Primary Site >> Liver Cancer
Gene >> TBX3
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Ref: Tbx3 is a downstream target of the Wnt/beta-catenin pathway and a critical mediator of beta-catenin survival functions in liver cancer. PMID: 17283120 |
Ref: The ulnar-mammary syndrome gene, Tbx3, is a direct target of the retinoic acid signaling pathway, which regulates its expression during mouse limb development. PMID: 22535523 Ref: Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib. PMID: 22811581 |
Ref: Apicidin-resistant HA22T hepatocellular carcinoma cells strongly activated the Wnt/beta-catenin signaling pathway and MMP-2 expression via the IGF-IR/PI3K/Akt signaling pathway enhancing cell metastatic effect. PMID: 24317053 Ref: WNT signaling pathway gene polymorphisms and risk of hepatic fibrosis and inflammation in HCV-infected patients. PMID: 24386373 |
Ref: [Inhibitory effect of Biejiajian pills on HepG2 cell xenograft growth and expression of beta-catenin and Tbx3 in nude mice]. PMID: 26922018 |
Ref: DNA Methylation Changes in Tbx3 in a Mouse Model Exposed to Polybrominated Diphenyl Ethers. PMID: 28466692 |
Ref: T-box transcription factor Tbx3 contributes to human hepatocellular carcinoma cell migration and invasion by repressing E-cadherin expression. PMID: 29295731 Ref: Novel HDAC5-interacting motifs of Tbx3 are essential for the suppression of E-cadherin expression and for the promotion of metastasis in hepatocellular carcinoma. PMID: 30151243 Ref: High Frequency of beta-Catenin Mutations in Mouse Hepatocellular Carcinomas Induced by a Nongenotoxic Constitutive Androstane Receptor Agonist. PMID: 30201494 Ref: Necroptosis microenvironment directs lineage commitment in liver cancer. PMID: 30209397 Ref: The special stemness functions of Tbx3 in stem cells and cancer development. PMID: 30268432 |