Primary Site >> Pancreatic Cancer
Gene >> TERT
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Ref: [Diagnostic value of serum level of alpha 2-macroglobulin-trypsin complex in pancreatic diseases using a colorimetric assay with a synthetic chromogenic substrate]. PMID: 1726222 |
Ref: Functional analysis of TCR gamma delta+ T cells in tumour-infiltrating lymphocytes (TIL) of human pancreatic cancer. PMID: 8370173 |
Ref: Expression profile of the putative catalytic subunit of the telomerase gene. PMID: 9485011 |
Ref: Establishment of quantitative reverse transcription--polymerase chain reaction assays for human telomerase-associated genes. PMID: 10660803 |
Ref: Telomerase reverse transcriptase and telomeric-repeat binding factor protein 1 as regulators of telomerase activity in pancreatic cancer cells. PMID: 11531263 |
Ref: Bax-induction gene therapy of pancreatic cancer. PMID: 12175991 Ref: Xenoantigen, an alphaGal epitope-expression construct driven by the hTERT-promoter, specifically kills human pancreatic cancer cell line. PMID: 12392598 |
Ref: Telomerase gene expression in intraductal papillary-mucinous tumors (IPMT): preliminary findings. PMID: 15055037 |
Ref: Serum tumor markers and molecular biological diagnosis in pancreatic cancer. PMID: 15084968 Ref: Suppressing orthotopic pancreatic tumor growth with a fiber-modified adenovector expressing the TRAIL gene from the human telomerase reverse transcriptase promoter. PMID: 15161713 Ref: [Adenoviral vector expressing the TRAIL gene driven by the hTERT promoter]. PMID: 15592959 |
Ref: Suppression of pancreatic tumor growth in the liver by systemic administration of the TRAIL gene driven by the hTERT promoter. PMID: 15486557 Ref: Quantitative assessment of telomerase activity and human telomerase reverse transcriptase messenger RNA levels in pancreatic juice samples for the diagnosis of pancreatic cancer. PMID: 15788678 Ref: Attenuation of telomerase activity by hammerhead ribozymes targeting human telomerase RNA and telomerase reverse transcriptase in pancreatic carcinoma cells. PMID: 15847061 Ref: Clinical usefulness of telomerase for the detection of colon cancer in ulcerative colitis patients. PMID: 16174077 |
Ref: Quantitative analysis of human telomerase reverse transcriptase in pancreatic cancer. PMID: 16609017 Ref: Inhibitory effects of antisense phosphorothioate oligodeoxynucleotides on pancreatic cancer cell Bxpc-3 telomerase activity and cell growth in vitro. PMID: 16810748 |
Ref: Analysis of hTERT mRNA expression in biliary tract and pancreatic cancer. PMID: 17384912 Ref: Inhibition of estrogen receptor beta-mediated human telomerase reverse transcriptase gene transcription via the suppression of mitogen-activated protein kinase signaling plays an important role in 15-deoxy-Delta(12,14)-prostaglandin J(2)-induced apoptosis PMID: 17706193 Ref: hTERT-targeted E. coli purine nucleoside phosphorylase gene/6-methylpurine deoxyribose therapy for pancreatic cancer. PMID: 17711742 Ref: GV-1001, an injectable telomerase peptide vaccine for the treatment of solid cancers. PMID: 17932813 |
Ref: Telomerase transcriptional targeting of inducible Bax/TRAIL gene therapy improves gemcitabine treatment of pancreatic cancer. PMID: 17984977 Ref: Detection of human telomerase reverse transcriptase (hTERT) expression in tissue and pancreatic juice from pancreatic cancer. PMID: 18154939 Ref: Effect of 5-LOX/COX-2 common inhibitor DHDMBF30 on pancreatic cancer cell Capan2. PMID: 18442195 |
Ref: Positive regulation of human telomerase reverse transcriptase gene expression and telomerase activity by DNA methylation in pancreatic cancer. PMID: 19194757 Ref: Usefulness of human telomerase reverse transcriptase in pancreatic juice as a biomarker of pancreatic malignancy. PMID: 19342980 Ref: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB. PMID: 19424592 Ref: Effect of c-MYC and E2F1 gene silencing and of 5-azacytidine treatment on telomerase activity in pancreatic cancer-derived cell lines. PMID: 19451745 Ref: [Effect of human telomerase reverse transcriptase gene antisense oligonucleotide on sensitivity of gemcitabine in pancreatic cancer cell]. PMID: 20137691 Ref: Antitumor efficacy of human telomerase reverse transcriptase gene antisense oligonucleotide in pancreatic cancer cells. PMID: 21475859 |
