Primary Site >> Biliary tract Cancer

Gene >> TGFB1

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Ref: Cell proliferation and oncogene expression after bile duct ligation in the rat: evidence of a specific growth effect on bile duct cells.
PMID: 7705781
Ref: [Hepatic neoductules].
PMID: 8600693
Ref: [Effect of recombinant human basic fibroblast growth factor (bFGF) on the growth of human tumor cell lines].
PMID: 9183641
Ref: Autocrine and paracrine motility factors and their involvement in invasiveness in a human oral carcinoma cell line.
PMID: 10468286
Ref: Disrupted transforming growth factor-beta signaling and deregulated growth in human biliary tract cancer cells.
PMID: 10842191
Ref: Growth control of human biliary epithelial cells by interleukin 6, hepatocyte growth factor, transforming growth factor beta1, and activin A: comparison of a cholangiocarcinoma cell line with primary cultures of non-neoplastic biliary epithelial cells.
PMID: 10869285
Ref: Abnormal distribution of collagen type IV in extrahepatic bile duct carcinoma.
PMID: 11107064
Ref: Immunohistochemical analysis of transforming growth factor beta in gallbladder cancer.
PMID: 12579267
Ref: Transforming growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cells.
PMID: 12615726
Ref: Expression of transforming growth factor betas and their signaling receptors in stone-containing intrahepatic bile ducts and cholangiocarcinoma.
PMID: 12917766
Ref: Evaluation of BAT-26 as an indicator of microsatellite instability in gallbladder carcinomas.
PMID: 14696408
Ref: Influence of the site of human gallbladder xenograft (Mz-ChA-1) on angiogenesis at the distant site.
PMID: 15010876
Ref: Intrahepatic cholangiocarcinoma escapes from growth inhibitory effect of transforming growth factor-beta1 by overexpression of cyclin D1.
PMID: 15696189
Ref: [Expression of Smad4 and transforming growth factor-beta1, transforming growth factor-beta receptor II in cholangiocarcinoma tissue and its biological significance].
PMID: 16083599
Ref: Local balance of transforming growth factor-beta1 secreted from cholangiocarcinoma cells and stromal-derived factor-1 secreted from stromal fibroblasts is a factor involved in invasion of cholangiocarcinoma.
PMID: 16792547
Ref: Effect of transforming growth factor-beta1 on human intrahepatic cholangiocarcinoma cell growth.
PMID: 17072955
Ref: Restoration of RUNX3 enhances transforming growth factor-beta-dependent p21 expression in a biliary tract cancer cell line.
PMID: 17470130
Ref: Thalidomide attenuates tumor growth and preserves fast-twitch skeletal muscle fibers in cholangiocarcinoma rats.
PMID: 18291259
Ref: Genetic susceptibility of epidermal growth factor +61A>G and transforming growth factor beta1 -509C>T gene polymorphisms with gallbladder cancer.
PMID: 18571008
Ref: Epithelial-mesenchymal transition induced by transforming growth factor-{beta}1/Snail activation aggravates invasive growth of cholangiocarcinoma.
PMID: 20489148
Ref: E/N-cadherin switch mediates cancer progression via TGF-beta-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma.
PMID: 22068819
Ref: Transforming growth factor-beta signaling promotes hepatocarcinogenesis induced by p53 loss.
PMID: 21898503
Ref: A zebrafish model of intrahepatic cholangiocarcinoma by dual expression of hepatitis B virus X and hepatitis C virus core protein in liver.
PMID: 22729936
Ref: Cytokines released from activated human macrophages induce epithelial mesenchymal transition markers of cholangiocarcinoma cells.
PMID: 23480772
Ref: Role of crosstalk between interleukin-6 and transforming growth factor-beta 1 in epithelial-mesenchymal transition and chemoresistance in biliary tract cancer.
PMID: 23298711
Ref: MiR-20a triggers metastasis of gallbladder carcinoma.
PMID: 23665284
Ref: Molecular profiling of stroma identifies osteopontin as an independent predictor of poor prognosis in intrahepatic cholangiocarcinoma.
