Primary Site >> Colorectal Cancer

Gene >> TCF12

  • 2011
  • 2012
  • 2013
  • 2018
Ref: Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis.
PMID: 21999571
Ref: TCF12 protein functions as transcriptional repressor of E-cadherin, and its overexpression is correlated with metastasis of colorectal cancer.
PMID: 22130667
Ref: Secreted heat shock protein 90alpha (HSP90alpha) induces nuclear factor-kappaB-mediated TCF12 protein expression to down-regulate E-cadherin and to enhance colorectal cancer cell migration and invasion.
PMID: 23386606
Ref: Osteopontin-integrin engagement induces HIF-1alpha-TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer.
PMID: 29435158