Primary Site >> Colorectal Cancer
Gene >> TGFB1
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Ref: Induction of carcinoembryonic antigen secretion and modulation of protein secretion/expression and fibronectin/laminin expression in human colon carcinoma cells by transforming growth factor-beta. PMID: 3289738 |
Ref: Transforming growth factor-beta 1: histochemical localization with antibodies to different epitopes. PMID: 2465297 Ref: Differential sensitivity of subclasses of human colon carcinoma cell lines to the growth inhibitory effects of transforming growth factor-beta 1. PMID: 2538337 Ref: Growth factor production by human colon carcinoma cell lines. PMID: 2541895 Ref: Expression of TGF-alpha/EGF and TGF-beta receptors in human colon carcinoma cell lines. PMID: 2545633 Ref: Clonal stimulation or inhibition of human colon carcinomas and human renal carcinomas mediated by transforming growth factor-beta 1. PMID: 2561734 Ref: Transforming growth factor-beta in intestinal epithelial differentiation and neoplasia (review). PMID: 2697192 |
Ref: Modulation of differentiation and proliferation in human colon carcinoma cells by transforming growth factor beta 1 and beta 2. PMID: 1697568 Ref: Inhibitory effects of transforming growth factor beta 1 on mitogenic response, transforming growth factor alpha, and c-myc in quiescent, well-differentiated colon carcinoma cells. PMID: 1701348 Ref: Investigation of cytokine gene expression in human colorectal cancer. PMID: 2114216 Ref: Growth factors and oncogenes in human gastrointestinal carcinomas. PMID: 2157713 Ref: Evidence for c-myc in the signaling pathway for TGF-beta in well-differentiated human colon carcinoma cells. PMID: 2273056 Ref: Growth-regulatory factors for normal, premalignant, and malignant human cells in vitro. PMID: 2404378 |
Ref: Proteins secreted by Caco-2 cells support growth of other tumor cells in Chee's Essential Medium without supplements. PMID: 1769010 |
Ref: Transforming growth factors and related peptides in gastrointestinal neoplasia. PMID: 1335097 Ref: Role of protein kinase C in transforming growth factor-beta 1 induction of carcinoembryonic antigen in human colon carcinoma cells. PMID: 1380512 Ref: Growth stimulation of a human colorectal carcinoma cell line by interleukin-1 and -6 and antagonistic effects of transforming growth factor beta 1. PMID: 1389533 Ref: Analysis of factors associated with the tumorigenic potential of 12 tumor clones derived from a single rat colon adenocarcinoma. PMID: 1459734 Ref: Sodium butyrate alters the response of a human colon carcinoma cell line to transforming growth factor-beta 1. PMID: 1555205 Ref: Regulation of human colon-carcinoma cell adhesion to extracellular matrix by transforming growth factor beta 1. PMID: 1555895 Ref: Transforming growth factor beta 1 (TGF-beta 1) inhibits retinoblastoma gene expression but not pRB phosphorylation in TGF-beta 1-growth stimulated colon carcinoma cells. PMID: 1565477 Ref: Responsiveness of three newly established human colorectal cancer cell lines to transforming growth factors beta 1 and beta 2. PMID: 1617643 Ref: Inhibition of colon and breast carcinoma cell growth by interleukin-4. PMID: 1728401 Ref: TGF-beta 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector. PMID: 1730743 |
Ref: [Role of TGF beta 1 in the stromal reaction to human colonic tumors]. PMID: 8173175 Ref: The role of growth regulatory aberrations in progression of human colon carcinoma. PMID: 8281613 Ref: TGF-beta expression in the human colon: differential immunostaining along crypt epithelium. PMID: 8318404 Ref: A 60-kD protein mediates the binding of transforming growth factor-beta to cell surface and extracellular matrix proteoglycans. PMID: 8335695 Ref: In vitro models of human colorectal cancer. PMID: 8348534 Ref: Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer. PMID: 8397167 Ref: Up-regulation of transforming growth factor alpha expression by transforming growth factor beta 1, epidermal growth factor, and N,N-dimethylformamide in human colon carcinoma cells. PMID: 8398905 Ref: Repression of autocrine transforming growth factor beta 1 and beta 2 in quiescent CBS colon carcinoma cells leads to progression of tumorigenic properties. PMID: 8494782 Ref: Induction of markers of normal differentiation in human colon carcinoma cells by the v-rasH oncogene. PMID: 8494794 |
