Primary Site >> Colorectal Cancer
Gene >> THBS1
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Ref: Association between CpG island methylation and microsatellite instability in colorectal cancer. PMID: 9269998 |
Ref: Alterations in tumour suppressor gene p53 correlate with inhibition of thrombospondin-1 gene expression in colon cancer cells. PMID: 9849855 Ref: Aging and DNA methylation in colorectal mucosa and cancer. PMID: 9850084 |
Ref: Expression of the thrombospondin 1 receptor CD36 is correlated with decreased stromal vascularisation in colon cancer. PMID: 9863008 Ref: Thrombospondin 2 expression is correlated with inhibition of angiogenesis and metastasis of colon cancer. PMID: 9888480 Ref: CpG island methylator phenotype in colorectal cancer. PMID: 10411935 Ref: Expression of angiostatic factors in colorectal cancer. PMID: 10568831 |
Ref: Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype. PMID: 10639144 Ref: A distinct tumor suppressor gene locus on chromosome 15q21.1 in sporadic form of colorectal cancer. PMID: 10646855 Ref: Expression of vascular endothelial growth factor and thrombospondin-1 in colorectal carcinoma. PMID: 10719053 Ref: Ribozyme-mediated inactivation of mutant K-ras oncogene in a colon cancer cell line. PMID: 10952790 Ref: Thrombospondin in colorectal disease. PMID: 23578039 |
Ref: Interleukin 10 expression is correlated with thrombospondin expression and decreased vascular involvement in colon cancer. PMID: 11179476 Ref: The localization of thrombospondin-1 (TSP-1), cysteine-serine-valine-threonine-cysteine-glycine (CSVTCG) TSP receptor, and matrix metalloproteinase-9 (MMP-9) in colorectal cancer. PMID: 11332689 Ref: Expression of thrombospondin-1 inversely correlated with tumor vascularity and hematogenous metastasis in colon cancer. PMID: 11410779 Ref: CpG island methylation in colorectal adenomas. PMID: 11549606 |
Ref: Expression and role of thrombospondin-1 in colorectal cancer. PMID: 12553016 |
Ref: Molecular targeting and pharmacogenomics in the management of advanced bladder cancer. PMID: 12673700 Ref: Defective processing of the transforming growth factor-beta1 in azoxymethane-induced mouse colon tumors. PMID: 12720300 Ref: BNF-1, a novel gene encoding a putative extracellular matrix protein, is overexpressed in tumor tissues. PMID: 12853144 Ref: Clinical significance of thrombospondin-1 expression in relation to vascular endothelial growth factor and interleukin-10 expression at the deepest invasive tumor site of advanced colorectal carcinoma. PMID: 12963968 |
Ref: Thrombospondin-1 plus irinotecan: a novel antiangiogenic-chemotherapeutic combination that inhibits the growth of advanced human colon tumor xenografts in mice. PMID: 14658007 Ref: Aberrant CpG island hypermethylation of multiple genes in colorectal neoplasia. PMID: 15122305 |
Ref: Progressive methylation during the serrated neoplasia pathway of the colorectum. PMID: 15389252 Ref: 1alpha,25-Dihydroxyvitamin D3 regulates the expression of Id1 and Id2 genes and the angiogenic phenotype of human colon carcinoma cells. PMID: 16007183 Ref: Aberrant CpG island methylation in early-onset sporadic gastric carcinoma. PMID: 16075282 Ref: Wnt signaling can repress thrombospondin-1 expression in colonic tumorigenesis. PMID: 16258261 Ref: CpG island methylation as an early event during adenoma progression in carcinogenesis of sporadic colorectal cancer. PMID: 16336454 |
Ref: CpG island methylation of genes accumulates during the adenoma progression step of the multistep pathogenesis of colorectal cancer. PMID: 16708352 Ref: The relationship between MSI status and vessel density in colorectal carcinoma. PMID: 16739879 |
Ref: Association of angiogenesis markers with lymph node metastasis in early colorectal cancer. PMID: 17709727 |