Ref: hTERT-promoter-dependent oncolytic adenovirus enhances the transduction and therapeutic efficacy of replication-defective adenovirus vectors in pancreatic cancer cells. PMID: 20059477 Ref: A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. PMID: 20101243 Ref: TGF-beta induces telomerase-dependent pancreatic tumor cell cycle arrest. PMID: 20138964 Ref: [Minimal residual disease in pancreatic cancer--our first experiences]. PMID: 20429336 Ref: Variation at the TERT locus and predisposition for cancer. PMID: 20478107 Ref: Transcriptional control of tight junction proteins via a protein kinase C signal pathway in human telomerase reverse transcriptase-transfected human pancreatic duct epithelial cells. PMID: 20566751 Ref: Knockdown of hTERT by SiRNA suppresses growth of Capan-2 human pancreatic cancer cell via the inhibition of expressions of Bcl-2 and COX-2. PMID: 20579221 Ref: ABO blood group and other genetic variants associated with pancreatic cancer. PMID: 20587082 Ref: [Possibility of using the determination of minimal residual disease in pancreatic adenocarcinoma using real-time RT-PCR--a pilot study]. PMID: 20662469 Ref: [Transfection of pancreatic cancer cells BxPC-3 with recombinant plasmid pSilencer4.1-CMV neo-hTERT-siRNA and its silencing effects]. PMID: 20813682 |
Ref: Marker expression in circulating cancer cells of pancreatic cancer patients. PMID: 20869080 Ref: hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes. PMID: 21365467 Ref: Effects of Clostridium perfringens enterotoxin via claudin-4 on normal human pancreatic duct epithelial cells and cancer cells. PMID: 21573709 Ref: Downregulation of tight junction-associated MARVEL protein marvelD3 during epithelial-mesenchymal transition in human pancreatic cancer cells. PMID: 21763689 Ref: Pancreatic cancer susceptibility loci and their role in survival. PMID: 22125638 |
Ref: Multiple factors influencing the release of hTERT mRNA from pancreatic cancer cell lines in in vitro culture. PMID: 21080909 Ref: Inhibition of cell proliferation and induction of apoptosis by oleanane triterpenoid (CDDO-Me) in pancreatic cancer cells is associated with the suppression of hTERT gene expression and its telomerase activity. PMID: 22609405 Ref: Regulation of tight junctions in human normal pancreatic duct epithelial cells and cancer cells. PMID: 22671593 Ref: Amadori-glycated phosphatidylethanolamine up-regulates telomerase activity in PANC-1 human pancreatic carcinoma cells. PMID: 22750441 Ref: Genetic markers of malignant transformation in intraductal papillary mucinous neoplasm of the pancreas: a meta-analysis. PMID: 22750975 Ref: hTERT-siRNA could potentiate the cytotoxic effect of gemcitabine to pancreatic cancer cells Bxpc-3. PMID: 22757972 Ref: Targeting claudin-4 in human pancreatic cancer. PMID: 22800288 Ref: TERT-CLPTM1L polymorphism rs401681 contributes to cancers risk: evidence from a meta-analysis based on 29 publications. PMID: 23226346 |
Ref: A novel EPAC-specific inhibitor suppresses pancreatic cancer cell migration and invasion. PMID: 23066090 Ref: A small-molecule induces apoptosis and suppresses metastasis in pancreatic cancer cells. PMID: 23313624 Ref: Inhibition of telomerase activity by oleanane triterpenoid CDDO-Me in pancreatic cancer cells is ROS-dependent. PMID: 23486104 Ref: GSK-3alpha promotes oncogenic KRAS function in pancreatic cancer via TAK1-TAB stabilization and regulation of noncanonical NF-kappaB. PMID: 23547054 Ref: Anti-pancreatic cancer deliverables from sea: first-hand evidence on the efficacy, molecular targets and mode of action for multifarious polyphenols from five different brown-algae. PMID: 23613993 Ref: Cellular and organismal toxicity of the anti-cancer small molecule, tolfenamic acid: a pre-clinical evaluation. PMID: 24030139 |