Ref: TGF-beta 1 augments expression of the TIS10/prostaglandin synthase-2 gene in intestinal epithelial cells. PMID: 7787883 Ref: The role of nm23 in transforming growth factor beta 1-mediated adherence and growth arrest. PMID: 7819128 Ref: Characterization of mutated transforming growth factor-beta s which possess unique biological properties. PMID: 7918451 Ref: Expression of antisense fibronectin RNA in human colon carcinoma cells disrupts the regulation of carcinoembryonic antigen by transforming growth factor beta 1. PMID: 7961830 Ref: The capacity for growth stimulation by TGF beta 1 seen only in advanced colon cancers cannot be ascribed to mutations in APC, DCC, p53 or ras. PMID: 7970729 Ref: The role of transforming growth factor beta 1 in the fibroblastic reaction associated with rat colorectal tumor development. PMID: 7987852 Ref: Colon carcinoma cells switch their response to transforming growth factor beta 1 with tumor progression. PMID: 8018559 Ref: Trefoil peptides promote epithelial migration through a transforming growth factor beta-independent pathway. PMID: 8040278 Ref: Hepatocyte growth factor/scatter factor modulates intestinal epithelial cell proliferation and migration. PMID: 8048940 Ref: Autocrine transforming growth factor-beta 1 and beta 2 expression is increased by cell crowding and quiescence in colon carcinoma cells. PMID: 8082724 Ref: A benign cultured colon adenoma bears three genetically altered colon cancer oncogenes, but progresses to tumorigenicity and transforming growth factor-beta independence without inactivating the p53 tumor suppressor gene. PMID: 8132740 Ref: Two different signal transduction pathways can be activated by transforming growth factor beta 1 in epithelial cells. PMID: 8175753 Ref: Regulation of fibronectin and laminin receptor expression, fibronectin and laminin secretion in human colon cancer cells by transforming growth factor-beta 1. PMID: 8194884 |
Ref: Autocrine transforming growth factor beta 1 modulates the expression of integrin alpha 5 beta 1 in human colon carcinoma FET cells. PMID: 7539800 Ref: High levels of transforming growth factor beta 1 correlate with disease progression in human colon cancer. PMID: 7549813 Ref: Involvement of a transforming-growth-factor-beta-like molecule in tumor-cell-derived inhibition of nitric-oxide synthesis in cerebral endothelial cells. PMID: 7558424 Ref: Platelet-derived growth factor-B increases colon cancer cell growth in vivo by a paracrine effect. PMID: 7593201 Ref: Clonal heterogeneity of the sensitivity of human colon carcinoma cell lines to TGE beta isoforms. PMID: 7593230 Ref: Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells. PMID: 7665626 Ref: Transforming growth factor beta isoform-specific differences in interactions with type I and II transforming growth factor beta receptors. PMID: 7743502 Ref: Role of protein kinase C alpha in the induction of carcinoembryonic antigen by transforming growth factor beta 1. PMID: 7790386 Ref: Colon cancer cells that are not growth inhibited by TGF-beta lack functional type I and type II TGF-beta receptors. PMID: 7794080 Ref: Transforming growth factor beta 1 (TGF beta 1) is an autocrine positive regulator of colon carcinoma U9 cells in vivo as shown by transfection of a TGF beta 1 antisense expression plasmid. PMID: 9019169 |
