Primary Site >> Stomach Cancer

Gene >> TGFBR1

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Ref: Reduced levels of transforming growth factor-beta type I receptor in human gastric carcinomas.
PMID: 1312080
Ref: Transcriptional repression of the transforming growth factor-beta type I receptor gene by DNA methylation results in the development of TGF-beta resistance in human gastric cancer.
PMID: 10602482
Ref: [Proliferative changes of human gastric mucosa cells in different pathological lesions and their clinical significance].
PMID: 15355661
Ref: Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling.
PMID: 17307870
Ref: Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway.
PMID: 18174246
Ref: Extensive alteration in the expression profiles of TGFB pathway signaling components and TP53 is observed along the gastric dysplasia-carcinoma sequence.
PMID: 18830930
Ref: Inhibitory effect of a TGFbeta receptor type-I inhibitor, Ki26894, on invasiveness of scirrhous gastric cancer cells.
PMID: 20145621
Ref: Combination effect of a TGF-beta receptor kinase inhibitor with 5-FU analog S1 on lymph node metastasis of scirrhous gastric cancer in mice.
PMID: 20518790
Ref: Immunohistochemical expression of TGF beta (TGF-beta), TGF beta receptor 1 (TGFBR1), and Ki67 in intestinal variant of gastric adenocarcinomas.
PMID: 23188426
Ref: TGFBR1 tagging SNPs and gastric cancer susceptibility: a two-stage case-control study in Chinese population.
PMID: 22911926
Ref: Integrative identification of Epstein-Barr virus-associated mutations and epigenetic alterations in gastric cancer.
PMID: 25173755
Ref: Claudin 1 mediates tumor necrosis factor alpha-induced cell migration in human gastric cancer cells.
PMID: 25548484
Ref: Genetic alterations and their clinical implications in gastric cancer peritoneal carcinomatosis revealed by whole-exome sequencing of malignant ascites.
PMID: 26811494
Ref: Activation of Transforming Growth Factor Beta 1 Signaling in Gastric Cancer-associated Fibroblasts Increases Their Motility, via Expression of Rhomboid 5 Homolog 2, and Ability to Induce Invasiveness of Gastric Cancer Cells.
PMID: 28390866
Ref: Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers.
PMID: 28522256
Ref: Identification of recurrent risk-related genes and establishment of support vector machine prediction model for gastric cancer.
PMID: 29788739