Primary Site >> Colorectal Cancer

Gene >> TAP1

  • 1994
  • 2000
  • 2003
  • 2004
  • 2005
  • 2006
  • 2009
  • 2010
  • 2011
  • 2014
  • 2015
Ref: Loss of major histocompatibility complex-encoded transporter associated with antigen presentation (TAP) in colorectal cancer.
PMID: 8080034
 Ref: Overexpression of Cdx1 and Cdx2 homeogenes enhances expression of the HLA-I in HT-29 cells.
PMID: 10964750
 Ref: Total loss of MHC class I in colorectal tumors can be explained by two molecular pathways: beta2-microglobulin inactivation in MSI-positive tumors and LMP7/TAP2 downregulation in MSI-negative tumors.
PMID: 12694570
 Ref: MHC class I antigen processing pathway defects, ras mutations and disease stage in colorectal carcinoma.
PMID: 14750179
 Ref: Immunoselective pressure and human leukocyte antigen class I antigen machinery defects in microsatellite unstable colorectal cancers.
PMID: 16024646
 Ref: Correlation between expression of major histocompatibility complex class I and that of antigen presenting machineries in carcinoma cell lines of the pancreas, biliary tract and colon.
PMID: 16855371
 Ref: MUTYH-associated polyposis carcinomas frequently lose HLA class I expression - a common event amongst DNA-repair-deficient colorectal cancers.
PMID: 19462419
 Ref: Down-regulation of the antigen processing machinery is linked to a loss of inflammatory response in colorectal cancer.
PMID: 20869097
 Ref: Chemotherapeutic agents in low noncytotoxic concentrations increase immunogenicity of human colon cancer cells.
PMID: 21290210
Ref: Methylation-specific ligation detection reaction (msLDR): a new approach for multiplex evaluation of methylation patterns.
PMID: 21879293
Ref: The LMP7-K allele of the immunoproteasome exhibits reduced transcript stability and predicts high risk of colon cancer.
PMID: 22037870
 Ref: The genotype of the transporter associated with antigen processing gene affects susceptibility to colorectal cancer in Japanese.
PMID: 24803408
 Ref: High ABCC2 and low ABCG2 gene expression are early events in the colorectal adenoma-carcinoma sequence.
PMID: 25793771