Ref: High levels of transforming growth factor beta 1 in patients with colorectal cancer: association with disease progression. PMID: 8566583 Ref: Differential effect of interleukin-4 and transforming growth factor beta 1 on expression of proto-oncogenes and autocrine insulin-like growth factor II in colorectal carcinoma cells. PMID: 8645306 Ref: Reduced expression of transforming growth factor beta type I receptor contributes to the malignancy of human colon carcinoma cells. PMID: 8663343 Ref: Involvement of transforming growth factor beta1 in autocrine enhancement of gelatinase B secretion by murine metastatic colon carcinoma cells. PMID: 8764135 Ref: Differential control of expression of type I and type II receptors of transforming growth factor-beta in colon carcinoma cells. PMID: 8816926 Ref: Radio-induced modulation of transforming growth factor beta1 sensitivity in a p53 wild-type human colorectal-cancer cell line. PMID: 8895552 Ref: Cytokines may influence tumor growth and spread. An in vitro study in two human cancer cell lines. PMID: 9007614 Ref: Autocrine transforming growth factor-beta (TGF beta) modulates the 120 kD and 105 kD retinoblastoma (RB) protein species in CBS colon carcinoma cells as revealed by an anti-sense TGF beta 1 expression vector. PMID: 21544384 |
Ref: Control of fibronectin receptor expression by fibronectin: antisense fibronectin RNA downmodulates the induction of fibronectin receptor by transforming growth factor beta1. PMID: 9009142 Ref: Oral administration of PSK can improve the impaired anti-tumor CD4+ T-cell response in gut-associated lymphoid tissue (GALT) of specific-pathogen-free mice. PMID: 9033641 Ref: TGF-beta receptors and signal transduction. PMID: 9071813 Ref: Growth stimulation of colorectal carcinoma cells via the c-kit receptor is inhibited by TGF-beta 1. PMID: 9207920 Ref: Differential influence of TGFbeta1 and TGFbeta3 isoforms on cell cycle kinetics and postirradiation recovery of normal and malignant colorectal epithelial cells. PMID: 9212022 Ref: Function of the type V transforming growth factor beta receptor in transforming growth factor beta-induced growth inhibition of mink lung epithelial cells. PMID: 9228067 Ref: Oncogene and cytokine expression of human colorectal tumors responding to immunotherapy. PMID: 9336744 Ref: Colon carcinoma cell lines stimulate monocytes and lamina propria mononuclear cells to produce IL-10. PMID: 9367416 Ref: TGF-beta1 in colonic neoplasia: a genetic molecular and immunohistochemical study. PMID: 9387902 Ref: Modulation of p53 expression in cultured colonic adenoma cell lines by the naturally occurring lumenal factors butyrate and deoxycholate. PMID: 9398049 |
Ref: Protein kinase Calpha controls the adhesion but not the antiproliferative response of human colon carcinoma cells to transforming growth factor beta1: identification of two distinct branches of post-protein kinase Calpha adhesion signal pathway. PMID: 9564886 Ref: Transfection of the type II TGF-beta receptor into colon cancer cells increases receptor expression, inhibits cell growth, and reduces the malignant phenotype. PMID: 9637541 Ref: A subset of metastatic human colon cancers expresses elevated levels of transforming growth factor beta1. PMID: 9641494 Ref: Smad3 mutant mice develop metastatic colorectal cancer. PMID: 9753318 Ref: Controlled release of TGF-beta1 impedes rat colon carcinogenesis in vivo. PMID: 9808532 Ref: Direct action of a protein-bound polysaccharide, PSK, on transforming growth factor-beta. PMID: 9858065 |
Ref: Coordinate regulation of cyclooxygenase-2 and TGF-beta1 in replication error-positive colon cancer and azoxymethane-induced rat colonic tumors. PMID: 10069452 Ref: Transforming growth factor beta stimulation of colorectal cancer cell lines: type II receptor bypass and changes in adhesion molecule expression. PMID: 10077641 Ref: Elevated serum levels of transforming growth factor-beta1 in patients with colorectal carcinoma: its association with tumor progression and its significant decrease after curative surgical resection. PMID: 10091729 Ref: Mutational analysis of activin/transforming growth factor-beta type I and type II receptor kinases in human pituitary tumors. PMID: 10323406 Ref: Evidence for control of nitric oxide synthesis by intracellular transforming growth factor-beta1 in tumor cells. Implications for tumor development. PMID: 10362813 Ref: Down-regulation of TGF-beta receptors in