PMID: 23775819
Ref: Hepatic myofibroblasts promote the progression of human cholangiocarcinoma through activation of epidermal growth factor receptor.
PMID: 23787814
Ref: JNK inhibitor SP600125 enhances TGF-beta-induced apoptosis of RBE human cholangiocarcinoma cells in a Smad-dependent manner.
PMID: 24100678
Ref: Protective Effects of Guava Pulp on Cholestatic Liver Injury.
PMID: 27335829
Ref: NT5E and FcGBP as key regulators of TGF-1-induced epithelial-mesenchymal transition (EMT) are associated with tumor progression and survival of patients with gallbladder cancer.
PMID: 24310606
Ref: Transcriptional profiles of peripheral blood leukocytes identify patients with cholangiocarcinoma and predict outcome.
PMID: 24935374
Ref: Transforming growth factor-beta1-induced epithelial-mesenchymal transition generates ALDH-positive cells with stem cell properties in cholangiocarcinoma.
PMID: 25194504
Ref: Autophagy may promote carcinoma cell invasion and correlate with poor prognosis in cholangiocarcinoma.
PMID: 25197362
Ref: Connective tissue growth factor and integrin alphavbeta6: a new pair of regulators critical for ductular reaction and biliary fibrosis in mice.
PMID: 25203810
Ref: Downregulation of FOXP3 inhibits invasion and immune escape in cholangiocarcinoma.
PMID: 25623530
Ref: CD109 is a novel marker for squamous cell/adenosquamous carcinomas of the gallbladder.
PMID: 26249215
Ref: Evaluation of prognostic significance of granulocyte-related factors in cancer patients undergoing personalized peptide vaccination.
PMID: 26325075
Ref: Integrin beta3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma.
PMID: 26517522
Ref: Epithelial Transforming Growth Factor-beta Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma.
PMID: 26627606
Ref: A Histone Deacetylase Inhibitor Suppresses Epithelial-Mesenchymal Transition and Attenuates Chemoresistance in Biliary Tract Cancer.
PMID: 26726879
Ref: Upregulation of H19 indicates a poor prognosis in gallbladder carcinoma and promotes epithelial-mesenchymal transition.
PMID: 27073719
Ref: Overexpression of LncRNA-ROR predicts a poor outcome in gallbladder cancer patients and promotes the tumor cells proliferation, migration, and invasion.
PMID: 27449039
Ref: Long non-coding RNA TUG1 promotes cell proliferation and metastasis by negatively regulating miR-300 in gallbladder carcinoma.
PMID: 28178615
Ref: Biliary epithelial injury-induced regenerative response by IL-33 promotes cholangiocarcinogenesis from peribiliary glands.
PMID: 28439013
Ref: Ring finger protein 125, as a potential highly aggressive and unfavorable prognostic biomarker, promotes the invasion and metastasis of human gallbladder cancers via activating the TGF- beta1-SMAD3-ID1 signaling pathway.
PMID: 28611292
Ref: TGF-beta signaling is an effective target to impair survival and induce apoptosis of human cholangiocarcinoma cells: A study on human primary cell cultures.
PMID: 28873435
Ref: Blocking ERK1/2 signaling impairs TGF-beta1 tumor promoting function but enhances its tumor suppressing role in intrahepatic cholangiocarcinoma cells.
PMID: 28959141
Ref: A novel transforming growth factor beta-induced long noncoding RNA promotes an inflammatory microenvironment in human intrahepatic cholangiocarcinoma.
PMID: 29507901
Ref: CD133 expression in cancer cells predicts poor prognosis of non-mucin producing intrahepatic cholangiocarcinoma.
PMID: 29510695
Ref: beta4 and beta6 Integrin Expression Is Associated with the Subclassification and Clinicopathological Features of Intrahepatic Cholangiocarcinoma.
PMID: 29584696
Ref: S100A11 promotes cell proliferation via P38/MAPK signaling pathway in intrahepatic cholangiocarcinoma.
PMID: 30182496