Primary Site >> Biliary tract Cancer
Gene >> TCFL5
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Ref: Adenosine triphosphate activates ion permeabilities in biliary epithelial cells. PMID: 8020667 Ref: Effect of ursodeoxycholic acid on intracellular pH in a bile duct epithelium-like cell line. PMID: 8276351 |
Ref: Molecular chemotherapy combined with radiation therapy enhances killing of cholangiocarcinoma cells in vitro and in vivo. PMID: 9331094 |
Ref: Killing effects of 5-fluorouracil on human biliary tract cancer cell lines. PMID: 9917499 Ref: Tumor-host interactions in the gallbladder suppress distal angiogenesis and tumor growth: involvement of transforming growth factor beta1. PMID: 10502827 Ref: The lipid products of phosphoinositide 3-kinase contribute to regulation of cholangiocyte ATP and chloride transport. PMID: 10521494 |
Ref: Enhanced radiation killing by 5-fluorouracil of biliary tract cancer cell lines. PMID: 10762635 Ref: Disrupted transforming growth factor-beta signaling and deregulated growth in human biliary tract cancer cells. PMID: 10842191 Ref: Fractionated radiation therapy in combination with adenoviral delivery of the cytosine deaminase gene and 5-fluorocytosine enhances cytotoxic and antitumor effects in human colorectal and cholangiocarcinoma models. PMID: 10871750 |
Ref: Interleukin-5 inhibition of biliary cell chloride currents and bile flow. PMID: 11254501 |
Ref: Stimulation of alpha2-adrenergic receptor inhibits cholangiocarcinoma growth through modulation of Raf-1 and B-Raf activities. PMID: 12029618 Ref: Tamoxifen (TMX)/Fas induced growth inhibition of human cholangiocarcinoma (HCC) by gamma interferon (IFN-gamma). PMID: 12035045 Ref: Inhibitory effect of epigallocatechin-3-gallate on growth and invasion in human biliary tract carcinoma cells. PMID: 12053219 Ref: H+-peptide cotransport in the human bile duct epithelium cell line SK-ChA-1. PMID: 12065310 |
Ref: Delta-aminolevulinic acid transport in cancer cells of the human extrahepatic biliary duct. PMID: 12649372 Ref: Inhibition of cholangiocarcinoma growth by tannic acid. PMID: 12717390 Ref: Celecoxib inhibits proliferation and induces apoptosis via prostaglandin E2 pathway in human cholangiocarcinoma cell lines. PMID: 12800245 |
Ref: The tumor-selective viral protein apoptin effectively kills human biliary tract cancer cells. PMID: 14647920 Ref: Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways. PMID: 14701718 Ref: Guanylin regulates chloride secretion in the human gallbladder via the bile fluid. PMID: 14988827 Ref: Influence of the site of human gallbladder xenograft (Mz-ChA-1) on angiogenesis at the distant site. PMID: 15010876 |
Ref: Portal fibroblasts regulate the proliferation of bile duct epithelia via expression of NTPDase2. PMID: 15799977 Ref: gamma-Aminobutyric acid inhibits cholangiocarcinoma growth by cyclic AMP-dependent regulation of the protein kinase A/extracellular signal-regulated kinase 1/2 pathway. PMID: 16357152 |
Ref: Treatment of cholangiocarcinoma with oncolytic herpes simplex virus combined with external beam radiation therapy. PMID: 16138120 Ref: Interleukin-6 decreases senescence and increases telomerase activity in malignant human cholangiocytes. PMID: 16336976 Ref: Expression of c-kit receptor in human cholangiocarcinoma and in vivo treatment with imatinib mesilate in chimeric mice. PMID: 16570351 Ref: Estrogens and insulin-like growth factor 1 modulate neoplastic cell growth in human cholangiocarcinoma. PMID: 16936263 |
Ref: Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing. PMID: 17241887 Ref: Proteasome inhibition-induces endoplasmic reticulum dysfunction and cell death of human cholangiocarcinoma cells. PMID: 17352013 Ref: Establishment of a novel orthotopic xenograft model of human gallbladder carcinoma. PMID: 17406986 Ref: Restoration of RUNX3 enhances transforming growth factor-beta-dependent p21 expression in a biliary tract cancer cell line. PMID: 17470130 |
Ref: Expression of the multidrug resistance proteins MRP2 and MRP3 in human cholangiocellular carcinomas. PMID: 18226047 Ref: Effect of histone deacetylase inhibitor on proliferation of biliary tract cancer cell lines. PMID: 18442209 Ref: beta-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes. PMID: 18772362 |