Ref: A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients. PMID: 18362940 Ref: Neoadjuvant treatment of colorectal cancer with bevacizumab: the perioperative angiogenic balance is sensitive to systemic thrombospondin-1 levels. PMID: 18381946 Ref: Anti-angiogenic effect of 5-Fluorouracil-based drugs against human colon cancer xenografts. PMID: 18420342 Ref: The aberrant methylation of TSP1 suppresses TGF-beta1 activation in colorectal cancer. PMID: 18425817 Ref: Antiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib. PMID: 18443598 Ref: Down regulation of c-Myc and induction of an angiogenesis inhibitor, thrombospondin-1, by 5-FU in human colon cancer KM12C cells. PMID: 18583030 Ref: Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families. PMID: 18619730 Ref: Molecular basis for the induction of an angiogenesis inhibitor, thrombospondin-1, by 5-fluorouracil. PMID: 18757417 |
Ref: Low-dose metronomic chemotherapy of paclitaxel synergizes with cetuximab to suppress human colon cancer xenografts. PMID: 19318912 Ref: Targeting both HIF-1 and HIF-2 in human colon cancer cells improves tumor response to sunitinib treatment. PMID: 19435875 Ref: [Study on radiation sensitivity of colorectal cancer cells using gene expression profile]. PMID: 19598022 |
Ref: Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression. PMID: 19998449 Ref: Variable inhibition of thrombospondin 1 against liver and lung metastases through differential activation of metalloproteinase ADAMTS1. PMID: 20103648 Ref: Identification of predictive markers of response to the MEK1/2 inhibitor selumetinib (AZD6244) in K-ras-mutated colorectal cancer. PMID: 20923857 |
Ref: DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis. PMID: 22132162 |
Ref: Thrombospondin-1 and VEGF in inflammatory bowel disease. PMID: 22299021 Ref: VEGF, PF4 and PDGF are elevated in platelets of colorectal cancer patients. PMID: 22402885 |
Ref: Thrombospondin-1 and pigment epithelium-derived factor enhance responsiveness of KM12 colon tumor to metronomic cyclophosphamide but have disparate effects on tumor metastasis. PMID: 23228633 Ref: Effects of anti-miR-182 on TSP-1 expression in human colon cancer cells: there is a sense in antisense? PMID: 24053448 |
Ref: Impact of Phytolacca americana extracts on gene expression of colon cancer cells. PMID: 23553997 Ref: BMP4/Thrombospondin-1 loop paracrinically inhibits tumor angiogenesis and suppresses the growth of solid tumors. PMID: 24013228 Ref: Mechanisms of platelet-stimulated colon cancer invasion: role of clusterin and thrombospondin 1 in regulation of the P38MAPK-MMP-9 pathway. PMID: 24085798 Ref: Pilot study of angiogenic response to yttrium-90 radioembolization with resin microspheres. PMID: 24360887 Ref: Masking epistasis between MYC and TGF-beta pathways in antiangiogenesis-mediated colon cancer suppression. PMID: 24627270 Ref: Anti-angiogenesis participates in antitumor effects of metronomic capecitabine on colon cancer. PMID: 24746899 Ref: Overexpression of the ITGAV gene is associated with progression and spread of colorectal cancer. PMID: 25275062 |
Ref: Gene expression differences in primary colorectal tumors and matched liver metastases: chemotherapy related or tumoral heterogeneity? PMID: 25301403 Ref: Surface profiles of live colorectal cancer cells and tumor infiltrating lymphocytes from surgical samples correspond to prognostic categories. PMID: 25445327 Ref: Thrombospondin-1 in a Murine Model of Colorectal Carcinogenesis. PMID: 26461935 Ref: Molecular profiling of cetuximab and bevacizumab treatment of colorectal tumours reveals perturbations in metabolic and hypoxic response pathways. PMID: 26517691 Ref: Optimization of Ammonium Sulfate Concentration for Purification of Colorectal Cancer Vaccine Candidate Recombinant Protein GA733-FcK Isolated from Plants. PMID: 26640471 |
Ref: Dietary fat overcomes the protective activity of thrombospondin-1 signaling in the Apc(Min/+) model of colon cancer. PMID: 27239962 Ref: Thrombospondin-1 Mimetic Agonist Peptides Induce Selective Death in Tumor Cells: Design, Synthesis, and Structure-Activity Relationship Studies. PMID: 27526615 |
Ref: 15-Lipoxygenase-1 re-expression in colorectal cancer alters endothelial cell features through enhanced expression of TSP-1 and ICAM-1. PMID: 28757355 |
Ref: Co-inhibition of BET proteins and NF-kappaB as a potential therapy for colorectal cancer through synergistic inhibiting MYC and FOXM1 expressions. PMID: 29472532 Ref: The TGFbeta-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs. PMID: 29986714 |