human colorectal cancer: implications for cancer development. PMID: 10389996 Ref: Role of fibroblasts in HGF/SF-induced cohort migration of human colorectal carcinoma cells: fibroblasts stimulate migration associated with increased fibronectin production via upregulated TGF-beta1. PMID: 10399964 Ref: Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis. PMID: 10416598 Ref: Factor XIII modulates intestinal epithelial wound healing in vitro. PMID: 10423064 Ref: An interaction between human colon carcinoma cells and hepatocytes activates transforming growth factor-beta1 in vitro. PMID: 10424785 Ref: Contextual effects of transforming growth factor beta on the tumorigenicity of human colon carcinoma cells. PMID: 10493532 Ref: Suppression of the reactive oxygen intermediates production of human macrophages by colorectal adenocarcinoma cell lines. PMID: 10594687 |
Ref: Molecular profiling of sporadic colorectal tumors by microsatellite analysis. PMID: 10601563 Ref: Effects of transforming growth factor beta1 expression in a rat colon carcinoma: growth inhibition, leukocyte infiltration and production of interleukin-10 and tumor necrosis factor alpha. PMID: 10630310 Ref: Mechanical deformation induces proliferation of human colorectal carcinoma cells. PMID: 10675497 Ref: Molecular interactions in the Vogelstein model of colorectal carcinoma. PMID: 10699988 Ref: Development of myofibroblasts from human bone marrow mesenchymal stem cells cocultured with human colon carcinoma cells and TGF beta 1. PMID: 10718362 Ref: [Effect of laminin antisense RNA on the expression of five intracellular proteins stimulated by transforming growth factor beta(1)]. PMID: 10751536 Ref: Secretion of extracellular matrix (fibronectin), growth factor (transforming growth factor beta) and protease (cathepsin D) by hepatoma cells. PMID: 10765130 Ref: Ito cell morphology, alpha-smooth muscle actin and collagen type IV expression in the liver of patients with gastric and colorectal tumors. PMID: 10841310 Ref: Genetic analysis of multiple sporadic colon carcinomas from a single patient. PMID: 10855548 Ref: IGFBP-3 mediates TGF beta 1 proliferative response in colon cancer cells. PMID: 10897042 Ref: Expression of transforming growth factor beta1 and its type II receptor in mouse colon tumors induced by azoxymethane. PMID: 10938397 Ref: [Mechanism of resistance to growth inhibition by transforming growth factor-beta 1 (TGF-beta 1) in primary lung cancer and new molecular targets in therapy]. PMID: 10945024 Ref: Microgravity culture reduces apoptosis and increases the differentiation of a human colorectal carcinoma cell line. PMID: 10949995 Ref: Genetic alterations of sporadic colorectal cancer with microsatellite instability, especially characteristics of primary multiple colorectal cancers. PMID: 10962455 Ref: Establishment and characterization of two new rectal neuroendocrine cell carcinoma cell lines. PMID: 11070410 Ref: [Response of metastatic colorectal cancers to treatment with CPT11 (irinotecan): implications of the mismatched base repair system]. PMID: 11084429 Ref: Abnormal distribution of collagen type IV in extrahepatic bile duct carcinoma. PMID: 11107064 |
Ref: Oncogenic Ki-ras confers a more aggressive colon cancer phenotype through modification of transforming growth factor-beta receptor III. PMID: 11029459 Ref: Disruption of transforming growth factor beta-regulated laminin receptor function by expression of antisense laminin, a chain RNA in human colon cancer cells. PMID: 11147813 Ref: Differential expression of transforming growth factors-beta1, -beta2 and -beta3 in human colon carcinoma. PMID: 11166150 Ref: Interleukin-10-deficient mice and inflammatory bowel disease associated cancer development. PMID: 11285204 Ref: Growth inhibition due to complementation of transforming growth factor-beta receptor type II-defect by human chromosome 3 transfer in human colorectal carcinoma cells. PMID: 11319759 Ref: Decreased levels of precursor transforming growth factor beta1 in human colorectal cancer. PMID: 11351271 