Primary Site >> Colorectal Cancer
Gene >> TAP2
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Ref: Loss of major histocompatibility complex-encoded transporter associated with antigen presentation (TAP) in colorectal cancer. PMID: 8080034 |
Ref: Total loss of MHC class I in colorectal tumors can be explained by two molecular pathways: beta2-microglobulin inactivation in MSI-positive tumors and LMP7/TAP2 downregulation in MSI-negative tumors. PMID: 12694570 |
Ref: Immunoselective pressure and human leukocyte antigen class I antigen machinery defects in microsatellite unstable colorectal cancers. PMID: 16024646 |
Ref: Correlation between expression of major histocompatibility complex class I and that of antigen presenting machineries in carcinoma cell lines of the pancreas, biliary tract and colon. PMID: 16855371 |
Ref: MUTYH-associated polyposis carcinomas frequently lose HLA class I expression - a common event amongst DNA-repair-deficient colorectal cancers. PMID: 19462419 |
Ref: Down-regulation of the antigen processing machinery is linked to a loss of inflammatory response in colorectal cancer. PMID: 20869097 |
Ref: Methylation-specific ligation detection reaction (msLDR): a new approach for multiplex evaluation of methylation patterns. PMID: 21879293 Ref: The LMP7-K allele of the immunoproteasome exhibits reduced transcript stability and predicts high risk of colon cancer. PMID: 22037870 |
Ref: PSMB8 as a Candidate Marker of Responsiveness to Preoperative Radiation Therapy in Rectal Cancer Patients. PMID: 28721901 |