antigen induces the expression of Toll-like receptor 2 in macrophage RAW cell line.
PMID: 15862573
Ref: Significant association between toll-like receptor gene polymorphisms and gallbladder cancer.
PMID: 20492496
Ref: Opisthorchis viverrini excretory/secretory products induce toll-like receptor 4 upregulation and production of interleukin 6 and 8 in cholangiocyte.
PMID: 20887801
Ref: Impact of Toll-like receptor 4 polymorphisms on risk of cancer.
PMID: 21081146
Ref: Gallbladder cancer predisposition: a multigenic approach to DNA-repair, apoptotic and inflammatory pathway genes.
PMID: 21283657
Ref: TLR4 expression in normal gallbladder, chronic cholecystitis and gallbladder carcinoma.
PMID: 22251522
Ref: Induction of cancer-related microRNA expression profiling using excretory-secretory products of Clonorchis sinensis.
PMID: 25217977
Ref: TLR4, TLR9, and NLRP3 in biliary epithelial cells of primary sclerosing cholangitis: relationship with clinical characteristics.
PMID: 25160604