Primary Site >> Colorectal Cancer
Gene >> TIAM1
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Ref: Tiam1 gene expression and its significance in colorectal carcinoma. PMID: 15655826 Ref: The guanine nucleotide exchange factor Tiam1 increases colon carcinoma growth at metastatic sites in an orthotopic nude mouse model. PMID: 15735692 Ref: [Tiam1 expression correlates with the biological behavior of human colorectal carcinoma cells]. PMID: 16536281 |
Ref: The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development. PMID: 16249175 Ref: Molecular detection of circulating cancer cells in the peripheral blood of patients with colorectal cancer by using membrane array with a multiple mRNA marker panel. PMID: 16391796 Ref: Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells. PMID: 17086355 Ref: Lentivirus-mediated silencing of Tiam1 gene influences multiple functions of a human colorectal cancer cell line. PMID: 17132223 |
Ref: Proteomic analysis of Tiam1-mediated metastasis in colorectal cancer. PMID: 17376711 Ref: [Effect of Tiam-l gene silencing on human colorectal carcinoma cell line SW480 metastasis in nude mice observed by real-time whole-body fluorescence imaging]. PMID: 17584632 |
Ref: Identification of potential genes/proteins regulated by Tiam1 in colorectal cancer by microarray analysis and proteome analysis. PMID: 18675922 Ref: Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells. PMID: 18826597 |
Ref: [Correlation between T lymphoma invasion and metastasis 1 expression and epithelial-mesenchymal transition in human colorectal carcinomas]. PMID: 19246286 Ref: Expression of Tiam1 and VEGF-C correlates with lymphangiogenesis in human colorectal carcinoma. PMID: 19276682 |
Ref: Syndecan-2 regulates cell migration in colon cancer cells through Tiam1-mediated Rac activation. PMID: 19962968 Ref: PTHrP promotes colon cancer cell migration and invasion in an integrin alpha6beta4-dependent manner through activation of Rac1. PMID: 20637541 Ref: miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells. PMID: 20826792 |
Ref: miRNA-22 suppresses colon cancer cell migration and invasion by inhibiting the expression of T-cell lymphoma invasion and metastasis 1 and matrix metalloproteinases 2 and 9. PMID: 23440286 Ref: Tiam1 transgenic mice display increased tumor invasive and metastatic potential of colorectal cancer after 1,2-dimethylhydrazine treatment. PMID: 24069171 |
Ref: miR-29b suppresses tumor growth and metastasis in colorectal cancer via downregulating Tiam1 expression and inhibiting epithelial-mesenchymal transition. PMID: 25032858 |
Ref: An EGFR/PI3K/AKT axis promotes accumulation of the Rac1-GEF Tiam1 that is critical in EGFR-driven tumorigenesis. PMID: 25746002 Ref: Down-regualtion of miR-106b induces epithelial-mesenchymal transition but suppresses metastatic colonization by targeting Prrx1 in colorectal cancer. PMID: 26617763 |
Ref: The predicted target gene validation, function, and prognosis studies of miRNA-22 in colorectal cancer tissue. PMID: 28347238 Ref: TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells. PMID: 28416184 Ref: A TIAM Double Hit to Oppose YAP/TAZ. PMID: 28486099 Ref: Inhibition of cell migration and invasion by miR29a3p in a colorectal cancer cell line through suppression of CDC42BPA mRNA expression. PMID: 29039592 Ref: TIAM1 inhibits lung fibroblast differentiation in pulmonary fibrosis. PMID: 29067109 |
Ref: Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis. PMID: 29920278 Ref: The CircRNA-ACAP2/Hsa-miR-21-5p/ Tiam1 Regulatory Feedback Circuit Affects the Proliferation, Migration, and Invasion of Colon Cancer SW480 Cells. PMID: 30212824 |