Ref: Association between CLPTM1L-TERT rs401681 polymorphism and pancreatic cancer risk among Chinese Han population. PMID: 24577890 Ref: P53, hTERT, WT-1, and VEGFR2 are the most suitable targets for cancer vaccine therapy in HLA-A24 positive pancreatic adenocarcinoma. PMID: 24633336 Ref: Variants associated with susceptibility to pancreatic cancer and melanoma do not reciprocally affect risk. PMID: 24642353 Ref: CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells. PMID: 24648346 Ref: Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. PMID: 25086665 Ref: Induction of Apoptosis in Pancreatic Cancer Cells by CDDO-Me Involves Repression of Telomerase through Epigenetic Pathways. PMID: 25152840 Ref: Elevation of MMP-9 and IDO induced by pancreatic cancer cells mediates natural killer cell dysfunction. PMID: 25274283 |
Ref: Leiomyosarcoma with alternative lengthening of telomeres is associated with aggressive histologic features, loss of ATRX expression, and poor clinical outcome. PMID: 25229770 Ref: Association between CLPTM1L-TERT rs401681 polymorphism and risk of pancreatic cancer: a meta-analysis. PMID: 25284078 Ref: Pharmacological inhibition and genetic knockdown of exchange protein directly activated by cAMP 1 reduce pancreatic cancer metastasis in vivo. PMID: 25385424 Ref: Design, synthesis, and biological evaluation of sulfonyl acrylonitriles as novel inhibitors of cancer metastasis and spread. PMID: 25581261 Ref: A Combinatory Strategy for Detection of Live CTCs Using Microfiltration and a New Telomerase-Selective Adenovirus. PMID: 25589497 Ref: Down regulation of miR-202 modulates Mxd1 and Sin3A repressor complexes to induce apoptosis of pancreatic cancer cells. PMID: 25611699 Ref: Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation. PMID: 25843513 Ref: TERT gene harbors multiple variants associated with pancreatic cancer susceptibility. PMID: 25940397 Ref: Association between the TERT Genetic Polymorphism rs2853676 and Cancer Risk: Meta-Analysis of 76,108 Cases and 134,215 Controls. PMID: 26042809 Ref: Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer. PMID: 26098869 Ref: PCDH10 Interacts With hTERT and Negatively Regulates Telomerase Activity. PMID: 26683936 Ref: [Determination of CEA, EGFR and hTERT expression in peritoneal lavage in patients with pancreatic adenocarcinoma using RT - PCR method]. PMID: 26766154 |
Ref: Melanoma genetics. PMID: 26337759 Ref: Pancreatic Tumor Progression Associated With CD133 Overexpression: Involvement of Increased TERT Expression and Epidermal Growth Factor Receptor-Dependent Akt Activation. PMID: 26646272 Ref: Enhancing the efficiency of bortezomib conjugated to pegylated gold nanoparticles: an in vitro study on human pancreatic cancer cells and adenocarcinoma human lung alveolar basal epithelial cells. PMID: 27087021 Ref: Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21. PMID: 27579533 |
Ref: Leucocyte telomere length, genetic variants at the TERT gene region and risk of pancreatic cancer. PMID: 27797938 Ref: Structural diversity of anti-pancreatic cancer capsimycins identified in mangrove-derived Streptomyces xiamenensis 318 and post-modification via a novel cytochrome P450 monooxygenase. PMID: 28098172 Ref: Familial melanoma and multiple primary melanoma. PMID: 28121081 Ref: Swollen Micelles for the Preparation of Gated, Squeezable, pH-Responsive Drug Carriers. PMID: 28374987 Ref: The TERT hypermethylated oncologic region predicts recurrence and survival in pancreatic cancer. PMID: 29019414 |
Ref: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). PMID: 29786110 Ref: A Scalable Method for Squalenoylation and Assembly of Multifunctional (64)Cu-Labeled Squalenoylated Gemcitabine Nanoparticles. PMID: 30324084 Ref: Genetic determinants of telomere length and risk of pancreatic cancer: a PANDoRA study. PMID: 30325019 Ref: Selective Photokilling of Human Pancreatic Cancer Cells Using Cetuximab-Targeted Mesoporous Silica Nanoparticles for Delivery of Zinc Phthalocyanine. PMID: 30355983 |