Ref: Tributyrin enhances the cytotoxic activity of interleukin-2/interleukin-12 stimulated human natural killer cells against LS 174T colon cancer cells in vitro. PMID: 11401027 Ref: Enhanced apoptosis and transforming growth factor-beta1 expression in colorectal adenomas and carcinomas after Sulindac therapy. PMID: 11496082 Ref: Corticosteroids impair intestinal epithelial wound repair mechanisms in vitro. PMID: 11521988 Ref: Bacterial lipopolysaccharide induces transforming growth factor beta and hepatocyte growth factor through toll-like receptor 2 in cultured human colon cancer cells. PMID: 11725828 Ref: Ectopic expression of eIF-4E in human colon cancer cells promotes the stimulation of adhesion molecules by transforming growth factorbeta. PMID: 11771728 |
Ref: Transforming growth factor beta 1 induces proliferation in colon carcinoma cells by Ras-dependent, smad-independent down-regulation of p21cip1. PMID: 11784716 Ref: Significance of transforming growth factor beta1 as a new tumor marker for colorectal cancer. PMID: 11802214 Ref: Associated changes of lipid peroxidation and transforming growth factor beta1 levels in human colon cancer during tumour progression. PMID: 11839715 Ref: Enhanced growth of colorectal aberrant crypt foci in fasted/refed rats involves changes in TGFbeta1 and p21CIP expressions. PMID: 11872640 Ref: Leukocyte recruitment in colon cancer: role of cell adhesion molecules, nitric oxide, and transforming growth factor beta1. PMID: 11910362 Ref: Evaluation of screening strategy for detecting hereditary nonpolyposis colorectal carcinoma. PMID: 11920458 Ref: Conditional loss of TGF-beta signalling leads to increased susceptibility to gastrointestinal carcinogenesis in mice. PMID: 11966532 Ref: Extracellular domain of TGFbeta type III receptor inhibits angiogenesis and tumor growth in human cancer cells. PMID: 12032856 Ref: TGF beta1 expression and angiogenesis in colorectal cancer tissue. PMID: 12046078 Ref: A complex DNA-repeat structure within the Selenoprotein P promoter contains a functionally relevant polymorphism and is genetically unstable under conditions of mismatch repair deficiency. PMID: 12173025 Ref: Transforming growth factor-beta1 in invasion and metastasis in colorectal cancer. PMID: 12174377 Ref: Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer. PMID: 12208849 Ref: Transforming growth factor-beta 1 signaling contributes to Caco-2 cell growth inhibition induced by 1,25(OH)(2)D(3). PMID: 12223346 Ref: [Genetic pathways in colorectal cancer: interest for the pathologist]. PMID: 12410150 Ref: Elimination of colon cancer in germ-free transforming growth factor beta 1-deficient mice. PMID: 12438215 Ref: Altered expression of the receptor and ligand in the TGF beta signaling pathway in diffusely infiltrating colon carcinoma. PMID: 12552954 Ref: Expression and role of thrombospondin-1 in colorectal cancer. PMID: 12553016 |
Ref: Role of cyclooxygenase 2 in protein kinase C beta II-mediated colon carcinogenesis. PMID: 12480928 Ref: Converging signals synergistically activate the LAMC2 promoter and lead to accumulation of the laminin gamma 2 chain in human colon carcinoma cells. PMID: 12519076 Ref: Serrated adenomas and mixed polyposis caused by a splice acceptor deletion in the mouse Smad4 gene. PMID: 12557227 Ref: SMAD7 is a prognostic marker in patients with colorectal cancer. PMID: 12584741 Ref: Defective processing of the transforming growth factor-beta1 in azoxymethane-induced mouse colon tumors. PMID: 12720300 Ref: Both high intratumoral microvessel density determined using CD105 antibody and elevated plasma levels of CD105 in colorectal cancer patients correlate with poor prognosis. PMID: 12778073 Ref: Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids. PMID: 12802055 Ref: Transforming growth factor beta 1 increases the stability of p21/WAF1/CIP1 protein and inhibits CDK2 kinase activity in human colon carcinoma FET cells. PMID: 12810668 Ref: Mutational analysis of TGF-beta type II receptor, Smad2, Smad3, Smad4, Smad6 and Smad7 genes