Ref: Endothelin inhibits cholangiocarcinoma growth by a decrease in the vascular endothelial growth factor expression. PMID: 19291182 Ref: Caffeic acid phenethyl ester decreases cholangiocarcinoma growth by inhibition of NF-kappaB and induction of apoptosis. PMID: 19358267 Ref: H3 histamine receptor-mediated activation of protein kinase Calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo. PMID: 19825989 Ref: Interaction among Rb/p16, Rb/E2F1 and HDAC1 proteins in gallbladder carcinoma. PMID: 20037816 |
Ref: Secretin inhibits cholangiocarcinoma growth via dysregulation of the cAMP-dependent signaling mechanisms of secretin receptor. PMID: 19904746 Ref: Arsenic trioxide inhibits cholangiocarcinoma cell growth and induces apoptosis. PMID: 20012722 Ref: Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling. PMID: 20347808 Ref: Mesothelin as a potential therapeutic target in human cholangiocarcinoma. PMID: 20922056 |
Ref: Loss of RUNX3 expression by histone deacetylation is associated with biliary tract carcinogenesis. PMID: 21205092 Ref: Simvastatin stimulates apoptosis in cholangiocarcinoma by inhibition of Rac1 activity. PMID: 21334995 Ref: Apoptosis of human cholangiocarcinoma cell lines induced by beta-escin through mitochondrial caspase-dependent pathway. PMID: 21394804 Ref: Melatonin exerts by an autocrine loop antiproliferative effects in cholangiocarcinoma: its synthesis is reduced favoring cholangiocarcinoma growth. PMID: 21778461 Ref: Myofibroblast-derived PDGF-BB promotes Hedgehog survival signaling in cholangiocarcinoma cells. PMID: 22038837 |
Ref: Inhibition of histidine decarboxylase ablates the autocrine tumorigenic effects of histamine in human cholangiocarcinoma. PMID: 21873469 |
Ref: Characterization of the erythropoietin/erythropoietin receptor axis in a rat model of liver damage and cholangiocarcinoma development. PMID: 23052842 Ref: Polo-like kinase 2 is a mediator of hedgehog survival signaling in cholangiocarcinoma. PMID: 23703673 Ref: Simvastatin enhances the chemotherapeutic efficacy of S-1 against bile duct cancer: E2F-1/TS downregulation might be the mechanism. PMID: 23941814 |
Ref: Non-canonical Hedgehog signaling contributes to chemotaxis in cholangiocarcinoma. PMID: 24239776 Ref: Mycoepoxydiene induces apoptosis and inhibits TPA-induced invasion in human cholangiocarcinoma cells via blocking NF-kappaB pathway. PMID: 24486723 Ref: Overexpression of membrane metalloendopeptidase inhibits substance P stimulation of cholangiocarcinoma growth. PMID: 24603459 Ref: XIAP antagonist embelin inhibited proliferation of cholangiocarcinoma cells. PMID: 24603802 Ref: Cordycepin down-regulates multiple drug resistant (MDR)/HIF-1alpha through regulating AMPK/mTORC1 signaling in GBC-SD gallbladder cancer cells. PMID: 25046749 |
Ref: Ursodeoxycholyl lysophosphatidylethanolamide inhibits cholestasis- and hypoxia-induced apoptosis by upregulating antiapoptosis proteins. PMID: 25125499 Ref: beta-escin reverses multidrug resistance through inhibition of the GSK3beta/beta-catenin pathway in cholangiocarcinoma. PMID: 25632187 Ref: Novel therapeutic strategy targeting the Hedgehog signalling and mTOR pathways in biliary tract cancer. PMID: 25742482 |
Ref: Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy. PMID: 26657503 Ref: miR-34a-dependent overexpression of Per1 decreases cholangiocarcinoma growth. PMID: 26923637 |
Ref: AICAR activates ER stress-dependent apoptosis in gallbladder cancer cells. PMID: 27847321 Ref: miR-24 Inhibition Increases Menin Expression and Decreases Cholangiocarcinoma Proliferation. PMID: 28087162 Ref: In vitro detection of cholangiocarcinoma cells using a fluorescent protein-expressing oncolytic herpes virus. PMID: 28409558 Ref: A rare variation of celiac trunk and hepatic artery complicating pancreaticoduodenectomy: A case report and literature review. PMID: 29310402 |
Ref: Blocking H1/H2 histamine receptors inhibits damage/fibrosis in Mdr2(-/-) mice and human cholangiocarcinoma tumorigenesis. PMID: 29601088 Ref: Transglutaminase 2 Mediates the Cytotoxicity of Resveratrol in a Human Cholangiocarcinoma and Gallbladder Cancer Cell Lines. PMID: 29757003 |