Primary Site >> Stomach Cancer

Gene >> TCF4

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Ref: Somatic frameshift alterations in mononucleotide repeat-containing genes in different tumor types from an HNPCC family with germline MSH2 mutation.
PMID: 10918391
Ref: Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis.
PMID: 12481159
Ref: Nuclear translocations of beta-catenin and TCF4 in gastric cancers correlate with lymph node metastasis but probably not with CD44 expression.
PMID: 16311123
Ref: Gastric cancer with high-level microsatellite instability: target gene mutations, clinicopathologic features, and long-term survival.
PMID: 18440592
Ref: CpG methylation in exon 1 of transcription factor 4 increases with age in normal gastric mucosa and is associated with gene silencing in intestinal-type gastric cancers.
PMID: 18635522
Ref: RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis.
PMID: 18772112
Ref: CpG methylation of transcription factor 4 in gastric carcinoma.
PMID: 20585880
Ref: Diverse mechanisms of Wnt activation and effects of pathway inhibition on proliferation of human gastric carcinoma cells.
PMID: 21042278
Ref: H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model.
PMID: 23471915
Ref: EphA2 promotes epithelial-mesenchymal transition through the Wnt/beta-catenin pathway in gastric cancer cells.
PMID: 23752181
Ref: Context-dependent activation of Wnt signaling by tumor suppressor RUNX3 in gastric cancer cells.
PMID: 24447505
Ref: Expression of the E-cadherin/beta-catenin/tcf-4 pathway in gastric diseases with relation to Helicobacter pylori infection: clinical and pathological implications.
PMID: 24528029
Ref: Differential regulation analysis reveals dysfunctional regulatory mechanism involving transcription factors and microRNAs in gastric carcinogenesis.
PMID: 28545608
Ref: The Wnt/beta-catenin and PI3K/Akt signaling pathways promote EMT in gastric cancer by epigenetic regulation via H3 lysine 27 acetylation.
PMID: 28671020
Ref: TCF4/beta-catenin complex is directly upstream of FGF21 in mouse stomach cancer cells.
PMID: 29434695
Ref: SMYD3 controls a Wnt-responsive epigenetic switch for ASCL2 activation and cancer stem cell maintenance.
PMID: 29746925
Ref: Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer.
PMID: 29765046
Ref: MiR-361-5p inhibits the mobility of gastric cancer cells through suppressing epithelial-mesenchymal transition via the Wnt/beta-catenin pathway.
PMID: 29960070
Ref: Antitumor evaluation of novel phenothiazine derivatives that inhibit migration and tubulin polymerization against gastric cancer MGC-803 cells.
PMID: 30345465
Ref: Loss of endogenous RNF43 function enhances proliferation and tumour growth of intestinal and gastric cells.
PMID: 30380024