Primary Site >> Pancreatic Cancer

Gene >> TGFB2

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Ref: Attenuated ALK5 receptor expression in human pancreatic cancer: correlation with resistance to growth inhibition.
PMID: 8760600
Ref: Biologic instability of pancreatic cancer xenografts in the nude mouse.
PMID: 10836999
Ref: Retinoic acid-dependent transforming growth factor-beta 2-mediated induction of MUC4 mucin expression in human pancreatic tumor cells follows retinoic acid receptor-alpha signaling pathway.
PMID: 10938282
Ref: Altered expression of TGFB receptors and mitogenic effects of TGFB in pancreatic carcinomas.
PMID: 11408925
Ref: Transforming growth factor-beta 2 is a transcriptional target for Akt/protein kinase B via forkhead transcription factor.
PMID: 12011061
Ref: Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.
PMID: 15289325
Ref: Cytokine expression profile in human pancreatic carcinoma cells and in surgical specimens: implications for survival.
PMID: 16094523
Ref: Targeted tumor therapy with the TGF-beta 2 antisense compound AP 12009.
PMID: 16377233
Ref: MUC4-expressing pancreatic adenocarcinomas show elevated levels of both T1 and T2 cytokines: potential pathobiologic implications.
PMID: 17032197
Ref: Foxp3 expression in pancreatic carcinoma cells as a novel mechanism of immune evasion in cancer.
PMID: 17804750
Ref: On the role of transforming growth factor-beta in the growth inhibitory effects of retinoic acid in human pancreatic cancer cells.
PMID: 18157915
Ref: Antisense therapeutics for tumor treatment: the TGF-beta2 inhibitor AP 12009 in clinical development against malignant tumors.
PMID: 18084956
Ref: Transforming growth factor-beta 2 gene silencing with trabedersen (AP 12009) in pancreatic cancer.
PMID: 21366804
Ref: The antisense oligonucleotide trabedersen (AP 12009) for the targeted inhibition of TGF-beta2.
PMID: 21619536
Ref: Clinical studies in the second line setting of advanced pancreatic cancer: are we making any progress?
PMID: 22797389
Ref: Development of a unique mouse model for pancreatic cancer lymphatic metastasis.
PMID: 22941445
Ref: Vasohibin-1 expression is regulated by transforming growth factor-beta/bone morphogenic protein signaling pathway between tumor-associated macrophages and pancreatic cancer cells.
PMID: 23651239
Ref: HOXA10 promotes cell invasion and MMP-3 expression via TGFbeta2-mediated activation of the p38 MAPK pathway in pancreatic cancer cells.
PMID: 24464212
Ref: Biomarkers of TGF-beta signaling pathway and prognosis of pancreatic cancer.
PMID: 24465802
Ref: Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer.
PMID: 26279302
Ref: Paracrine tumor signaling induces transdifferentiation of surrounding fibroblasts.
PMID: 26467073
Ref: microRNA-193a stimulates pancreatic cancer cell repopulation and metastasis through modulating TGF-beta2/TGF-betaRIII signalings.
PMID: 29433538