in colorectal cancer. PMID: 12866583 Ref: The loss of TGF-beta signaling promotes prostate cancer metastasis. PMID: 12869309 Ref: 4-hydroxynonenal and transforming growth factor-beta1 expression in colon cancer. PMID: 12893005 Ref: Tumor suppressor function of Betaig-h3 gene in radiation carcinogenesis. PMID: 12971413 Ref: Fas ligand mediates immune privilege and not inflammation in human colon cancer, irrespective of TGF-beta expression. PMID: 14520470 Ref: Increased serum transforming growth factor-beta1 in human colorectal cancer correlates with reduced circulating dendritic cells and increased colonic Langerhans cell infiltration. PMID: 14616787 Ref: Relationship between expression of CD105 and growth factors in malignant tumors of gastrointestinal tract and its significance. PMID: 14669355 Ref: Matrix metalloproteinase-21 is expressed epithelially during development and in cancer and is up-regulated by transforming growth factor-beta1 in keratinocytes. PMID: 14691307 |
Ref: LY317615 decreases plasma VEGF levels in human tumor xenograft-bearing mice. PMID: 14593497 Ref: Expression of TGF beta1 genes and their receptor types I, II, and III in low- and high-grade malignancy non-Hodgkin's lymphomas. PMID: 14704634 Ref: The potential role of TGFbeta1, TGFbeta2 and TGFbeta3 protein expression in colorectal carcinomas. Correlation with classic histopathologic factors and patient survival. PMID: 15057430 Ref: [Alterations of p53 gene and microsatellite instability in ulcerative colitis and ulcerative colitis-associated colorectal cancer]. PMID: 15067728 Ref: Transforming growth factor-beta1 induced hepatocyte apoptosis--a possible mechanism for growth of colorectal liver metastasis. PMID: 15068326 Ref: [Colorectal carcinogenesis: update]. PMID: 15086056 Ref: Transforming growth factor beta regulates cell-cell adhesion through extracellular matrix remodeling and activation of focal adhesion kinase in human colon carcinoma Moser cells. PMID: 15133493 Ref: Tumour seeding in peritoneal wound sites in relation to growth-factor expression in early granulation tissue. PMID: 15177504 Ref: Elevated TGF-beta1 secretion and down-modulation of NKG2D underlies impaired NK cytotoxicity in cancer patients. PMID: 15187109 Ref: Glucagon-like peptide 2 improves intestinal wound healing through induction of epithelial cell migration in vitro-evidence for a TGF--beta-mediated effect. PMID: 15256284 Ref: Inhibition of proliferation and induction of apoptosis by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide in adult T-cell leukemia cells. PMID: 15276867 Ref: Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-beta or wounding. PMID: 15331629 Ref: alpha2HS-glycoprotein, an antagonist of transforming growth factor beta in vivo, inhibits intestinal tumor progression. PMID: 15374947 Ref: Effects of culture with TNF-alpha, TGF-beta and insulin on sulphotransferase (SULT 1A1 and 1A3) activity in human colon and neuronal cell lines. PMID: 15465639 Ref: Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung. PMID: 15466481 Ref: [The repetitive immune cell transfer therapy combining non-myelosuppressive chemotherapy for patients with advanced and refractory cancer]. PMID: 15553672 Ref: [Variation of cytokines with administration of chemotherapeutic and immuno-therapeutic drugs for colorectal cancer]. PMID: 15553673 |
Ref: Quinoxaline 1,4-dioxides induce G2/M cell cycle arrest and apoptosis in human colon cancer cells. PMID: 15538569 Ref: IL-6 signaling promotes tumor growth in colorectal cancer. PMID: 15655344 Ref: TGF-beta signaling in colon cancer cells. PMID: 15711891 Ref: Transforming growth factor beta can be a parameter of aggressiveness of pT1 colorectal cancer. PMID: 15754403 Ref: Inhibitory effect of genistein on mouse colon cancer MC-26 cells involved TGF-beta1/Smad pathway. PMID: 15963949 Ref: Lack of an association between serum level of transforming growth factor beta -1 and stomach cancer risk in the JACC study. PMID: 16101328 Ref: Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses. PMID: 16135802 Ref: Evaluation of the interaction between TGF beta and nitric oxide in the mechanisms of progression of colon carcinoma. PMID: 16170670 Ref: Transforming growth factor-beta promotes pro-fibrotic behavior by serosal fibroblasts via PKC and ERK1/2 mitogen activated protein kinase cell signaling. PMID: 16327498 Ref: 4-hydroxynonenal and TGF-beta1 concur in inducing antiproliferative effects on the CaCo-2 human colon adenocarcinoma cell line. PMID: 16403984 |
Ref: Endoglin (CD105) expression in angiogenesis of colon cancer: analysis using tissue microarrays and comparison with other endothelial markers. PMID: 16177881 Ref: Role of Smad proteins in the regulation of NF-kappaB by TGF-beta in colon cancer cells. PMID: 16288847 Ref: TGF-beta as a T cell regulator in colitis and colon cancer. PMID: 16298544 Ref: Evi1 is a survival factor which conveys resistance to both TGFbeta- and taxol-mediated cell death via PI3K/AKT. PMID: 16462766 Ref: Obese state leads to elevated levels of TGF-beta and COX isoforms in platelets of Zucker rats. PMID: 16477387 Ref: Interaction between stromal fibroblasts and colorectal cancer cells in the expression of vascular endothelial growth factor. PMID: 16600304 Ref: Dietary fiber enhances a tumor suppressor signaling pathway in the gut. PMID: 16632996 Ref: c-Fos is required for TGFbeta1 production and the associated paracrine migratory effects of human colon carcinoma cells. PMID: 16637060 Ref: Analysis of gene expression profile in colon cancer using the Cancer Genome Anatomy Project and RNA interference. PMID: 16643337 Ref: In vivo luminescent imaging of cyclosporin A-mediated cancer progression in rats. PMID: 16770245 Ref: c-Jun N-terminal kinase upregulation as a key event in the proapoptotic interaction between transforming growth factor-beta1 and 4-hydroxynonenal in colon mucosa. PMID: 16843825 Ref: Expression of Smad4 and TGF-beta2 in colorectal carcinoma. PMID: 16886611 Ref: [EVI1 and its role in myelodysplastic syndrome, myeloid leukemia and other malignant diseases]. PMID: 16995417 Ref: [Mechanisms of metastasis and molecular markers of malignant tumor progression. I. Colorectal cancer]. PMID: 17013365 Ref: Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation. PMID: 17047044 Ref: Organ-specific endoglin (CD105) expression in the angiogenesis of human cancers. PMID: 17096728 Ref: Study of interleukin-6 in the spread of colorectal cancer: the diagnostic significance of IL-6. PMID: 17189976 Ref: Regulatory cytokine gene polymorphisms and risk of colorectal carcinoma. PMID: 17261758 |
Ref: Genetic alterations of the TGF-beta signaling pathway in colorectal cancer cell lines: a novel mutation in Smad3 associated with the inactivation of TGF-beta-induced transcriptional activation. PMID: 16828225 Ref: Expression of TGF-beta1, TbetaRII and Smad4 in colorectal carcinoma. PMID: 17289018 Ref: Smad4 regulates claudin-1 expression in a transforming growth factor-beta-independent manner in colon cancer cells. PMID: 17308096 Ref: Modulation of CD103 expression on human colon carcinoma-specific CTL. PMID: 17312135 Ref: Antitumor effects of Nafamostat mesilate on head and neck squamous cell carcinoma. PMID: 17337140 Ref: Consumption of prebiotic inulin enriched with oligofructose in combination with the probiotics Lactobacillus rhamnosus and Bifidobacterium lactis has minor effects on selected immune parameters in polypectomised and colon cancer patients. PMID: 17349080 Ref: Transforming growth factor beta 1 and metalloproteinase-9 overexpression in colorectal cancer (CC) and adenoma. PMID: 17394006 Ref: TGF-beta1 and TNF-alpha after red blood cell transfusion in colorectal cancer patients. PMID: 17431392 Ref: Role of complement regulatory proteins in the survival of murine allo-transplanted Sertoli cells. PMID: 17449937 Ref: The TGFbeta/Smad 3-signaling pathway is involved in butyrate-mediated vitamin D receptor (VDR)-expression. PMID: 17471513 Ref: TGF-beta signaling alterations and susceptibility to colorectal cancer. PMID: 17613544 Ref: Transforming growth factor beta 1 (TGFB1) gene polymorphisms and risk of advanced colorectal adenoma. PMID: 17615257 Ref: Transforming growth factor beta-1 in rectal tumour, mucosa and plasma in relation to radiotherapy and clinical outcome in rectal cancer patients. PMID: 17657504 Ref: TGF-beta receptor 2 downregulation in tumour-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: a retrospective study. PMID: 17692120 Ref: The significance of serum transforming growth factor beta 1 in detecting of gastric and colon cancers. PMID: 17708279 Ref: Microsatellite unstable colorectal cancer cell lines with truncating TGFbetaRII mutations remain sensitive to endogenous TGFbeta. PMID: 17893910 Ref: Sulfated glycosphingolipid as mediator of phagocytosis: SM4s enhances apoptotic cell clearance and modulates macrophage activity. PMID: 17982067 Ref: TGFbeta1 expression in colonic mucosa: modulation by dietary lipids. PMID: 18850178 |
Ref: Regulation of human Cripto-1 gene expression by TGF-beta1 and BMP-4 in embryonal and colon cancer cells. PMID: 17941089 Ref: Mutational inactivation of TGFBR2 in microsatellite unstable colon cancer arises from the cooperation of genomic instability and the clonal outgrowth of transforming growth factor beta resistant cells. PMID: 17985359 Ref: The bone morphogenetic protein pathway is active in human colon adenomas and inactivated in colorectal cancer. PMID: 18008360 Ref: Colorectal cancer cells express functional cell surface-bound TGFbeta. PMID: 18076044 Ref: Increased TGF-beta 1 protein expression in patients with advanced colorectal cancer. PMID: 18176914 Ref: Differential Notch and TGFbeta signaling in primary colorectal tumors and their corresponding metastases. PMID: 18219106 Ref: Lack of interleukin-4 receptor alpha chain-dependent signalling promotes azoxymethane-induced colorectal aberrant crypt focus formation in Balb/c mice. PMID: 18220315 Ref: Association of genetic variation in the transforming growth factor beta-1 gene with serum levels and risk of colorectal neoplasia. PMID: 18281501 Ref: Transforming growth factor beta suppresses beta-catenin/Wnt signaling and stimulates an adhesion response in human colon carcinoma cells in a Smad4/DPC4 independent manner. PMID: 18367323 Ref: Differential impact of TGF-beta and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion. PMID: 18423981 Ref: The aberrant methylation of TSP1 suppresses TGF-beta1 activation in colorectal cancer. PMID: 18425817 Ref: Foxp3 expression in human cancer cells. PMID: 18430198 Ref: Functional classification analysis of somatically mutated genes in human breast and colorectal cancers. PMID: 18434084 Ref: Transforming growth factor beta induces apoptosis through repressing the phosphoinositide 3-kinase/AKT/survivin pathway in colon cancer cells. PMID: 18451140 Ref: The contribution of animal fat oxidation products to colon carcinogenesis, through modulation of TGF-beta1 signaling. PMID: 18453540 Ref: Estrogen receptor beta deficiency enhances small intestinal tumorigenesis in ApcMin/+ mice. PMID: 18464259 Ref: TGFbeta modulates PTEN expression independently of SMAD signaling for growth proliferation in colon cancer cells. PMID: 18769113 Ref: Switch of transforming growth factor beta function from tumor suppression to stimulation in adenomatous polyposis coli (APC) knocked-down human colon carcinoma cells. PMID: 18774639 Ref: Colorectal cancers in patients with the (9A/6A) polymorphism of TGFBR1 exhibit lesser inter-(simple sequence repeat) PCR genomic instability and present clinically at greater age. PMID: 18778720 Ref: Soluble transforming growth factor beta type II receptor attenuates TGF-beta1 activity in human colorectal cancer LoVo cells. PMID: 19020727 Ref: [Anticancer effects of tea polyphenols on colorectal cancer with microsatellite instability in nude mice]. PMID: 19063841 Ref: TIMP-1 expression in human colorectal cancer is associated with TGF-B1, LOXL2, INHBA1, TNF-AIP6 and TIMP-2 transcript profiles. PMID: 19383344 |
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